Conflicts of interest: None.
Tropical medicine rounds
Follicular cutaneous larva migrans: a report of three cases and review of the literature
Article first published online: 17 FEB 2013
© 2013 The International Society of Dermatology
International Journal of Dermatology
Volume 52, Issue 3, pages 327–330, March 2013
How to Cite
Veraldi, S., Persico, M. C., Francia, C., Nazzaro, G. and Gianotti, R. (2013), Follicular cutaneous larva migrans: a report of three cases and review of the literature. International Journal of Dermatology, 52: 327–330. doi: 10.1111/j.1365-4632.2012.05723.x
- Issue published online: 17 FEB 2013
- Article first published online: 17 FEB 2013
Hookworm-related cutaneous larva migrans (CLM) is characterized clinically by erythematous and slightly raised tracks, located especially on the feet. These tracks may be single or multiple, linear or serpiginous, more or less ramified and intertwined. The length is variable (up to many cm); the width ranges from 1 mm to 4 mm. Tracks are often accompanied by severe pruritus.
Three adult Caucasian patients recently returned from trips to Malaysia and Thailand, presented with follicular CLM. The disease was characterized clinically by follicular, erythematous, small papules that were sometimes topped with vesicles or pustules, located on the buttocks. Pruritus was severe.
Histopathological examinations revealed a perifollicular infiltrate predominantly consisting of lymphocytes and eosinophils. All patients were successfully treated with oral albendazole (400 mg/day for seven days). In the first patient, two courses were necessary.
Dermatologists should be aware of the existence of this rare and atypical, although emerging, clinical presentation of hookworm-related CLM.