The authors have no relevant conflicts of interest.
Molecularly targeted therapies for melanoma
Article first published online: 17 APR 2013
© 2013 The International Society of Dermatology
International Journal of Dermatology
Volume 52, Issue 5, pages 523–530, May 2013
How to Cite
Liu, L. S. and Colegio, O. R. (2013), Molecularly targeted therapies for melanoma. International Journal of Dermatology, 52: 523–530. doi: 10.1111/j.1365-4632.2012.05829.x
- Issue published online: 17 APR 2013
- Article first published online: 17 APR 2013
Systemic and topical targeted therapies are emerging as a rational approach to the management of skin cancers. In this article, we review the molecular pathways critical to the development of melanoma and the novel pharmacologic agents that have been rationally designed to target it. Included is a review of vemurafenib, imatinib, and ipilimumab for metastatic or unresectable melanoma.