Conflict of Interest: None
Pharmacology and Therapeutics
Ear, nose, and throat involvement in Egyptian patients with pemphigus vulgaris: a step towards a better management
Article first published online: 8 JUL 2013
© 2013 The International Society of Dermatology
International Journal of Dermatology
Volume 52, Issue 10, pages 1268–1273, October 2013
How to Cite
Fawzy, M. M., Hegazy, R. A. and Abdel Fattah, A. F. (2013), Ear, nose, and throat involvement in Egyptian patients with pemphigus vulgaris: a step towards a better management. International Journal of Dermatology, 52: 1268–1273. doi: 10.1111/j.1365-4632.2012.05846.x
- Issue published online: 23 SEP 2013
- Article first published online: 8 JUL 2013
The frequency of ear, nose, and throat (ENT) involvement in pemphigus vulgaris (PV) is not clear; thereby, the importance of setting routine ENT examination for patients with PV could not be deduced.
Determine the prevalence of ENT involvement in patients with PV in Egypt; to modify the routine protocol and achieve a step towards better management.
Patients and methods
Thirty-four patients with PV were included. Patients were asked about ENT symptomatology and evaluated for ENT manifestations.
Twenty-five patients complained from ENT symptoms (74%). The pharyngeal/laryngeal-related symptoms were the most common. Eighty-two percent of patients had positive endoscopic findings. The most common were pharyngeal/laryngeal (76.5%). In total, the positive endoscopic findings superseded the positive symptomatic findings. More severe involvement was documented in non-smoking patients (P < 0.05).
Full ENT examination as a routine for all patients with PV could be of great value, as it would lead to more accurate diagnosis, therefore improved management.