Ear, nose, and throat involvement in Egyptian patients with pemphigus vulgaris: a step towards a better management


  • Conflict of Interest: None


Dr. Marwa Mohamed Fawzy

Departments of Dermatology

Faculty of Medicine

Cairo University

511a1 Ahram Street

Giza, Egypt

E-mail: marwamohamedfawzi@hotmail.com



The frequency of ear, nose, and throat (ENT) involvement in pemphigus vulgaris (PV) is not clear; thereby, the importance of setting routine ENT examination for patients with PV could not be deduced.


Determine the prevalence of ENT involvement in patients with PV in Egypt; to modify the routine protocol and achieve a step towards better management.

Patients and methods

Thirty-four patients with PV were included. Patients were asked about ENT symptomatology and evaluated for ENT manifestations.


Twenty-five patients complained from ENT symptoms (74%). The pharyngeal/laryngeal-related symptoms were the most common. Eighty-two percent of patients had positive endoscopic findings. The most common were pharyngeal/laryngeal (76.5%). In total, the positive endoscopic findings superseded the positive symptomatic findings. More severe involvement was documented in non-smoking patients (< 0.05).


Full ENT examination as a routine for all patients with PV could be of great value, as it would lead to more accurate diagnosis, therefore improved management.