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Ear, nose, and throat involvement in Egyptian patients with pemphigus vulgaris: a step towards a better management


  • Conflict of Interest: None


Dr. Marwa Mohamed Fawzy

Departments of Dermatology

Faculty of Medicine

Cairo University

511a1 Ahram Street

Giza, Egypt




The frequency of ear, nose, and throat (ENT) involvement in pemphigus vulgaris (PV) is not clear; thereby, the importance of setting routine ENT examination for patients with PV could not be deduced.


Determine the prevalence of ENT involvement in patients with PV in Egypt; to modify the routine protocol and achieve a step towards better management.

Patients and methods

Thirty-four patients with PV were included. Patients were asked about ENT symptomatology and evaluated for ENT manifestations.


Twenty-five patients complained from ENT symptoms (74%). The pharyngeal/laryngeal-related symptoms were the most common. Eighty-two percent of patients had positive endoscopic findings. The most common were pharyngeal/laryngeal (76.5%). In total, the positive endoscopic findings superseded the positive symptomatic findings. More severe involvement was documented in non-smoking patients (< 0.05).


Full ENT examination as a routine for all patients with PV could be of great value, as it would lead to more accurate diagnosis, therefore improved management.