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Monoamine oxidase A variants are associated with heavy betel quid use

  1. Ping-Ho Chen1,2,
  2. Hung-Pin Tu3,4,
  3. Shu-Jung Wang2,
  4. Albert Min-Shan Ko2,
  5. Chi-Pin Lee4,
  6. Tai-An Chiang9,
  7. Yi-Shan Tsai2,
  8. Chien-Hung Lee2,5,
  9. Tien-Yu Shieh7,8,
  10. Chih-Hung Ko5,
  11. Shang-Lun Chiang2,
  12. Ying-Chin Ko2,3,*

Article first published online: 26 APR 2011

DOI: 10.1111/j.1369-1600.2011.00331.x

Issue

Addiction Biology

Addiction Biology

Volume 17, Issue 4, pages 786–797, July 2012

Additional Information

How to Cite

Chen, P.-H., Tu, H.-P., Wang, S.-J., Ko, A. M.-S., Lee, C.-P., Chiang, T.-A., Tsai, Y.-S., Lee, C.-H., Shieh, T.-Y., Ko, C.-H., Chiang, S.-L. and Ko, Y.-C. (2012), Monoamine oxidase A variants are associated with heavy betel quid use. Addiction Biology, 17: 786–797. doi: 10.1111/j.1369-1600.2011.00331.x

Author Information

  1. 1

    School of Dentistry, College of Dental Medicine

  2. 2

    Center of Excellence for Environmental Medicine

  3. 3

    Department of Public Health and Environmental Medicine, Faculty of Medicine, College of Medicine

  4. 4

    Graduate Institute of Medicine, College of Medicine

  5. 5

    Department of Public Health

  6. 7

    Graduate Institute of Dental Sciences, College of Dental Medicine

  7. 8

    Department of Psychiatry, Faculty of Medicine, College of Medicine

  8. 9

    Kaohsiung Medical University, Taiwan and The Department of Medical Laboratory Science and Biotechnology, College of Medicine and Life Science, Chung-Hwa University of Medical Technology, Taiwan

*Ying-Chin Ko, Department of Public Health, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, no. 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan. E-mail: ycko@kmu.edu.tw

Publication History

  1. Issue published online: 2 JUL 2012
  2. Article first published online: 26 APR 2011

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Figure S1 Cytotoxicity effects of areca nut extract (ANE) and arecoline (ARE) to cell morphology.

Table S1MAO-A gene variants and substance (betel quid, cigarette, and alcohol) use behaviours.

Table S2 Joint effects and adjusted population attributable risk percent (aPAR%) of high-exposure BQ and non-BQ chewers associated with MAO-A allele variants, stratified by drinking alcohol status.

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ADB_331_sm_FigS1.doc639KSupporting info item
ADB_331_sm_TableS1-2.doc89KSupporting info item

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