Stress history increases alcohol intake in relapse: relation to phosphodiesterase 10A
Article first published online: 28 JUN 2012
© 2012 The Authors. Addiction Biology © 2012 Society for the Study of Addiction
Volume 17, Issue 5, pages 920–933, September 2012
How to Cite
Logrip, M. L. and Zorrilla, E. P. (2012), Stress history increases alcohol intake in relapse: relation to phosphodiesterase 10A. Addiction Biology, 17: 920–933. doi: 10.1111/j.1369-1600.2012.00460.x
- Issue published online: 14 SEP 2012
- Article first published online: 28 JUN 2012
Figure S1 Lack of modulation of nucleus accumbens (NAc) Pde10a by stress history or baseline drinking level. At the conclusion of relapse-like alcohol self-administration, no differences were observed in NAc Pde10a expression based on stress history (a) or baseline drinking level (b). Additionally, subdivision of rats according to baseline drinking level yielded no differences according to stress history in low (c) or high (d) drinkers. Data are expressed as LSMeans ± SE for Pde10a, controlled for Cyp covariate effects following z-score transformation of gene expression data. n = 23–24 (a–b) or 10–13 (c–d) per group.
Appendix S1 Supplemental Methods.
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