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Keywords:

  • aspirin intolerance;
  • aspiryl antibodies;
  • bronchospasm;
  • chronic urticaria;
  • normal adult population;
  • normal pediatric population

The frequency of aspirin intolerance by history in 2,592 normal individuals was 0.3%. Although the frequency of aspirin intolerance was similar in adults and children, the bronchospastic type predominated in adults, and only the urticarial regardless of etiology, was significantly greater in adults than in children. The frequency of recurrent urticaria, regardless of etiology, was significantly greater in adults than in children (3.8% vs. 0.3, P<0.001). In adults the frequency of aspirin intolerance was over 20 times greater in individuals with recurrent urticaria than in normal individuals (6.5% vs. 0.3%, P<0.001).