Antigens Common to Scabies and House Dust Mites

Authors

  • Edvard S. Falk,

    Corresponding author
    1. Dept. of Dermatology and Dept. of Pediatrics, University of Tromsø, Tromsø, and Nyco & Co. A/S, Oslo, Norway
      Edvard S. Falk, Dept. of Dermatology, University of Tromsø, Tromsø, Norway
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  • Siri Dale,

    1. Dept. of Dermatology and Dept. of Pediatrics, University of Tromsø, Tromsø, and Nyco & Co. A/S, Oslo, Norway
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  • Roald Bolle,

    1. Dept. of Dermatology and Dept. of Pediatrics, University of Tromsø, Tromsø, and Nyco & Co. A/S, Oslo, Norway
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  • Bjørn Haneberg

    1. Dept. of Dermatology and Dept. of Pediatrics, University of Tromsø, Tromsø, and Nyco & Co. A/S, Oslo, Norway
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Edvard S. Falk, Dept. of Dermatology, University of Tromsø, Tromsø, Norway

Abstract

Twenty-five antigens were demonstrated in a crude Dermatophagoides farinae (DF) extract by means of crossed immunoelectrophoresis (CIE), using a rabbit anti-DF serum. With the same antiserum, four antigens were demonstrated in a scabies mite preparation, indicating an immunological relationship between these scabies antigens and some of the DF antigens. In tandem CIE experiments the DF antigens were found to be partly identical to three of the scabies antigens. No IgE activity against any of these scabies antigens was evident in pooled sera from patients with house dust mite allergy by crossed radioimmunoelectrophoresis. However, one such patient had IgE antibodies to a DF antigen and a partial identical scabies antigen.

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