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References

  • 1
    Chai H, Farr RS, Froehlich LA et al. Standardization of bronchial inhalation challenge procedures. J Allergy Clin Immunol 1975;50:323.
  • 2
    Aas K. The bronchial provocation test. Springfield, IL Charles C. Thomas, 1975.
  • 3
    Spector SL. Provocative challenge procedures. Vol. 1. Boca Raton, FL: CRC Press, 1983.
  • 4
    Davies RJ, Morgan DJR, Osman J et al. Bronchial provocation tests. In: KerrJW, GoudertonMA, ed. Proc XI Int Cong Allergol Clin Immunol, London 17–22 Oct. 1982; London: Macmillan Press, 1983:213.
  • 5
    Spector SL. Physiologic changes that occur in response to allergen induced challenge. Clin Rev Allergy 1985;3:463.
  • 6
    Debelic M, Radelovíc P Tests de provocation bronchiques aux allergènes dans le diagnostic de l'asthma bronchique. Série sur 1′Asthma 11. Basle: Sandoz, 1986.
  • 7
    Debelic M. Bronchial provocation tests with allergens in clinical practice. In: MemoG, NormanP, MaroneG, ed. Respiratory allergy. Clinical immunology, Vol. 2. Toronto: B.C. Decker, 1990:233.
  • 8
    Pauli G. Les tests de provocation bronchique specifiques. Prax-Klin Pneumol 1988;42:278.
  • 9
    Mausmann HC. Allergy tests in clinical diagnosis. In: BiermanCW, PearlmanDS, ed. Allergic diseases of infancy, childhood and adolescence. Philadelphia: W.B. Sanders Co., 1980:289.
  • 10
    Michel FB, Godard P, Bousquet J et al. Evaluation of allergenic challenge in diagnosis of allergic asthma and antiasthma drugs research. J Aerosol Med 1991;4 (suppl 1):61.
  • 11
    Spector SL, Fazz RS. Bronchial inhalation procedures in asthmatics. Med Clin North Am 1974;58:71.
  • 12
    Mosbech H et al. House dust mite asthma. Correlation between allergen sensitivity in various organs. Allergy 1987;42:456.
  • 13
    Huggins KG, Brostoff J. Local production of specific IgE antibodies in allergic rhinitis with negative skin tests. Lancet 1975;ii:148.
  • 14
    Malling HJ, Weeke B. Position paper: immunotherapy. Allergy 1993;14(suppl 48):9.
  • 15
    Rosenthal RR. Inhalation challenge. In: MelilloG, NormanPS, MaroneG, ed. Respiratory allergy. Toronto: B.C. Decker, 1990:1930.
  • 16
    Pelikan Z, Pelikan M. Early and late asthmatic response to allergen challenge and their pharmacological modulation. Ann Allergy 1985;55:318 (Abstr 372).
  • 17
    Melillo G, Cocco G. Bronchial challenge in pollen asthma. In: FalagianiP, ed. Pollinosis, Boca Raton, FL: CRC Press, 1990:153.
  • 18
    Liejens HJT, Degenhart HS, Ruatgeep HE et al. Study on the significance of bronchial hyperreactivity in the bronchus obstruction after inhalation of cat induced dander allergen. J Allergy Clin Immunol 1979;54:507.
  • 19
    Schultze-Werninghouse G, Levy J, Bergman EM et al. Clinical significance of airborne Alternaria spores: tenuis sysonal symptoms, positive skin and bronchial challenge tests with Ahernaria in subjects asthma and rhinitis. Experientia 1987:suppl 51:153.
  • 20
    Pelikan Z, Pelikan-Filipek M. Isolated and dual type of late asthmatic response, the clinical feature and pharmacological control. J Allergy Clin Immunol 1989;83:210 (Abstr 153).
  • 21
    Lopez M, Voigtlander JR, Lehr SB, Salvaggio JE. Broncho-provocation studies in basic studies in Basidio spore-sensitive subjects with asthma. J Allergy Clin Immunol 1989;84:242.
  • 22
    Daza JC, Aviles C, Arenas AS. Development of a protocol for application of the Alternaria specific bronchial provocation test to children (Abst.). Schweiz Med Wochenschr 1991:Suppl 40/II, 69.
  • 23
    Novembre E, Marano E, Bernardini R et al. The hazard of persistent reactions after bronchial provocation tests with Alternaria in children (Abst.). Schweiz Med Wochenschr 1991:Suppl. 40/II, 69.
  • 24
    Ingram CG, Jeffrey IG, Symingston IS et al. Bronchial provocation studies in farmers allergic to storage mites. Lancet 1979;ii:1330.
  • 25
    Van Hage, Austen M, Ihre E et al. Bronchial provocation studies in farmers with positive RAST to the storage with Lepidogly.
  • 26
    Pola J, Valdiviero R, Zapata C et al. Specific bronchial challenge in cockroach asthma. Allergol Immunopathol 1988;16:171.
  • 27
    Kong BL, Johnson J, Morgan C et al. The role of immunotherapy in cockroach asthma. J Asthma 1988;25:218.
  • 28
    Bruce CA, Rosenthal RR, Lichtenstein LM, Norman PS. Quantitative inhalation bronchial challenge in ragweed hay fever patients: a comparison with ragweed allergic asthmatics. J Allergy Clin Immunol 1975;56:331.
  • 29
    Permut S, Rosenthal RR, Norman PS, Menkes HA. Bronchial challenge in ragweed sensitive patients. In: LichtenstienLM, AustenKF, ed. Asthma, physiology, immunopharmacology and treatment. New York Academic Press, 1977.
  • 30
    Aas K. Discussion. In: LichtensteinLM, AustenKF, ed. Asthma, physiology, immunopharmacology and treatment. New York: Academic Press, 1977:277.
  • 31
    Melillo G. Allergen inhalation challenge with a micronized freeze-dried extract administered by a powder inhaler. In: MelilloG, NormanPS, MaroneG, ed. Respiratory allergy. Clinical immunology. Vol. 2, Toronto: BC Decker, 1990:207.
  • 32
    Lowagen O, Lindholm NB. Standardized provocation tests. J Allergy 1980;35:349.
  • 33
    Fralund L, Madsen F, Svendsen UG et al. Reproducibility of standardized provocation tests. Allergy 1986;30:41.
  • 34
    Kopperschmitt HC, Bigot H, Pauli G. Allergen bronchial challenge tests. Variability and reproducibility of the early response. J Allergy Clin Immunol 1987;57:30.
  • 35
    Melillo G, Aas K, Cartier A et al. Guidelines for the standardization of bronchial provocation tests with allergens. Allergy 1991;46:321.
  • 36
    Dreborg S. Skin prick test. An update. G Ital Allergol Immunol Clin 1988;3:35.
  • 37
    Aas K. Adequate clinical trial of immunotherapy. Allergy 1982;37:1.
  • 38
    Warner JO, Price JF, Soothil IF et al. Controlled trial of hyposensitization to Dermatophaigodes pteronyssinus in children with asthma. Lancet 1978;29:12.
  • 39
    Norman PS. Challenge techniques in the evaluation of immunotherapy. In: ReedCE ed. Proc III Int Congr Allergy Clin Immunol. St. Louis: Mosby, 1985:319.
  • 40
    Swineford O et al. Tkeatment of pollen hay fever and asthma with aerosols of pollen extracts. J Allergy 1955;26:305.
  • 41
    McAllen MK. Bronchial sensitivity testing in asthma: an assessment of the effect of hyposensitization in house dust and pollen sensitivity asthmatics. Thorax 1961;10:16.
  • 42
    McAllen MK, Heag PS, Mcinoy P. Depot grass pollen injections in asthma. Effect of repeated treatment on clinical responses and measured bronchial sensitivity. Br Med J 1967;1:22.
  • 43
    Thlhida M et al. Effect of immunotherapy in chronic asthmatic children. J Allergy Clin Immunol 1973;5:1311.
  • 44
    Taylor WW et al. Immunotherapy in cat-induced asthma. Double blind trial with evaluation of bronchial responses to cat allergen and histamine. J Allergy Clin Immunol 1978;283.
  • 45
    Valvistar E et al. Immunotherapy in allergy to dog: a double blind clinical study. Ann Allergy 1984;53:85.
  • 46
    Ohman JL, Fiidlay SA, Leiterman KM. Immunotherapy in cat-induced asthma. Double blind trial with evaluation of in vivo and in vitro responses. J Allergy Clin Immunol 1984;74:230.
  • 47
    Wahn U, Schwater C, Lind P et al. Prospective study on immunologic changes induced by two different Dermataphagoides pteronyssinus extracts prepared from whole mite culture and mite bodies. J Allergy Clin Immunol 1988;82:360.
  • 48
    Aas K. Hyposensitization in house dust allergic asthma. A double blind controlled study with evaluation of the effect in bronchial sensitivity to house dust. Acta Paediatr Scand 1972;60:264.
  • 49
    Hongard L, Dahl R. A controlled dose-response study of immunotherapy with standardized, partially purified extract of house dust mite: clinical efficacy and side effects. J Allergy Clin Immunol 1993;91:709.
  • 50
    Melillo G. Local immunotherapy by inhalation of allergic asthma. Preliminary results of a multi-center study. In: MelilloG, CoccoG, CentanniG ed. Proc XIII Cong EAACI, Budapest, 1986. The use of allergen in powder form for provocation tests and for local immunotherapy in allergic asthma. Naples: Publ. Forum Editorial, 1986.
  • 51
    Warner JD, Price JF, Southill JF et al. Controlled trial of hyphosensitization to Dermatophagoides pteronyssinus in children with asthma. Lancet 1978;2:912.
  • 52
    Metzer WJ, Donald BA, Richardson HB. Modification of late responses during immunotherapy for Alternaria-induced asthma. (Abstr) J Allergy Clin Immunol 1983;71:119.
  • 53
    Gleich GI. The late phase of the immunoglobulin E-mediated reaction: a link between anaphylaxis and common allergic disease. J Allergy Clin Immunol 1982;70:160.
  • 54
    Kaliner M. Hypotheses on the contribution of late phase allergic response to the understanding and treatment of allergic disease. J Allergy Clin Immunol 1984;73:311.
  • 55
    Lichtenstein LM, Valentine MD, Norman PS. A reevalu-ation of immunotherapy for asthma. Allergy Rev Respir 1984;129:657.
  • 56
    Maestrelli P, Boschetto P. Inhibition of allergen induced late asthmatic reaction after local immunotherapy with inhaled extract of Dennatophagoides pteronyssinus. Proc XIII Cong EAACI, Budapest 1986. In: MelilloG, CoccoG, CentanniG. ed. The use of allergen in powder form for provocation tests and for local immunotherapy in allergic asthma. Naples: Forum Ed, 1986:100.
  • 57
    Van Bever HP, Stevens WJ. Suppression of late asthmatic reaction by hyposensitization in asthmatic children allergic to house dust mite. Clin Exp Allergy 1989;19:399.
  • 58
    Van Bever HP, Stevens WJ. Evolution of the late asthmatic reaction during immunotherapy and after stopping immunotherapy. J Allergy Clin Immunol 1990;141.
  • 59
    Shampain MP, Behrens RL, Larsen GL et al. An animal model of late pulmonary responses to Alternuria challenge. Am Rev Respir Dis 1982;126:493.
  • 60
    Behrnus L, Clark RAF, Marsh W et al. Modulation of late asthmatic response by antigen specific immunoglobulin in animal models. Am Rev Respir Dis 1984;130:1134.
  • 61
    Cairns H. Models for the development of antiasthmatic drugs. In: PepysJ, EdwardsMM eds The mast cell its role in health and disease. London: Pitman Publishers, 1979:172.
  • 62
    Lichtenstein LM, Margolis S. Histamine release in vitro: inhibition by catecholamine and methylxathines. Science 1968;902:161.
  • 63
    Ishizaka I, Ishizaka K, Orange RP, Austen KE Pharma-cologic inhibition of the antigen-induced release of hista-mines and slow-reacting substance of anaphylaxis (SRS-A) from monkey lung tissues mediated by human IgE. J Immunol 1971;106:1267.
  • 64
    Bonn HR, Lichtenstein LM, Melmon KL. Pharmacologic control of allergic histamine release in vitro: evidence for an inhibitory role of 3′, 5′ adenosine monophosphate in human leucocytes. J Immunol 1972;100:695.
  • 65
    Church MK, Hiroi J. Inhibition of IgE-dependent histamine release from human dispersed lung mast cells by antiallergic drugs and salbutamol. Br J Pharmacol 1987;90:421.
  • 66
    Kran J, Koëter GH, Van ver Mark TW et al. Change in bronchial hyperreactivity induced by 4 week treatment with anti-asthmatic drugs in allergic asthmatic patients: a comparison between budesonide and terbutaline. J Allergy Clin Immunol 1985;76:628.
  • 67
    Kerrebijn KF, Van Essen Zanduliet EEM, Nagens HJ. Effects of long-term treatment with inhaled corticosteroids and beta-agonists on the bronchial responsiveness in children with asthma. J Allergy Clin Immunol 1987;79:635.
  • 68
    Skidmore IE Beta-agonists as mast-cell stabilizers In: KayAB, ed. Asthma: clinical, pharmacology and therapeutic progress. London: Blackwell Scientific Publishers, 1980:171.
  • 69
    Fish JE, Newball HH, Lenfant C. In vivo immuno pharmacology of the lung. In: NewballHH, ed. Immunopharma-cology of the lung. New York: Marcel Dekker, 1983:273.
  • 70
    Hutchcroft B. Discussion. In: LichtensteinLM, AustenKF, ed. Asthma, Physiology, immunopharmacology and treatment. New York: Academic Press, 1977:14.
  • 71
    Bryant DH, Bums MW. Bronchial histamine reactivity: its relationship to the reactivity of the bronchi to allergens. Clin Allergy 1976;6:523.
  • 72
    Killian D, Cockcroft DW, Hargreave FE, Dolovich J. Factors in allergen-induced asthma: relevance of intensity of the airways allergic reaction and non specific bronchial reactivity. Clin Allergy 1976;6:219.
  • 73
    Cockcroft DW, Duffin RE, Frith GA et al. Determinants of allergen-induced asthma: dose of allergen, circulating IgE antibody concentration and bronchial responsiveness to inhaled histamine. Am Rev Respir Dis 1979;120:1053.
  • 74
    Melillo G, Cocco G, Schiano M, Balzano G. Relationship between atopy and non-specific bronchial hyperrespon-siveness in asthma. In: OlivieriD, BiancoS, ed. Airway obstruction and inflammation. Prog Respir Dis Basel: Karger, 1990:151.
  • 1
    Aas K, Backmann A, Belin L, Weeke B. Standardization of allergen extracts with appropriate methods. The combined use of skin prick testing and radioallergosorbent test. Allergy 1978;33:13037.
  • 2
    Belin L. Standardized extracts, trees. Clin Rev Allergy 1986;4:389404.
  • 3
    BernsteinIC. ed. Report of the American Academy of Allergy Immunology task force on guidelines for clinical investigation of non-bronchodilator anti-asthmatic drugs. J Allergy Clin Immunol 1986;78:489546.
  • 4
    Cockcroft DW, Murdock KY, Kirby J, Hargreave F. Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to hista-mine. Am Rev Respir Dis 1987;135:26467.
  • 5
    Dreborg S. The skin prick test. Methodological studies and clinical applications. Medical Dissertation 239, Linkoping University 1987.
  • 6
    Frølund L, Madsen F, Svendsen UG, Nielsen NH, Weeke B. Reproducibility of responsiveness to a standardized bronchial allergen provocation. R, compared to FEV, as measurement of response to provocation. Clin Allergy 1987;17:21728.
  • 7
    Frølund L, Poulsen LK, Heinig JH, Svendsen UG, Madsen F. Immunological and physical properties of allergen solutions. Effects of nebulization. Allergy 1991;46:19.
  • 8
    Løwenstein H, Lind P, Billesbølle K. Immunochemical methods for source materials. Arb Paul Ehrlich Inst 1978;78:14147.
  • 9
    Løwenstein H. Physico-chemical and immunochemical methods for the control and quality of allergenic extracts. In: First Int Paul Ehrlich Seminar. Stuttgart: Gustav Fisher Verlag, 1980;79:122.
  • 10
    Løwenstein H. Report on behalf of the International Union of Immunological Societies (IUIS) Allergen Standardization Subcommittee. Arb Paul Ehrlich Inst 1983;78:4148.
  • 11
    Matthiesen F. Standardization of allergenic extracts. Z Hautkrh 1988;63(suppl 4):54254.
  • 12
    Melillo G. Allergen inhalation challenge with a micronized freeze dried extract administered by a powder inhaler. In: MelilloG, NormanPS, MaroneG eds. Respiratory allergy. Toronto: BC Decker, 1990: 207214.
  • 13
    Nordic Council of Medicines. Registration of allergen preparations. Nordic guidelines. Uppsala: NLN, publication no. 7, 1982.
  • 14
    Nordic Council of Medicines. Common Nordic guidelines for registration of allergenic preparations. 2nd edn. Uppsala: NLN, 1989:23.
  • 15
    Norman PS. International units. In: KurthR, ed. Regulatory control and standardization of allergenic extracts. Proceedings from Fiith Int Paul Ehrlich Seminar. Stuttgart: Gustav Fisher Verlag, 1987: 17582.
  • 16
    Rosenthal R, Lassen A, Jacobsen L, Svendsen UG. Trends in the use of specific immunotherapy. In: Ring, Przybilla, ed. New trends in allergy III. Berlin: Springer Verlag, 1991.
  • 17
    Ihrkeltaub PC. Assignment of bioequivalent allergy units based on biological standardization of allergenic extracts. Proceedings from Fifth International Paul Ehrlich Seminar. Stuttgart: Gustav Fisher Verlag, 1987:1940.
  • 18
    Turkeltaub PC, Rastogi SC, Baer H, Anderson MC, Norman PS. A standardized quantitative skin test assay of allergen potency and stability: studies on the allergen dose-response curve and effect of wheal, erythema, and patient selection on assay results. J Allergy Clin Immunol 1982;70:34352.
  • 19
    Turkeltaub PC, Campbell G, Mosimann JE. Comparative safety and efficacy of short ragweed extracts differing in potency and composition in the treatment of fall hay fever. Allergy 1990;45:52846.
  • 20
    Varney VA, Gaga M, Frew AJ, Aber VR, Kay AB, Durham SR. Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs. Br Med J 1991;302:26569.
  • 21
    WHO Expert Committee on Biological Standardization. Guidelines for the preparation and establishment of reference materials and reference reagents for biological substances. WHO Tech Rep Series 1978:626.
  • 1
    Cockcroft D, Ruffin R, Dolowcch J, Hargreave E Allergen-induced increase in non-allergic bronchial reactivity. Clin Allergy 1977;7:503513.
  • 2
    MacIntyre D, Boyd G. Factors influencing the occurrence of a late reaction to allergen challenge in atopic asthmatics. Clin Allergy 1984;14:311317.
  • 3
    de Monchy JGR, Kauffman HF, Venge P et al. Broncho-alveolair eosinophilia during allergen-induced late asthmatic reactions. Am Rev Respir Dis 1985;131:3736.
  • 4
    Beasly R, Roche W, Roberts J, Holgate S. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am Rev Respir Dis 1989;139:806817.
  • 5
    Busse W, Calhoun W, Sedgwick J. Mechanism of airway inflammation in asthma. Am Rev Respir Dis 1993;147:s20s24.
  • 6
    Frew AJ, Corrigan CJ, Maestrelli P et al. T lymphocytes in allergen-induced late-phase reactions and asthma. Int Arch Allergy Appl Immunol 1989;88(1–2):6367.
  • 7
    Kay AB. Asthma and inflammation. J Allergy Clin Immunol 1991;87:893910.
  • 8
    Hsieh K. Altered interleukin-2 (IL2) production and responsiveness after hyposensitization to house dust. J Allergy Clin Immunol 1985;76:18894.
  • 9
    Van Bever H, Stevens W. Frequency and intensity of late asthmatic reactions after a bronchial challenge in asthma and rhinitis. Allergy 1989;44:471476.
  • 10
    de Monchy JGR, Kauffman HF, Venge P et al. Broncho-alveolar eosinophilia during allergen-induced late asthmatic reactions. Am Rev Respir Dis 1985;131:373.
  • 11
    Frolund L, Bonini S, Cocco G et al. Allergen extracts. Standardization of preparation for bronchial provocation tests. A position paper. Clin Exp Allergy 1993;23:702708.
  • 12
    Melillo G. Allergen inhalation challenge with a micronized freeze fried extract administered by a powder inhaler. In: Respiratory allergy. Clinical immunology. V. Z.Melillo, NormanPS, MaroneG, ed. New York: M. Dekker, 1990;23:207213.
  • 13
    Ryan G, Dolovich MB, Obminski G et al. Standardization of inhalation tests: influence of nebulizer output, particle size and method of inhalation. J Allergy Clin Immunol 1981;67:156161.
  • 14
    Cockroft DW, Killian DN, Mellon JJA et al. Bronchial reactivity to inhaled histamine: a method and clinical service. Clin Allergy 1977;7:235243.
  • 15
    Chai H, Farr RS, Froelich LA et al. Standardization of bronchial inhalation challenge procedure. J Allergy Clin Immun 1975;56:322327.
  • 16
    Balzano G, Schiano M, Cocco G. Me-far dosimeter in bronchial provocation testing with pharmacological agents. Respir New Bull 1984;26:35.
  • 17
    Frolund L, Svendsen NG, Nielsen NH et al. Bronchial allergen challenge: comparison between two different methods of provocation. Clin Allergy 1987;17:439448.
  • 18
    Pinto Mendes JA, Heureiro AC, Todo-Bom AM et al. Bronchial tests with antigen in solution and in powder form. In: Respiratory allergy. Clin immunol VII. MelilloG, NormanPS, MaroneG, ed. New York: Marcel Dekker Inc. 1990, 215219.
  • 19
    Siergiejko Z, Chyrek-Borowska S. The evaluation of the specific bronchial provocation test with powder allergens and allergen solution in allergic asthma. J Aerosol Med 1993;6(4)1287294.
  • 20
    Metzger WJ, Nugent R, Moseley P et al. Methods for bronchoalveolar lavage in asthmatic patients following bronchoprovocation and local antigen challenge. Chest 1985;87:165175.
  • 21
    Metzger WJ, Zavola D, Richerson HB. Local allergen challenge and bronchoalveolar lavage of allergic asthmatic lungs. Am Rev Respir Dis 1987;135:430.
  • 22
    Richerson HR, Metzger WJ, Hunninghake GW. Experimental models of bronchial asthma in man and in the rabbit. In: KayAB, ed. Asthma - clinical pharmacology and therapeutical progress. Oxford: Blackwell Scientific Publishers, 1986: 2332.
  • 23
    Henning R, Lanke E, Muller S et al. A method of intrasegmental allergen provocation followed by bronchoalveolar lavage in patients with pollen asthma. J Asthma 1990;28(4):251254.
  • 24
    Liu MC, Hubbard WC, Proud D et al. Immediate and late inflammatory responses to rag weed antigen challenge of peripheral airways in allergic asthmatics: cellular, mediator and permeability changes. Am Rev Respir Dis 1991;144:5158.
  • 25
    Bernstein D, Ploysongsang Y, Mittman R, Piyamahunt A, Bernstein I. The relationship between airway responsiveness measured before and after allergen-induced late asthmatic response. Chest 1992;101(2):43741.
  • 26
    Clement J, Landser F, Van de Woestijne K. Total resistance and reactance in patients with respiratory complaints with and without airways obstruction. Chest 1983;2:215220.
  • 27
    Gimeno F, Van der Weele L, Koeter G, de Monchy J, Altena R. Variability of forced oscillation (Siemens Siregnost FD 5) measurements of total respiratory resistance in patients and healthy subjects. Ann Allergy 1993;71:5660.
  • 28
    Weller MS, Weller FR, Rijssenbeek-Nouwens LHM, de Monchy JGR. Time course of the later bronchial reaction after allergen challenge. Allergy 1992;47:19.
  • 29
    Durham SR., Kay AB. Eosinophils, hyperreactivity and late-phase asthmatic reactions. Clin Allegy 1985;15:41118.
  • 30
    Flick W, Sedwick J, Busse W. The appearance of hypodense eosinophils in antigen-dependent late-phase asthma. Am Rev Respir Dis 1989;139:14011406.
  • 31
    Van Bever H, Moens MM, Bridts CH et al. Effect of a bronchial provocation test with house-dust mite on blood eosinophilia, eosinophil cationic protein, soluble inter-leukin-2 receptor, and interleukin-6 in asthmatic children. Allergy 1993;48(6):4439.
  • 32
    Metzger W, Richerson H, Wasserman S. Generation and partial characterization of eosinophil chemotactic activity and neutrophil chemotactic activity during early and late-phase asthmatic response. J Allergy Clin Immunol 1986;78:28290.
  • 33
    Hakansson L, Rak S, Dahl R, Venge P. The formation of eosinophil and neutrophil chemotactic activity during a pollen season and after allergen challenge. J Allergy Clin Immunol 1989;83:933939.
  • 34
    de Monchy J, Keyzer J, Kauffman H, Beaumont F, de Vries K. Histamine in late asthmatic reactions following house dust mite inhalations. Agent Actions 1985;16:252255.
  • 35
    Holgate S, Wilson J, Howarth FP. Insights into airway inflammation by endobronchial biopsy. Am Rev Respir Dis 1992;145:S2S6.
  • 36
    Hamid Q, Azzawi M, Ying S et al. Expression of messenger RNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest 1991;87(5):15411546.
  • 37
    Broide DH, Lotz M, Cuomo AJ, Cobum DA, Federman EC, Wasserman SI. Cytokines in symptomatic asthma airways. J Allergy Clin Immunol 1992;89:95867.
  • 38
    Robinson D, Hamid Q, Bentley A, Ying S, Kay A, Durham S. Activation of CD4+ T cells, increased Th2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J Allergy Clin Immunol 1993;92:31324.
  • 39
    Von Essen S, Robbins R, Spurzem J, Thompson A, McGranaghan S, Rennard S. Bronchoscopy with bronchoalveolar lavages causes neutrophil recruitment to the lower respiratory tract. Am Rev Respir Dis 1991;141:848854.
  • 40
    Clinical guidelines and indications for bronchoalveolar lavage (BAL): Report of the European Society of Pneumology Task Group on BAL. Eur Respir J 1990;3(8):93776.
  • 1
    Melillo G, Cocco G, D'Amato G. Bronchial provocation tests in etiologic diagnosis of asthma. Broncho-pneumolo-gie 1979;29:329336.
  • 2
    SEPCR Working GroupBronchial Hyperreactivity. Guidelines for standardization of bronchial challenges with (nonspecific) bronchoconstricting agents Bull Eur Physiopathol Respir 1983;19:495514.
  • 3
    Hargreave FE, Dolovich J, Boulet LP. Inhalation provocation tests Semin Respir Med 1983;42:248.
  • 4
    Burge PS. Aerosol challenge in lung disease. In: ClarkeSW, PaivaD, ed. Aerosols and the lung. London: Butterworths, 1984: 225240.
  • 5
    Melillo G. Allergen inhalation challenge with a micronized freeze fried extract administered by a powder inhaler. In: MelilloG, NormanPS, MaroneG, ed. Respiratory allergy, Clinical immunology, V 2. New York: M. Dekker, 1990;23:207213.
  • 6
    Herxheimer H. Bronchial hypersensitization and hypo-sensitization in man. Int Arch Allergy Immunol 1951;2:4044.
  • 7
    Cormell JT. Quantitative intranasal pollen challenges. III. The priming effect in allergic rhinitis. J Allergy 1969;43:3337.
  • 8
    Kelly JF, Fish JE, Peterman VI. Effect of environmental exposure on bronchial sensitivity to antigen. Int Arch Allergy Immunol 1979;59:130134.
  • 1
    Altmann DG, Bland JM. Measurement in medicine: The analysis of methods comparison studies. Statistician 1983;32:30717.
  • 2
    Bland JM, Altmann DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;30710.
  • 3
    Bruce CA, Rosenthal RR, Lichtenstein LM, Norman PS. Diagnostic tests in ragweed-allergic asthma. A comparison of direct skin-tests, leukocyte histamine release, and quantitative bronchial challenge. J Allergy Clin Immunol 1974;53:2309.
  • 4
    Cartier A, Thomson NC, Frith PA, Roberts R, Tech M, Hargreave FE. Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber. J Allergy Clin Immunol 1982;70:17077.
  • 5
    Chinn S. Repeatability and method comparison. Thorax 1991;46:45456.
  • 6
    Chinn S. Ranges, confidence intervals, and related quantities: What they are and when to use them. Thorax 1991;46:39193.
  • 7
    Cockcroft DW, Ruffin RE, Frith PA et al. Determinants of allergen induced asthma: dose of allergen, circulating IgE antibody concentration, and bronchial responsiveness to histamine. Am Rev Respir Dis 1979;120:105358.
  • 8
    Cockcroft DW, Ruffin RE, Dolovich J, Hargreave FE. Allergen-induced increase in non-allergic bronchial reactivity. Clin Allergy 1977;7:50313.
  • 9
    Crimi E, Brancatisano M, Villa G, Brusasco V. Dual asthmatic reactions to inhaled Dematophagoides pteronys-sinus: reproducibility and antagonism by cromolyn sodium. Ann Allerev 1986;56:1836.
  • 10
    Eiser NM, MacRae KD, Guz A. Evaluation and expression of bronchial provocation tests. Bull Eur Physiopathol Respir 1981;17:42740.
  • 11
    Fish JE, Kelly JF. Measurements of responsiveness in bronchoprovocation testing. J Allergy Clin Immunol 1979;64:59296.
  • 12
    Frølund L, Madsen F, Scharling B, Heinig JH, Svendsen UG. Bronchial allergen challenge: dose versus concentration. The effect of 2 equivalent doses of allergen administered by different dosing regimes on the magnitude of the early asthmatic response. Clin Exp Allergy 1992;22:21925.
  • 13
    Frølund L, Madsen F, Svendsen UG, Nielsen NH, Weeke B. Reproducibility of responsiveness to a standardized bronchial allergen provocation. R1 compared to FEV, as measurement of response to provocation. Clin Allergy 1987;17:21728.
  • 14
    Frølund L, Madsen F, Svendsen UG, Weeke B. Reproducibility of a standardized bronchial allergen test. Allergy 1986;41:3036.
  • 15
    Hargreave FE, Dolovich J, Robertson DG, Kerigan AT. The late asthmatic responses. Can Med Assoc J 1974;110: 41524.
  • 16
    Haugaard L, Iversen M, Dahl R. A comparative study of four different bronchial challenge tests. Allergy 1992;47:13842.
  • 17
    Kopferschmitt-Kubler MC, Bigot H, Pauli G. Allergen bronchial challenge tests: Variability and reproducibility of the early response. J Allergy Clin Immunol 1987;80:73040.
  • 18
    Lai CKW, Twentymann OP, Holgate ST. The effect of an increase in inhaled allergen dose after rimiterol hydro-bromide on the occurrence and magnitude of the late asthmatic response and the associated change in nonspecific bronchial responsiveness. Am Rev Respir Dis 1989;140:91723.
  • 19
    Lai CKW, Beasley R, Holgate ST. The effect of an increase in inhaled allergen dose after terfenadine on the occurrence and magnitude of the late asthmatic response. Clin Exp Allergy 1989;19:20916.
  • 20
    Lowhagen O, Lindholm NB. Standardized allergen provocation test. Allergy 1980;35:34956.
  • 21
    Machado L, Stdlenheim G. Factors influencing the occurrence of late bronchial reactions after allergen challenge. Allergy 1991;45:26874.
  • 22
    Moscato G, Dellabianca A, Paggiaro P, Bertoletti R, Corsoco A, Perfetti L. Peak expiratory flow monitoring and airway response to specific bronchial provocation tests in asthmatics. Monaldi Arch Chest Dis 1993;48;1: 2328.
  • 23
    Rasmussen JB. Late airway response increases at repeat allergen challenge. Allergy 1991;46:41926.
  • 24
    Reed C, Townley RG. Asthma: classification and patho-genesis. In: MiddletonEJr, ReedCE, EllisEF, ed. Allergy: principles and practice. 2nd edn. St Louis: Mosby, 1983;81131.
  • 25
    Rosenthal RR, Normann PS, Summer WR. Bronchoprovocation: effect on priming and desensitization phenomena in the lung. J Allergy Clin Immunol 1975;56:33846.
  • 26
    Ruffin RE, Cockroft W, Hargreave FE. A comparison of the protective effect of fenoterol and Sch 1000 on allergen-induced asthma. J Allergy Clin Immunol 1978;61:4247.
  • 27
    Tamura G, Mue S, Ishihara T, Takishima T. The single exposure method for inhalation challenge with allergen. J Allergy Clin Immunol 1985;75:4754.
  • 28
    Tiffeneau R. Examen pulmonaire de l'asthmatique. In: Masson, Cie, ed. Déduction diagnostiques pronostiques et thérapeutiques. Paris 1957;1245.
  • 29
    Tiffeneau R. Hypersensibilité cholinergo-histaminique pulmonaire de l'asthmatique. Acta Allergol 1958;13(suppl 5):187221.
  • 30
    Townley RG, Dennis M, Itkin JM. Comparative action of acetyl-beta-metacholine, histamine, and pollen antigens in subjects with hay fever and patients with bronchial asthma. J Allergy 1965;36:121.
  • 31
    Aas K. Bronchoprovocative tests (BTP) in clinical and experimental allergy. AM Allergy 1974;33:32024.
  • 1
    Cockcroft DW, Ruffin RE, Frith PA et al. Determinants of allergen-induced asthma; dose of allergen, circulating IgE antibody concentration and bronchial responsiveness to inhaled histamine. Am Rev Respir Dis 1979;12010538.
  • 2
    Crimi E, Brusasco V, Losurdo E, Crimi E Predictive accuracy of late asthmatic reaction to Dermatophagoides pteronyssinus. J Allergy Clin Immunol 1986;78:90813.
  • 3
    Killian D. Factors in allergen induced asthma: relevance of intensity of the airway allergic reaction and non-specific bronchial reactivity. Clin Allergy 1976;2:61922.
  • 4
    Bryant DH, Burns MW. Bronchial histamine reactivity: its relationship to reactivity of the bronchi to allergens. Clin Allergy 1976;6:52332.
  • 5
    Popa V, Garfield M. Immunologic and pharmacologic determinants of bronchial responses to inhaled ragweed. J Allergy Clin Immunol 1979;63:1412.
  • 6
    de Kock MA. Mechanism of bronchial obstruction in man. In OrieNGM, van derLendeR, ed. Bronchitis III, Assen: Royal van Gorcum, 1970:300311.
  • 7
    Dimeo MJ. Tnreshold concentration of ozone causing an increase in bronchial reactivity in humans and adaption with repeated exposures. Am Rev Respir Dis 1981;124:245.
  • 8
    Drazen J, Austen W. Atropine modification of the pulmonary effect of chemical mediators in the guinea pig. J Appl Physiol 1975;38:834.
  • 9
    Bruce CA, Rosenthal RR, Lichtenstein LM, Norman PS. Diagnostic tests in ragweed-allergic asthma: a comparison of direct skin tests, leukocyte histamine release and quantitative bronchial challenge. J Allergy Clin Immunol 1974;53:2319.
  • 10
    Ankin MG, Peterman VI, Fish JE. Physiologic responses to inhaled antigen in subjects with hayfever and asthma. J Allergy Clin Immunol 1979;63:14950.
  • 11
    Altounyan REC. Changes in histamine and atropine responsiveness as a guide to diagnosis and evaluation of therapy in obstructive airways disease. In: PepysJ, FranklandAW, ed. Disodium cromoglycate in allergic airways disease. London: Butterworths, 1969: 4753.
  • 12
    Cartier A, Thomson NC, Frith PA, Roberts R, Hargreave FE. Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber. J Allergy Clin Immunol 1982;70:1707.
  • 13
    Boulet LP, Cartier A, Thomson NC, Roberts RS, Dolovich J, Hargreave FE. Asthma and increases in non-allergic bronchial responsiveness from seasonal pollen exposure. J Allergy Clin Immunol 1983;71:399406.
  • 14
    Sotomayor H, Badier M, Vervolet D, Orehek J. Seasonal increase of carbachol airways responsiveness in patients allergic to grass pollen. Am Rev Respir Dis 1984;130:568.
  • 15
    Cockcroft DW, Ruffin RE, Dolovich J, Hargreave FE. Allergen induced increase in non-allergic bronchial reactivity. Clin Allergy 1977;7:50313.
  • 16
    Wegner CD, Torcellini C, Clarke CC, Letts LG, Gundel RH. Effects of single and multiple inhalations of antigen on airway responsiveness in monkeys. J Allergy Clin Immunol 1991;87:83541.
  • 17
    Tanaka DT, Ando RE, Larsen GL, Irvin CG. Cholinergic mechanisms involved with histamine hyperreactivity in immune rabbit airways challenged with ragweed antigen. Am Rev Respir Dis 1991;144:7075.
  • 18
    Platts Mills TAE, Tovey ER, Mitchell EB, Mozzorro W, Noch P, Wilkins SR. Reduction of bronchial hyperreactivity during prolonged allergen avoidance. Lancet 1982;ii:6758.
  • 19
    Murray AB, Ferguson AC. Dust-free bedrooms in the treatment of asthmatic children with house dust or house mite allergy: a controlled trial. Pediatrics 1983;71:41822.
  • 20
    Lowhagen O, Rak S. Modification of bronchial hyperreactivity after treatment with sodium cromoglycate during pollen season. J Allergy Clin Immunol 1985;75:4067.
  • 21
    Cockcroft DW, Cotton DJ, Nink JT. Nonspecific bronchial reactivity after exposure to western red cedar. Am Rev Respir Dis 1977;119:50510.
  • 22
    Chan-Yeung M. Fate of occupational asthma: a follow-up study of patient with occupational asthma due to western red cedar. Am Rev Respir Dis 1977;116:102331.
  • 23
    Hargreave FE, Frith PA, Dolovich M et al. Allergen induced airway responses and relationships with nonspecific reactivity. In HargreaveFE, ed. Airway reactivity: mechanisms and clinical relevance. Astra publ., 1980:145150.
  • 24
    Popa V. Respiratory allergy to ragweed: correlation of bronchial responses to allergen and bronchial responses to histamine and circulating immunoglobulin E. J Allergy Clin Immunol 1980;65:389.
  • 25
    Popa V. Correlation between skin test and inhalation test results. In: WeissEB, SegalMS, SteinM, ed. Bronchial asthma. Boston: Little Brown and Co., 1985: 387400.
  • 26
    Melillo G, Cocco G, Schiano M et al. Relationship between atopy and non-specific bronchial hyperresponsiveness in asthma. In: OlivieriD, BiancoS, ed. Airway obstruction and inflammation. Progr Resp Basel: Karger 1990;24:151155.
  • 27
    Murphy KR, Wilson MC, Irvin CG et al. The requirement for polymorphonuclear leukocytes in the late asthmatic response and heightened airway reactivity in an animal model. Am Rev Respir Dis 1986;134:628.
  • 28
    O'Byrne PM, Dolovich M, Dirks R, Roberts RS, Newhousa MJ. Lung epithelial permeability: relation to non specific airway responsiveness. J Appl Physiol 1984;57:7784.
  • 29
    Metzger WJ, Hunninghake GW, Richardson HG. Late asthmatic responses: inquiry into mechanisms and significance. Clin Rev Allergy 1985;3:14565.
  • 30
    de Monchy JGR, Kauffman HF, Venge P et al. Broncho-alveolar eosinophilia during allergen-induced late asthmatic reactions. Am Rev Respir Dis 1985;131:3736.
  • 31
    Brusasco V, Crimi E, Gianiorio P, Lantero S, Rossi GA. Allergen induced increase in airway responsiveness and inflammation in mild asthma. J Appl PhysioI 1990;69:220914.
  • 32
    Booij-Noord H, de Vries K, Sluiter HJ, Orie NGM. Late bronchial obstructive reaction to experimental inhalation of house dust extract. Clin Allergy 1972;2:4361.
  • 33
    Cartier A, Thomson NC, Frith PA, Roberts R, Hargreave FE. Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and changes in airway caliber. J Allergy Clin Immunol 1982;70:1707.
  • 34
    Durham SR, Graneek BJ, Hawkins R, Newman Taylor AJ. The temporal relationship between increase in airway responsiveness to histamine and late asthmatic responses induced by occupational agents. J Allergy Clin Immunol 1987;79398406.
  • 35
    Durham SR, Craddock CF, Cookson WO, Benson MK. Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses. J Allergy Clin Immunol 1988;82:76470.
  • 36
    Aalbers R, Kaufman HI, Koeter GH et al. Dissimilarity in methacholine and adenosine 5′-monophosphate responsiveness 3 and 24 h after allergen challenge. Am Rev Respir Dis 1991;144:3527.
  • 37
    Wenzel SE, Fowler AA, III, Schwartz LB. Activation of pulmonary mast cells by bronchoalveolar challenge. Am Rev Respir Dis 1988;137:10028.
  • 38
    Crimi E, Chiaramondia M, Milanese M, Rossi GA, Brusasco V. Increased numbers of mast cells in bronchial mucosa after the late-phase asthmatic response to allergen. Am Rev Respir Dis 1991;144:12826.
  • 39
    Abraham WM, Sielczak MW, Warner A et al. Cellular markers of inflammation in the airways of allergic sheep with and without allergen-induced late responses. Am Rev Respir Dis 1988;138:156571.
  • 40
    Diaz P, Conzalez MC, Galleguillos FR et al. Leukocytes and mediators in bronchoalveolar lavage during allergen-induced late-phase asthmatic reactions. Am Rev Respir Dis 1989;139:13839.
  • 1
    Hargreave FE, Woolcock AJ. Airway responsiveness, measurement and interpretation. Astra Pharmaceutical Publications Canada Ltd., 1983.
  • 2
    Chai H, Farr RS, Froehlich LA et al. Standardization of bronchial inhalation challenge procedures. J Allergy Clin Immunol 1975;56:323.
  • 3
    Curry JJ. The action of histamine on the respiratory tract in normal and asthmatic subjects. J Clin Invest 1946;35:785791.
  • 4
    Cockcroft DW, Wian DN, Mellon JJ, Hargreave FJ. Bronchial reactivity to inhaled histamine. A method and clinical survey. Clin Allergy 1977;7:23543.
  • 5
    Bennett JB, Davies RJ. A comparison of histamine and methacholine bronchial challenges using the De Vibiss 646 nebuliser and the Rosenthal French dosimeter. Br J Dis Chest 1987;81:252259.
  • 6
    Juniper EF, Frith PA, Dunnett C et al. Reproducibility and comparison of responses to inhaled histamine and methacholine. Thorax 1978;33:705710.
  • 7
    Egg CJ, Jhalli N, Herdman MJ et al. The daily variability of bronchial responsiveness to methacholine. Eur Respir J 1990;3:867871.
  • 8
    Mygind N. Nasal allergy. 2nd edn. London: Blackwell Scientific Publications, 1979: 219.
  • 9
    Fleming DM, Crombie DC. Prevalence of asthma and hay fever in England and Wales. Br Med J 1987;294:279283.
  • 10
    Borum P. Nasal methacholine challenge: a test for the measurement of nasal reactivity. J Allergy Clin Immunol 1979;63:253.
  • 11
    Okuda M, Ohtsuka H, Sakagudin K et al. Nasal histamine sensitivity in allergic rhinitis. Ann Allergy 1983;51:51.
  • 12
    Pelikan Z. Late nasal response (LNR) - its clinical characteristics, feature, and possible mechanism(s). In: DorschW, ed. Late-phase allergic reactions Boca Raton, FL: CRC Press, 1990:111155.
  • 13
    Blackley CH. Experimental researches on the causes and nature of catarrhus aestivus London: Baillière Tindall, 1873.
  • 14
    Aschan G, Drettner. Nasal obstruction at provocation experiments in patients with hay fever. Acta Otolaryngol (Stockh) suppl 1191.
  • 15
    Wihl J-A. Methods for assessing nasal reactivity. Eur J Respir Dis 1983;64(suppl 128):175179.
  • 16
    Huggins KG, Brostoff J. IgE antibodies in allergic patients with negative skin tests. Lancet 1975;2:146.
  • 17
    Pelikan Z. Late and delayed responses of the nasal mucosa to allergen challenge. Ann Allergy 1978;41:37.
  • 18
    Pelikan Z, Feenstra L, Barree GOE Response of the nasal mucosa to allergen challenge measured by two different methods of rhinomanometry. Ann Allergy 1977;38:263.
  • 19
    Blainey AD, Coe MJ, Ollier S, Davies RJ. Methacholine provocation tests in grain workers. Thorax 1983;38:220 (abstr).
  • 20
    Phillips MJ, Ollier S, Davies RJ. Use of anterior rhinomanometry in nasal provocation challenges with allergen and evaluation of the effects of ketotifen, clemastine and sodium cromoglycate on these responses. Respiration 1980;39(suppl):2631.
  • 21
    Pelikan Z, Pelikan-Filipek M. The effects of disodium cromoglycate and beclomethasone dipropionate on the immediate response of the nasal mucosa to allergen challenge. Ann Allergy 1982;49:20.
  • 22
    Pelikan Z. Rhinitis and secretory otitis media: a possible role of food allergy. In: BrostoffJ, ChallcombeSJ, ed. Food allergy and intolerance. 1st edn. London: Baillière Tmdall, 1987:467.
  • 23
    Davies RJJ, Blainey AD. Evaluation of treatment of house dust mite allergy in perennial rhinitis In: KerrJW, GandertonMA, ed. Proceedings of the XIth International Congress of Allergology and Clinical Immunology 1983. Basingstoke: Macmillan, 291295.
  • 24
    Pelikan Z. Role of nasal allergy in chronic maxillary sinusitis - diagnostic values for nasal challenge with allergen. J Allergol Clin Immunol 1990;86:484.
  • 25
    Andri L, Senna GE, Betelli C et al. Specific nasal provocation test with allergens in powder form proves a reliable and reproducible technique. Allergy 1992;47:243 (abstr).
  • 26
    Okuda M. Response of the human nasal mucous membrane to anti-human IgE serum. Arch Otorhinolaryngol 1975;211:2533.
  • 27
    Davies RJ, Corrado OJ. Diagnostic tests - challenge tests: Oral, nasal and bronchial. In: LessofMH, ed. Allergy. London: Wiley & Sons Ltd, 1984.
  • 28
    Naclerio RM, Meier HL, Kagey-Sobotka A et al. Mediator release after nasal airway challenge with allergen. Am Rev Respir Dis 1983;128:597602.
  • 29
    Bouquet J, Lebel B, Dhivert H et al. Nasal challenge with pollen grains, skin prick tests and specific IgE in patients with grass pollen allergy. Clin Allergy 1987;17:529536.
  • 30
    Connell JT. Quantitative intranasal pollen challenge III. The priming effect in allergic rhinitis J Allergy 1969;43:3342.
  • 31
    Schiano M, Cocco G, Balzano G, D'Agostino F, Melillo G. Nasal provocation with allergens in powder. Xhe XIIIth Congress of the Eur Acad Allergol & Clin Immunol, Budapest, May 5–10, 1986 (Hungary). Workshop on “The use of allergen in powder form for provocation tests and for local immunotherapy in allergic asthma”.
  • 32
    Mygind N, Thomsen J. ICI 74917. A new anti-allergic drug administered by pressurised aerosol. Acta Allergol (Kgh) 1975;30:298.
  • 33
    Knowles GK, Townsend P, ber Warwick M. A standardised filter paper technique for assessing nasal secretory activity. Clin Allergy 1981;11:287292.
  • 34
    Eiser N. The hitch-hiker's guide to nasal patency. Respir Med 1990;84:179183.
  • 35
    Taylor G, MacNeil AR, Freed DLJ. Assessing the degree of nasal patency by measuring peak expiratory flow rate through the nose. J Allergy Clin Immunol 1973;52:193198.
  • 36
    Gleeson MJ, Youlton LJF, Skelton DM et al. Assessment of nasal airway patency: a comparison of four methods. Clin Otolaryngol 1986;11:99107.
    Direct Link:
  • 37
    Cook N. Pre-seasonal local nasal desensitisation in hay fever. J Laryngol Otol 1974;88:1169.
  • 38
    Eccles R. Rhinimanometry and nasal challenge. In: Mackay, ed. Rhinitis: mechanisms and management. London: Royal Society of Medicine SeMces Ltd., 1989.
  • 39
    Clement PAR. Committee report on standardization of rhinomanometry. Rhinology 1984;22:151155.
  • 40
    Hey EN, Price JF. Nasal conductance and effective airway diameter. J Physiol 1982;330:429437.
  • 41
    Broms P, Johnson B, Lamm CJ. A universal way to evaluate the curve in rhinomanometry. Acta Otolaryngol 1979;suppl 360:2223.
  • 42
    Cole P, Fasteng O, Niinimaa V. Computer-aided rhinomanometry. Acta Otolaryngol 1980;90:139142.
  • 43
    Kern EB. Committee report on the standardization of rhinomanometry. Rhinology 1981;19:231236.
  • 44
    Cole PH, Havas TH. Nasal resistance to respiratory airflow: a plethysmographic alternative to the face mask. Rhinology 1987;25:159.
  • 45
    Jackson AC et al. Airway geometry by analysis of acoustic pulse response measurements. J Appl Physiol 1977;43:523536.
  • 46
    Eerdel D, Gant R, Huber B et al. The simplified oscillation method for measuring nasal resistance during provocation with allergens. Clin Allergy 1981;11:385393.
  • 47
    Shelton DM, Pertuze J, Gleeson MJ et al. Comparison of oscillation with three other methods for measuring nasal airways resistance. Respir Med 1990;84:101106.
  • 48
    Druce HM, Bonner RF, Patow C et al. Response of nasal blood flow to neurohormones as measured by laser-Doppler velocimetry. J Appl Physiol Respir Environ Exerc Physiol 1984;57:1276.
  • 49
    Olson P. A comparison between the 133Xe washout and laser-Doppler techniques for estimation of nasal mucosal blood flow in humans. Acta Otolaryngol (Stockh) 1986;102:106.
  • 50
    Ferguson H, Thomas KE. Letter to the editor. Respir Med 1990;84:419433.
  • 51
    Pelikan Z. The late nasal response, its clinical and immuno-logic features, possible mechanisms and pharmacologic modulation. Thesis. Free University in Amsterdam, 1996.
  • 52
    Pelikan Z, Pelikan-Filipek M. A new disease - a nasal form of pigeon breeder's disease. Allergy 1983;38:309.
  • 53
    Pelikan Z. The effects of disodium cromoglycate and beclomethasone dipropionate on the late nasal mucosa response to allergen challenge. Ann Allergy 1982;49:200.
  • 54
    Pelikan Z, Pelikan-Filipek M. Non-specific hyperreactivity (N-SH) and basic types of nasal response to allergen challenge in rhinitis patients. J Allergy Clin Immunol 1992;89:179 (Abstr 140).
  • 55
    Pelikan Z, Pelikan-Filipek M. Cytological changes in the nasal secretions during the late nasal response (LNR). J Allergy Clin Immunol 1989;83:1068.
  • 56
    Ferguson H, Davies RJ. Late phase nasal reactions -reviewed and revisited. Respir Med 1990;85:3.
  • 57
    Davies RJ. Mast cells in the nose. Cambridge: BSACI, 1989.
  • 58
    Lozewicz S, Gomez E, Claque JE et al. Allergen-induced changes in the nasal mucous membrane in seasonal allergic rhinitics: effect of nedocromil sodium. J Allergy Clin Immunol 1990;(85) 1 part 1:125131.
  • 59
    Pelikan Z, Pelikan-Filipek M. Cytological changes in the nasal secretions during the immediate nasal response (INR). J Allergy Clin Immunol 1988;82:1103.
  • 60
    Frew AJ, Kay AB. Eosinophils and T-lymphocytes in late phase allergic reactions. J Allergy Clin Immunol 1990;85:533539.
  • 61
    Walden S, Proud D et al. Experimentally induced nasal allergic responses. J Allergy Clin Immunol 1988;81:940949.
  • 62
    Howarth P. Allergic rhinitis: a rational choice of treatment. Respir Med 1989;83:179188.
  • 63
    Alam R et al. Development of a new technique for recovery of cytokines from inflammatory sites in situ. J Immunol Methods 1992;155:2529.
  • 64
    Thomas K, Greenwood L, Murrant N et al. The effects of topical fluticasone propionate on allergen-induced immediate nasal airways response and eosinophil activation: preliminary results. Respir Med 1990;84:33.
  • 65
    Lindqvist N, Balle VH, Karma P et al. Long term safety of budesonide nasal aerosol in perennial rhinitis. Allergy 1986;41:179186.
  • 1
    Peshkin MM. A dry pollen ophthalmic test in pollen asthma and hay fever patients negative to cutaneous tests. J Allergy 1931;3:20.
  • 2
    Abram LE. An evaluation of conjunctival testing in extrinsic respiratory allergy. J Allergy 1949;20:66.
  • 3
    Tuft L, Ettelson L, Gupta K, Krueger C. Eye tests with inhalant allergens. Their feasibility, indications and clinical value. J Allergy 1959;30:492.
  • 4
    Bonini S, Bonini S, Vecchione A, Naim DM, Mansmith MR, Balsano F. Inflammatory changes in conjunctival scrapings after allergen provocation in humans. J Allergy Clin Immumol 1988;62:462.
  • 5
    Friedlander MH. Conjunctival provocation tests: a model of human ocular allergy. Trans Am Ophthalmol Soc 1989;87:577.
  • 6
    Stenius-Aarniala BSM, Malberg CHO, Holopainen EEA. Relationship between the results of bronchial, nasal and conjunctival provocations tests in patients with asthma. Clin Allergy 1978;8:403.
  • 7
    Malmberg CHO, Holopainen EEA, Stenius-Aarniala BSM. Relationship between nasal and conjunctival tests in patients with allergic rhinitis. Clin Allergy 1978;8:397.
  • 8
    Vanto T, Viander M, Koivikko A. Skin prick test in the diagnosis of dog dander allergy. A comparison of different extracts with clinical history, provocation tests and RAST. Clin Allergy 1980;10:121.
  • 9
    Tuft L. The value of eye tests with inhalant allergens. A clinical study. Ann Allergy 1967;25183.
  • 10
    Leonardi A, Fregona A, Gismondi M, Daniotti E, Carniel G, Secchi AG. Correlation between conjunctival provocation test (CPT) and systemic allergometric tests in allergic conjunctivitis. Eye 1990;4:760.
  • 11
    Liotet S, Warnet VN, Arrata M. Lacrimal immunoglobulin E and allergic conjunctivitis. Ophthalmologica 1986;186:31.
  • 12
    Ballow M, Mendelson L. Specific immunoglobulin E antibodies in tear secretions of patients with vernal conjunctivitis. J Allergy Clin Immunol 1980;66:112.
  • 13
    Moller C, Elsayed S. Seasonal variation of the conjunctival provocation test, total and specific IgE in children wit birch pollen allergy. Int Arch Allergy Immunol 1990;92:306.
  • 14
    Bonini S, Bonini S, Berruto A et al. Conjunctival provocation test as a model for the study of allergy and inflammation in humans. Int Arch Allergy Immunol 1989;88:144.
  • 15
    Proud D, Sweet J, Stein P et al. Inflammatory mediator release on conjunctival provocation of allergic subjects with allergen. J Allergy Clin Immunol 1990;85:896.
  • 16
    Irani AA, Butrus SI, Tabbara KF, Schwartz LB. Human conjunctival mast cells. Distribution of MTc and MCtc in vernal conjunctivitis and giant papillary conjunctivitis. J Allergy Clin Immunol 1990;86:34.
  • 17
    Abelson MB, Chambers WA, Smith LM. Conjunctival allergen challenge. A clinical approach to studying allergic conjunctivitis. Arch Ophthalmol 1990;108:84.
  • 18
    Bonini S, Bonini S, Bucci MG et al. Allergen dose response and late symptoms in a human model of ocular allergy. J Allergy Clin Immunol 1990;86:867.
  • 19
    Moller C, Bjorksten B, Nilsson G, Dreborg S. The precision of the conjunctival provocation test. Allergy 1984;39:37.
  • 20
    Abelson MB, Baird RS, Allansmith MR. Tear histamine levels in vernal conjunctivitis and other ocular inflammations. Ophthalmology 1980;87:812.
  • 21
    Stegman R, Miller D. A human model of allergic conjunctivitis. Arch Ophthalmol 1975;93:1354.
  • 22
    Mikuni I. The use of provocation tests for the diagnosis of allergic conjunctivitis caused by Japanese cedar. Tokai J Exp Clin Med 1980;4:35.