Prevalence of asthma, allergic rhinoconjunctivitis and allergic sensitization in Mongolia
Article first published online: 16 AUG 2005
Volume 60, Issue 11, pages 1370–1377, November 2005
How to Cite
Viinanen, A., Munhbayarlah, S., Zevgee, T., Narantsetseg, L., Naidansuren, Ts., Koskenvuo, M., Helenius, H. and Terho, E. O. (2005), Prevalence of asthma, allergic rhinoconjunctivitis and allergic sensitization in Mongolia. Allergy, 60: 1370–1377. doi: 10.1111/j.1398-9995.2005.00877.x
- Issue published online: 3 OCT 2005
- Article first published online: 16 AUG 2005
- Accepted for publication 9 March 2005
- asthma hygiene hypothesis;
Background: Studies in countries, such as Mongolia, which are in transition from farming to industrial society permit evaluation of the impact of environmental change on atopic diseases.
Methods: In the screening study, questionnaire data were obtained from 9453 subjects aged 10–60 years. In the clinical study, a subsample of 869 subjects (participation rate 50.0%) was examined. A questionnaire-based interview, clinical examination, skin prick tests, spirometry and bronchodilation test or methacholine challenge test were used to define the clinical diagnoses. The prevalences of atopic diseases were evaluated at the population level using two-phase data and sampling weights.
Results: The prevalences of asthma, allergic rhinoconjunctivitis and allergic sensitization with 95% confidence intervals were 1.1% (0.3–2.0%), 9.3% (4.0–14.6%) and 13.6% (7.4–19.9%) in Mongolian villages, 2.4% (1.4–3.5%), 12.9% (8.2–17.7%) and 25.3% (17.1–33.6%) in rural towns and 2.1% (1.3–3.0%), 18.4% (13.3–23.4%) and 31.0% (24.5–37.5%) in Ulaanbaatar city, respectively. The prevalence of allergic rhinoconjunctivitis (P = 0.02) and allergic sensitization (P = 0.003) increased significantly with increasing urbanization.
Conclusions: The prevalences of atopic diseases were low in rural Mongolia and increased with increasing urbanization suggesting that rural living environment protects against atopy.