• 1
    Zielhuis GA, Rach GH, Van Den Broek P. The occurrence of otitis media with effusion in Dutch pre-school children. Clin Otolaryngol 1990;15: 147153.
  • 2
    Klein JO. The burden of otitis media. Vaccine 2000;19(Suppl. 1):S2S8.
  • 3
    Rosenfeld RM, Culpepper L, Doyle KJ, Grundfast KM, Hoberman A, Kenna MA et al. Clinical practice guideline: otitis media with effusion. Otolaryngol Head Neck Surg 2004;130(Suppl. 5): S95S118.
  • 4
    Fireman P. Otitis media and eustachian tube dysfunction: connection to allergic rhinitis. J Allergy Clin Immunol 1997;99: S787S797.
  • 5
    Skoner DP. Complications of allergic rhinitis. J Allergy Clin Immunol 2000;105: S605S609.
  • 6
    Lack G. Pediatric allergic rhinitis and comorbid disorders. J Allergy Clin Immunol 2001;108(Suppl. 1):S9S15.
  • 7
    Smirnova MG, Birchall JP, Pearson JP. The immunoregulatory and allergy-associated cytokines in the aetiology of the otitis media with effusion. Mediators Inflamm 2004;13: 7588.
  • 8
    Jang CH, Kim YH. Demonstration of RANTES and eosinophilic cataionic protein in otitis media with effusion with allergy. Int J Pediatr Otorhinolaryngol 2003;67: 531533.
  • 9
    Hurst DS, Weekley M, Ramanarayanan MP. Evidence of possible localized specific immunoglobulin E production in middle ear fluid as demonstrated by ELISA testing. Otolaryngol Head Neck Surg 1999;121: 224230.
  • 10
    Hurst DS, Venge P. Evidence of eosinophil, neutrophil, and mast-cell mediators in the effusion of OME patients with and without atopy. Allergy 2000;55: 435441.
  • 11
    Borge P. Atopy and secretory otitis media. Immunological studies and responses to topical corticosteroid therapy. J Laryngol Otol 1983;97: 117129.
  • 12
    Corey JP, Adham RE, Abbass AH, Seligman I. The role of IgE-mediated hypersensitivity in otitis media with effusion. Am J Otolaryngol 1994;15: 138144.
  • 13
    Saim A, Saim L, Saim S, Ruszymah BH, Sani A. Prevalence of otitis media with effusion amongst pre-school children in Malaysia. Int J Pediatr Otorhinolaryngol 1997;41: 2128.
  • 14
    Caffarelli C, Savini E, Giordano S, Gianlupi G, Cavagni G. Atopy in children with otitis media with effusion. Clin Exp Allergy 1998;28: 591596.
  • 15
    Mogi G, Tomonaga K, Watanabe T, Chaen T. The role of type I allergy in secretory otitis media and mast cells in the middle ear mucosa. Acta Otolaryngol Suppl 1992;493: 155163.
  • 16
    Mion O, De Mello Jr JF, Lessa MM, Goto EY, Miniti A. The role of rhinitis in chronic otitis media. Otolaryngol Head Neck Surg 2003;128: 2731.
  • 17
    Tomonaga K, Chaen T, Kurono Y, Mogi G. Type I allergic reactions of the middle ear and eustachian tube: an experimental study. Auris Nasus Larynx 1990;17: 121131.
  • 18
    Johansson SG, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF et al. Revised nomenclature for allergy for global use: report of the nomenclature review committee of the world allergy organization, October 2003. J Allergy Clin Immunol 2004;113: 832836.
  • 19
    Bachert C, Van Cauwenberge P. The Who Aria (allergic rhinitis and its impact on asthma) initiative. Chem Immunol Allergy 2003;82: 119126.
  • 20
    Williams HC, Burney PG, Hay RJ, Archer CB, Shipley MJ, Hunter JJ et al. The U.K. working party's diagnostic criteria for atopic dermatitis. I. derivation of a minimum set of discriminators for atopic dermatitis. Br J Dermatol 1994;131: 383396.
  • 21
    Ortolani C, Bruijnzeel-Koomen C, Bengtsson U, Bindslev-Jensen C, Bjorksten B, Host A et al. Controversial aspects of adverse reactions to food. European Academy of Allergology and Clinical Immunology (EAACI) Reactions to Food Subcommittee. Allergy 1999;54: 2745.
  • 22
    Demoly P, Bousquet J. Drug allergy diagnosis work up. Allergy 2002; 57(Suppl. 72):3740.
  • 23
    Daly KA, Hunter LL, Giebink GS. Chronic otitis media with effusion. Pediatr Rev 1999;20: 8593.
  • 24
    Van Cauwenberge PB, Bellussi L, Maw AR, Paradise JL, Solow B. The adenoid as a key factor in upper airway infections. Int J Pediatr Otorhinolaryngol 1995;32(Suppl.):S71S80.
  • 25
    Aydogan B, Kiroglu M, Altintas D, Yilmaz M, Yorgancilar E, Tuncer U. The role of food allergy in otitis media with effusion. Otolaryngol Head Neck Surg 2004;130: 747750.
  • 26
    Irander K, Borres MP, Bjorksten B. Middle ear diseases in relation to atopy and nasal metachromatic cells in infancy. Int J Pediatr Otorhinolaryngol 1993;26: 19.
  • 27
    Bernstein JM, Lee J, Conboy K, Ellis E, LI P. The role of IgE mediated hypersensitivity in recurrent otitis media with effusion. Am J Otol 1983;5: 6669.
  • 28
    Fokkens WJ, Vinke JG, De Jong SS, Bogaert DP, Kleinjan A, Eichhorn E. Differences in cellular infiltrates in the adenoid of allergic children compared with age- and gender-matched controls. Clin Exp Allergy 1998;28: 187195.
  • 29
    Papadopoulos NGPS, Manoussakis E, Saxoni-Papageorgiou P. The role of respiratory viruses in the origin and exacerbations of asthma. Curr Opin Allergy Clin Immunol 2003;3: 3944.
  • 30
    Labadie RF, Jewett BS, Hart CF, Prazma J, Pillsbury HC III. Allergy increases susceptibility to otitis media with effusion in a rat model. Second place–resident clinical science award 1998. Otolaryngol Head Neck Surg 1999;121: 687692.
  • 31
    Holgate ST. Asthma and allergydisorders of civilization? QJM 1998;91: 171184.
  • 32
    Papadopoulos NG, Stanciu LA, Papi A, Holgate ST, Johnston SL. A defective type 1 response to rhinovirus in atopic asthma. Thorax 2002;57: 328332.
  • 33
    Ogra PL. Mucosal immune response in the ear, nose and throat. Pediatr Infect Dis J 2000;19(Suppl. 5):S4S8.
  • 34
    Daly KA, Rich SS, Levine S, Margolis RH, Le CT, Lindgren B et al. The family study of otitis media: design and disease and risk factor profiles. Genet Epidemiol 1996;13: 451468.
  • 35
    Casselbrant ML, Redfern MS, Furman JM, Fall PA, Mandel EM. Visualinduced postural sway in children with and without otitis media. Ann Otol Rhinol Laryngol 1998;107: 401405.