• 1
    Kinet JP. The high-affinity IgE receptor (Fc epsilon RI): from physiology to pathology. Annu Rev Immunol 1999;17: 931972.
  • 2
    Bodtger U, Poulsen LK, Malling HJ. Asymptomatic skin sensitization to birch predicts later development of birch pollen allergy in adults: a 3-year follow-up study. J Allergy Clin Immunol 2003;111: 149154.
  • 3
    Bodtger U. Prognostic value of asymptomatic skin sensitization to aeroallergens. Curr Opin Allergy Clin Immunol 2004;4: 510.
  • 4
    Galli SJ. Mast cells and basophils. Curr Opin Hematol 2000;7: 3239.
  • 5
    Prussin C, Metcalfe DD. 4. IgE, mast cells, basophils, and eosinophils. J Allergy Clin Immunol 2003;111(Suppl. 2):S486S494.
  • 6
    Lowman MA, Rees PH, Benyon RC, Church MK. Human mast cell heterogeneity: histamine release from mast cells dispersed from skin, lung, adenoids, tonsils, and colon in response to IgE-dependent and nonimmunologic stimuli. J Allergy Clin Immunol 1988;81: 590597.
  • 7
    Peng Q, McEuen AR, Benyon RC, Walls AF. The heterogeneity of mast cell tryptase from human lung and skin. Eur J Biochem 2003;270: 270283.
  • 8
    Conroy MC, Adkinson NF Jr, Lichtenstein LM. Measurement of IgE on human basophils: relation to serum IgE and anti-IgE-induced histamine release. J Immunol 1977;118: 13171321.
  • 9
    Malveaux FJ, Conroy MC, Adkinson NF Jr, Lichtenstein LM. IgE receptors on human basophils, relationship to serum IgE concentration. J Clin Invest 1978;62: 176181.
  • 10
    MacGlashan D Jr, Xia HZ, Schwartz LB, Gong J. IgE-regulated loss, not IgE-regulated synthesis, controls expression of FcepsilonRI in human basophils. J Leukoc Biol 2001;70: 207218.
  • 11
    Kubo S, Matsuoka K, Taya C, Kitamura F, Takai T, Yonekawa H et al. Drastic up-regulation of Fcepsilonri on mast cells is induced by IgE binding through stabilization and accumulation of Fcepsilonri on the cell surface. J Immunol 2001;167: 34273434.
  • 12
    Borkowski TA, Jouvin MH, Lin SY, Kinet JP. Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI. J Immunol 2001;167: 12901296.
  • 13
    Jensen BM, Hansen JB, Dissing S, Gerwien J, Skov PS, Poulsen LK. Monomeric immunoglobulin E stabilizes FcepsilonRIalpha from the human basophil cell line KU812 by protecting it from natural turnover. Clin Exp Allergy 2003;33: 655662.
  • 14
    Novak N, Kraft S, Bieber T. IgE receptors. Curr Opin Immunol 2001;13: 721726.
  • 15
    Donnadieu E, Jouvin MH, Kinet JP. A second amplifier function for the allergy-associated Fc (epsilon)RI-beta subunit. Immunity 2000;12: 515523.
  • 16
    Lin S, Cicala C, Scharenberg AM, Kinet JP. The Fc (epsilon)RIbeta subunit functions as an amplifier of Fc (epsilon)RIgamma-mediated cell activation signals. Cell 1996;85: 985995.
  • 17
    Donnadieu E, Jouvin MH, Rana S, Moffatt MF, Mockford EH, Cookson WO et al. Competing functions encoded in the allergy-associated F (c)epsilonRIbeta gene. Immunity 2003;8: 665674.
  • 18
    Jensen BM, Dissing S, Skov PS, Poulsen LK. A comparative study of the FcepsilonRI molecule on human mast cell and basophil cell lines. Int Arch Allergy Immunol 2005;137: 93103.
  • 19
    Fiebiger E, Tortorella D, Jouvin MH, Kinet JP, Ploegh HL. Cotranslational endoplasmic reticulum assembly of FcvarepsilonRI controls the formation of functional IgE-binding receptors. J Exp Med 2005;201: 267277.
  • 20
    Dreborg S, Frew A. Allergen standardization and skin test. Allergy (Suppl.) 1993;48: 4962.
  • 21
    Poulsen LK, Weeke B. Aluminium hydroxide adsorbed allergens used in modified RAST. Allergy 1985;40: 405416.
  • 22
    Skov PS, Mosbech H, Norn S, Weeke B. Sensitive glass microfibre-based histamine analysis for allergy testing in washed blood cells. Results compared with conventional leukocyte histamine release assay. Allergy 1985;40: 213221.
  • 23
    Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227: 680685.
  • 24
    Saini SS, Richardson JJ, Wofsy C, Lavens-Phillips S, Bochner BS, Macglashan DW Jr. Expression and modulation of FcepsilonRIalpha and FcepsilonRIbeta in human blood basophils. J Allergy Clin Immunol 2001;107: 832841.
  • 25
    Ohashi Y, Nakai Y, Tanaka A, Kakinoki Y, Masamoto T, Kato A et al. Allergen-induced synthesis of interleukin-5, but not of IgE, is a key mechanism linked to symptomatic episodes of seasonal allergic rhinitis in sensitized individuals. Scand J Immunol 1998;47: 596602.
  • 26
    Tanizaki Y, Komagoe H, Sudo M, Morinaga H, Kitani H, Kimura I. Comparison of basophil histamine release induced by the cross-linking of IgE receptors. Acta Med Okayama 1985;39: 441446.
  • 27
    Marone G, Spadaro G, Patella V, Genovese A. The clinical relevance of basophil releasability. J Allergy Clin Immunol 1994;94(6 Pt 2):12931303.
  • 28
    MacGlashan D Jr, Lichtenstein LM, McKenzie-White J, Chichester K, Henry AJ, Sutton BJ et al. Upregulation of FcepsilonRI on human basophils by IgE antibody is mediated by interaction of IgE with FcepsilonRI. J Allergy Clin Immunol 1999;104(2 Pt 1):492498.
  • 29
    Nguyen KL, Gillis S, Macglashan Jr DW. A comparative study of releasing and nonreleasing human basophils: nonreleasing basophils lack an early component of the signal transduction pathway that follows IgE cross-linking. J Allergy Clin Immunol 1990;85: 10201029.
  • 30
    Kuster H, von Manstein S, Ruocchio-Wiglinghaus S, von Brunn A, Reinhardt D. Mutations in the high-affinity IgE receptor beta-chain are not associated with nonresponder status. Allergy 2005;60: 10401045.
  • 31
    Kepley CL, Youssef L, Andrews RP, Wilson BS, Oliver JM. Syk deficiency in nonreleaser basophils. J Allergy Clin Immunol 1999;104(2 Pt 1):279284.
  • 32
    Kepley CL, Youssef L, Andrews RP, Wilson BS, Oliver JM. Multiple defects in Fc epsilon RI signaling in Syk-deficient nonreleaser basophils and IL-3-induced recovery of Syk expression and secretion. J Immunol 2000;165: 59135920.
  • 33
    Parravicini V, Gadina M, Kovarova M, Odom S, Gonzalez-Espinosa C, Furumoto Y et al. Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation. Nat Immunol 2002;3: 741748.
  • 34
    Yamaguchi M, Hirai K, Ohta K, Suzuki K, Kitani S, Takaishi T et al. Nonreleasing basophils convert to releasing basophils by culturing with IL-3. J Allergy Clin Immunol 1996;97: 12791287.