• 1
    Stewart CNJ, Adang MJ, All JN, Boerma HR, Cardineau G, Tucker D et al. Genetic transformation, recovery, and characterization of fertile soybean transgenic for a synthetic Bacillus thuringiensis cryIAc gene. Plant Physiol 1996;112: 121129.
  • 2
    Padgette SR, Kolacz KH, Delannay X, Re DB, LaVallee BJ, Tinius CN et al. Development, identification, and characterization of a glyphosate-tolerant soybean line. Crop Sci 1995;35: 14511461.
  • 3
    Song JD, Lee MH, Chang HS, Lee CH. Quick screening of phosphinothricin-resistant transgenic tobacco plants using chlorophyll fluorescence. Mol Cells 1996;6: 405410.
  • 4
    Yeo ET, Kwon HB, Han SE, Lee JT, Ryu JC, Byun MO. Genetic engineering of drought resistant potato plants by introduction of the trehalose-6 phosphate synthase (tsp1) gene from Saccharomyces cerevisiae. Mol Cells 2000;11: 263268.
  • 5
    Jeong MJ, Park SC, Byun MO. Improvement of salt tolerance in transgenic plants by glyceraldehyde-3 phosphate dehydrogenase gene transfer. Mol Cells 2001;12: 185189.
  • 6
    Datta K, Baisakh N, Oliva N, Torrizo L, Abrigo E, Tan J et al. Bioengineered ‘golden’ indica rice cultivars with â-carotene metabolism in the endosperm with hygromycin and mannose selection systems. Plant Biotechnol J 2003;1: 8190.
  • 7
    Tacket CO. Plant-derived vaccines against diarrheal diseases. Vaccine 2005;23: 18661869.
  • 8
    Evaluation of Allergenicity of Genetically Modified Foods. Report of a Joint FAO/WHO Expert Consultation on Allergenicity of Foods Derived from Biotechnology, 22–25 January 2001. Rome: Food and Agriculture Organisation of the United Nations, 2001. http://www. [accessed on 6 June 2005].
  • 9
    Organization for Economic cooperation and Development. Report of the OECD Workshop on the Toxicological and Nutritional Testing of Novel Foods, Aussois, France, 5–8 March 1997. France: Organization for Economic cooperation and Development, 1998. http://www.olis.oecd.rg/oils/1998doc.nsf/LinkTo/sg-icgb (98) 1-final [accessed on 6 June 2005].
  • 10
    Lehrer SB, Bannon GA. Risks of allergic reactions to biotech proteins in foods: perception and reality. Allergy 2005;60: 559564.
  • 11
    Sampson HA. Update on food allergy. J Allergy Clin Immunol 2004;113: 805819.
  • 12
    Burks AW, Fuchs RL. Assessment of the endogenous allergens in glyphosate-tolerant and commercial soybean varieties. J Allergy Clin Immunol 1995;96: 10081010.
  • 13
    Gavrovic-Jankulovic M, Cirkovic T, Burazer L, Vuckovic O, Jankov RM. IgE cross-reactivity between meadow fescue pollen and kiwi fruit in patients’ sera with sensitivity to both extracts. J Investig Allergol Clin Immunol 2002;12: 279286.
  • 14
    Nordlee JA, Taylor SL, Townsend JA, Thomas LA, Bush RK. Identification of a Brazil-nut allergen in transgenic soybeans. New Engl J Med 1996;334: 688692.
  • 15
    Bucchini L, Goldman LR. Starlink corn: a risk analysis. Environ Health Perspect 2002;110: 513.
  • 16
    Astwood JD, Leach JN, Fuchs RL. Stability of food allergens to digestion in vitro. Nat Biotechnol 1996;14: 12691273.
  • 17
    Wayne W, Teni B, Virginia PW, Ronald H, Silver staining of proteins in polyacrylamide gels. Anal Biochem 1981;118: 197203.
  • 18
    Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979;76: 43504354.
  • 19
    Prasad KVSK, Sharmila P, Pardha Saradhi P. Enhanced tolerance of transgenic Brassica juncea to choline confirms successful expression of the bacterial codA gene. Plant Sci 2000;159: 233242.
  • 20
    American Thoracic Society. Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 1991;144: 12021218.
  • 21
    Adomopoulos G, Monolopoulos L, Giotakis I. A comparison of the efficacy and the patient's acceptability of budesonide and beclomethanosone dipropionate aqueous nasal sprays in patients with perennial rhinitis. Clin Otolarnygol 1995;20: 340344.
  • 22
    Aggarwal S, Chhabra SK, Saxena RK, Agarwal MK. Heterogeneity of immune responses to various Aspergillus species in patients with allergic respiratory diseases. Indian J Chest Dis Allied Sci 2000;42: 249258.
  • 23
    Voller A, Bidwel DE, Barlett A. Enzyme-linked immunosorbent assay. Manual of clinical immunology. Washington: American Society of Microbiology, 1980.
  • 24
    Li XM, Serebrisky D, Lee SY, Huang CK, Bardina L, Schofield BH et al. A murine model of peanut anaphylaxis: T- and B-cell responses to a major peanut allergen mimic human responses. J Allergy Clin Immunol 2000;106: 150158.
  • 25
    Shen HD, Choo KB, Yu KW, Ling WL, Chang FC, Han SH. Characterization of a monoclonal antibody (RJ5) against the immunodominant 41-kD antigen of Candida albicans. Int Arch Allergy Appl Immunol 1991;96: 142148.
  • 26
    Beardslee TA, Zeece MG, Sarath G, Markwell JP. Soybean glycinin G1 acidic chain shares IgE epitopes with peanut allergen Ara h 3. Int Arch Allergy Immunol 2000;123: 299307.
  • 27
    Kuiper HA, Kleter GA, Noteborn HPJM, Kok EJ. Assessment of the food safety issues related to genetically modified foods. Plant J 2001;27: 503528.
  • 28
    Sakamoto A, Alia, Murata N. Metabolic engineering of rice leading to biosynthesis of glycinebetaine and tolerance to salt and cold. Plant Mol Biol 1998;38: 10111019.
  • 29
    Parvanova D, Ivanov S, Konstantinova T, Karanov E, Atanassov A, Tsvetkov T et al. Transgenic tobacco plants accumulating osmolytes show reduced oxidative damage under freezing stress. Plant Physiol Biochem 2004;42: 5763.
  • 30
    Park EJ, Jeknic Z, Sakamoto A, DeNoma J, Yuwansiri R, Murata N et al. Genetic engineering of glycinebetaine synthesis in tomato protects seeds, plants, and flowers from chilling damage. Plant J 2004;40: 474487.
  • 31
    Sakamoto A, Valverde R, Alia, Chen TH, Murata N. Transformation of Arabidopsis with the codA gene for choline oxidase enhances freezing tolerance of plants. Plant J 2000;22: 449453.
  • 32
    Karisola P, Mikkola J, Kalkkinen N, Airenne KJ, Laitinen OH, Repo S et al. Construction of Hevein (Hev b 6.02) with reduced allergenicity for immunotherapy of latex allergy by commutation of six amino acid residues on the conformational IgE epitopes. J Immunol 2004;172: 26212628.
  • 33
    Hileman RE, Silvanovich A, Goodman RE, Rice EA, Holleschak G, Astwood JD et al. Bioinformatic methods for allergenicity assessment using a comprehensive allergen database. Int Arch Allergy Immunol 2002;128: 280291.
  • 34
    Batista R, Nunes B, Carmo M, Cardoso C, Jose HS, de Almeida AB et al. Lack of detectable allergenicity of transgenic maize and soya samples. J Allergy Clin Immunol 2005;116: 403410.
  • 35
    Dearman R, Kimber I. Determination of protein allergenicity: studies in mice. Toxicol Lett 2001;120: 181186.
  • 36
    Knippels LM, Houben GF, Spanhaak S, Penninks AH. An oral sensitization model in Brown Norway rats to screen for potential allergenicity of food proteins. Methods 1999;19: 7882.
  • 37
    Holt PG, Macaubas C, Stumbles PA, Sly PD. The role of allergy in the development of asthma. Nature 1999;402: B12.