• 1
    Masoli M, Fabian D, Holt S, Beasley R. Global Initiative for Asthma (GINA) program. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004;59:469478.
  • 2
    Braman S. The global burden of asthma. Chest 1006;130(1 Suppl.):S4S12.
  • 3
    Pawankar R. Allergic rhinitis and asthma: the link, the new ARIA classifications and global approaches to treatment. Curr Opin Allergy Clin Immunol 2004;4:14.
  • 4
    Bousquet J, Van Cauwenberge P, Khaltaev N, ARIA Workshop Group, World Health Organization. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 2001;108(5 Suppl.):S147S334.
  • 5
    Leynaert B, Neukirch F, Demoly P, Bousquet J. Epidemiologic evidence for asthma and rhinitis comorbidity. J Allergy Clin Immunol 2000;106(5 Suppl.):S201S205.
  • 6
    Price D, Zhang Q, Kocevar VS, Yin DD, Thomas M. Effect of a concomitant diagnosis of allergic rhinitis on asthma-related health care use by adults. Clin Exp Allergy 2005;35:282287.
  • 7
    Braunstahl GJ, Fokkens W. Nasal involvement in allergic asthma. Allergy 2003;58:12351243.
  • 8
    Valovirta E, Pawankar R. Survey on the impact of comorbid allergic rhinitis in patients with asthma. BMC Pulm Med 2006;6(1 Suppl.):S3. doi: DOI: 10.1186/1471-2466-6-S1-S3.
  • 9
    Van Den Boom G, Rutten-van Mölken MPMH, Tirimanna PRS, Van Schayck CP, Folgering H, Van Weel C. Association between health-related quality of life and consultation for respiratory symptoms: results from the DIMCA program. Eur Respir J 1998;11:6772.
  • 10
    Van Weel C. Underdiagnosis of asthma and COPD: is the general practitioner to blame? Monaldi Arch Chest Dis 2002;57:6568.
  • 11
    Global Tuberculosis Control: Surveillance, Planning, Financing. World Health Organization Report 2004. Switzerland, Geneva: World Health Organization.
  • 12
    Mash B, Whittaker D. An audit of asthma care at Khayelitsha Community Health Centre. S Afr Med J 1997;87:475476.
  • 13
    Boulet LP, Phillips R, O'Byrne P, Becker A. Evaluation of asthma control by physicians and patients’ comparison with current guidelines. Can Respir J 2002;9:377378.
  • 14
    Watson JP, Lewis RA. Is asthma treatment affordable in developing countries? Thorax 1997;52:605607.
  • 15
    Masoli M, Fabian D, Holt S, Beasley R for the Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA dissemination committee report. Allergy 2004;59:469478.
  • 16
    Grimshaw J, Russell I. Effect of clinical guideline on medical practice: a systematic review of rigorous evaluations. Lancet 1993;342:13171322.
  • 17
    Effective Health Care Bulletin. Implementing clinical practice guidelines. York: University of York, 1994.
  • 18
    IMCI. Integrated Management of Childhood Illnesses [homepage on the Internet]. Available from:
  • 19
    Behets FM, Williams Y, Brathwaite A, Hylton-Kong T, Hoffman IF, et al. Management of vaginal discharge in women treated at a Jamaican sexually transmitted disease clinic: use of diagnostic algorithms versus laboratory testing. Clin Infect Dis 1995;21:14501455.
  • 20
    The Practical Approach to Lung Health [homepage on the Internet]. Available from:
  • 21
    World Health Organization. Practical Approach to Lung Health (PAL). A primary health care strategy for integrated management of priority respiratory illnesses. Geneva: World Health Organization, 2003.
  • 22
    Levy ML, Fletcher M, Price DB, Hausen T, Albert RJ, Yawn BP. International Primary Care Respiratory Group (IPCRG) Guidelines: diagnosis of respiratory diseases in primary care. Prim Care Respir J 2006;15:2034.
  • 23
    General Practice Airways Group Allergy UK. The 6-point asthma and allergic rhinitis status measure [Available from:].
  • 24
    World Health Organization and Stop TB Partnership. The Stop TB strategy. Building on and enhancing DOTS to meet the TB-related Millennium Development Goals. Geneva: World Health Organization, 2006 (WHO/HTM/STB/2006.37).
  • 25
    English RG, Bachmann MO, Bateman ED, Zwarenstein MF, Fairall LR, Bheekie A et al. Diagnostic accuracy of an integrated respiratory guideline in identifying patients with respiratory symptoms requiring screening for pulmonary tuberculosis: a cross-sectional study. BMC Pulm Med 2006;6:22. doi:10.1186/1471-2466-6-22.
  • 26
    Fairall LR, Zwarenstein M, Bateman ED, Bachmann M, Lombard C, Majara BP et al. Effect of education outreach to nurses on tuberculosis case detection and primary care of respiratory illness: pragmatic cluster randomised controlled trial. BMJ 2005;331:750754.
  • 27
    Bheekie A, Buskens I, Allen S, English R, Mayers P, Fairall L et al. The Practical Approach to Lung Health (PALSA) intervention: respiratory guideline implementation for nurse trainers. Int Nurs Rev 2006;53:261268.
  • 28
    Enright P. Does screening for COPD by primary care physicians have the potential to cause more harm than good. Chest 2006;129:833835.
  • 29
    Lusuardi M, DeBenedetto F, Paggiaro P, Sanguinetti CM, Brazzola G, Ferri P et al. A randomized controlled trial on office spirometry in asthma and COPD in standard general practice. Chest 2006;129:844852
  • 30
    South African National Department of Health. Standard Treatment Guidelines and Essential Drugs List for South Africa, 2nd edn. Pretoria, South Africa: South African National Department of Health, 1998.
  • 31
    SIGN (Scottish Intercollegiate Guidelines Network) [homepage on the Internet]. Available from:
  • 32
    NICE (National Institute for Clinical Excellence) [homepage on the Internet]. Available from:
  • 33
    NZGG (New Zealand Guidelines Group) [homepage on the Internet]. Available from:
  • 34
    Grol R. Personal paper: Beliefs and evidence in changing clinical practice. BMJ 1997;315:418421.
  • 35
    Grimshaw JM, Shirran L, Thomas R, Mowatt G, Fraser C, Bero L et al. Changing provider behavior: an overview of systematic reviews of interventions. Med Care 2001;39:II2II45.
  • 36
    GINA: The Global Initiative for Asthma [].
  • 37
    Global strategy for the diagnosis, management, and prevention of COPD. Executive summary. Available from:
  • 38
    Ai̇t-Khaled N, Enarson D. Management of asthma in adults: a guide for low-income countries. Paris: IUATLD, 1996.
  • 39
    Global Initiative for Asthma Report. Global Strategy for asthma management and prevention. Available from:
  • 40
    Bero L, Grilli R, Grimshaw JM, Mowatt G, Oxman A, Zwarenstein M. Cochrane Effective Practice and Organisation of Care Review Group (Cochrane Group Module). In: BeroL, GrilliR, GrimshawJM, MowattG, OxmanA, ZwarensteinM, editors. The Cochrane Library (Issue 3) 2001. Oxford: Update Software.
  • 41
    Mesters I, Meertens R, Kok G, Parcel GS. Effectiveness of a multidisciplinary education protocol in children with asthma (0–4 years) in primary health care. J Asthma 1994;31:347359.
  • 42
    Bryce FP, Neville RG, Crombie IK, Clark RA, McKenzie P. Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice. BMJ 1995;310:838842.
  • 43
    Feder G, Griffiths C, Highton C, Eldridge S, Spence M, Southgate L. Do clinical guidelines introduced with practice based education improve care of asthmatic and diabetic patients? A randomised controlled trial in general practices in east London. BMJ 1995;311:14731478.
  • 44
    Zwarenstein M, Adams J, Bheekie A, Swingler G, Ehrlich R, Lombard C et al. Chestiness and asthma in Mitchell's Plain (CHAMP): Cluster randomised controlled trial of academic outreach demonstrates improved health status of asthmatic children attending private practitioners in poor urban community in South Africa. 30th International Union Against Tuberculosis and Lung Disease (IUATLD) World Conference on Lung Health, Madrid, Spain, September 1999.
  • 45
    Thomson MA, Oxman AD, Davis DA et al. 1999. Outreach visits to improve health professional practice and health care outcomes (Cochrane Review). In: The Cochrane Library, Issue 1. Oxford: Update software.
  • 46
    Grimshaw JM, Thomas RE, MacLennan G, Fraser C, Ramsay C, Vale L et al. Effectiveness and efficiency of guideline dissemination and implementation strategies. Health Technol Assess, 2004;8:iiiiv, 1–72.
  • 47
    Raviglione M. The TB epidemic from 1992 to 2002. Tuberculosis 2003;83:414.
  • 48
    Victora CG, Hanson K, Bryce J, Vaughan JP. Achieving universal coverage with health interventions. Lancet 2004;364:15411548.
  • 49
    Task Force on Health Systems Research. Informed choices for attaining the Millennium Development Goals: towards an international cooperative agenda for health systems research. Lancet 2004;364:9971003.
  • 50
    Stein J, Lewin S, Fairall LR. ‘Hope is the pillar of the universe’: health care providers’ experiences of delivering anti-retroviral therapy in primary health care clinics in South Africa. Soc Sci Med 2007;64:954964.