• 1
    Beyer K, Grishina G, Bardina L, Grishin A, Sampson HA. Identification of an 11S globulin as a major hazelnut food allergen in hazelnut-induced systemic reactions. J Allergy Clin Immunol 2002;110:517523.
  • 2
    Ortolani C, Ballmer-Weber BK, Skamstrup Hansen K, Ispano M, Wüthrich B, Bindslev-Jensen C et al. Hazelnut allergy: a double-blind, placebo-controlled food challenge multicenter study. J Allergy Clin Immunol 2000;105:577581.
  • 3
    Roux KH, Teuber SS, Sathe SK. Tree nut allergens. Int Arch Allergy Immunol 2003;131:234244.
  • 4
    Hirschwehr R, Valenta R, Ebner C, Ferreira F, Sperr WR, Valent P et al. Identification of common allergenic structures in hazel pollen and hazelnuts: a possible explanation for sensitivity to hazelnuts in patients allergic to tree pollen. J Allergy Clin Immunol 1992;90:927936.
  • 5
    Lüttkopf D, Müller U, Skov PS, Ballmer-Weber BK, Wüthrich B, Skamstrup Hansen K et al. Comparison of four variants of a major allergen in hazelnut (Corylus avellana) Cor a 1.04 with the major hazel pollen allergen Cor a 1.01. Mol Immunol 2001;38:515525.
  • 6
    Müller U, Lüttkopf D, Hoffmann A, Petersen A, Becker WM, Schocker F et al. Allergens in raw and roasted hazelnuts (Corylus avellana) and their cross-reactivity to pollen. Eur Food Res Technol 2000;212:212.
  • 7
    Pastorello EA, Vieths S, Pravettoni V, Farioli L, Trambaioli C, Fortunato D et al. Identification of hazelnut major allergens in sensitive patients with positive double-blind, placebo-controlled food challenge results. J Allergy Clin Immunol 2002;109:563570.
  • 8
    Schocker F, Lüttkopf D, Müller U, Thomas P, Vieths S, Becker W-M. IgE binding to unique hazelnut allergens: identification of non pollen-related and heat-stable hazelnut allergens eliciting severe allergic reactions. Eur J Nutr 2000;39:172180.
  • 9
    Skamstrup Hansen K, Ballmer-Weber BK, Lüttkopf D, Skov PS, Wüthrich B, Bindslev-Jensen C et al. Roasted hazelnuts – allergenic activity evaluated by double-blind, placebo-controlled food challenge. Allergy 2003;58:132138.
  • 10
    Wensing M, Akkerdaas JH, Van Leeuwen A, Stapel SO, Bruijnzeel-Koomen C, Aalberse RC et al. IgE to Bet v 1 and profilin: cross-reactivity patterns and clinical relevance. J Allergy Clin Immunol 2002;110:435442.
  • 11
    Lauer I, Foetisch K, Kolarich D, Ballmer-Weber BK, Conti A, Altmann F et al. Hazelnut (Corylus avellana) vicilin Cor a 11: molecular characterization of a glycoprotein and its allergenic activity. Biochem J 2004;383:327334.
  • 12
    Akkerdaas JH, Schocker F, Vieths S, Versteeg S, Zuidmeer L, Hefle SL et al. Cloning of oleosin, a putative new hazelnut allergen, using a hazelnut cDNA library. Mol Nutr Food Res 2006;50:1823.
  • 13
    Wensing M, Koppelman SJ, Penninks AH, Bruijnzeel-Koomen CA, Knulst AC. Hidden hazelnut is a threat to allergic patients. Allergy 2001;56:191192.
  • 14
    Roehr CC, Edenharter G, Reimann S, Ehlers I, Worm M, Zuberbier T et al. Food allergy and non-allergic food hypersensitivity in children and adolescents. Clin Exp Allergy 2004;34:15341541.
  • 15
    Eriksson NE, Möller C, Werner S, Magnusson J, Bengtsson U, Zolubas M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig Allergol Clin Immunol 2004;14:7079.
  • 16
    De Groot H, De Jong NW, Vuijk MH, Gerth van Wijk R. Birch pollinosis and atopy caused by apple, peach, and hazelnut; comparison of three extraction procedures with two apple strains. Allergy 1996;51:712718.
  • 17
    Asero R, Mistrello G, Roncarolo D, Amato S, Caldironi G, Barocci F et al. Immunological cross-reactivity between lipid transfer proteins from botanically unrelated plant-derived foods: a clinical study. Allergy 2002;57:900906.
  • 18
    Schocker F, Lüttkopf D, Scheurer S, Petersen A, Cistero-Bahima A, Enrique E et al. Recombinant lipid transfer protein Cor a 8 from hazelnut: a new tool for in vitro diagnosis of potentially severe hazelnut allergy. J Allergy Clin Immunol 2004;113:141147.
  • 19
    Akkerdaas JH, Wensing M, Knulst AC, Aalberse RC, Hefle SL, Van Ree R. In vitro and in vivo characterization of hazelnut skin prick test extracts. Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M 2003;95:96.
  • 20
    Akkerdaas JH, Wensing M, Knulst AC, Krebitz M, Breiteneder H, De Vries S et al. How accurate and safe is the diagnosis of hazelnut allergy by means of commercial skin prick test reagents? Int Arch Allergy Immunol 2003;132:132140.
  • 21
    Ballmer-Weber BK, Scheurer S, Fritsche P, Enrique E, Cistero-Bahima A, Haase T et al. Component-resolved diagnosis with recombinant allergens in patients with cherry allergy. J Allergy Clin Immunol 2002;110:167173.
  • 22
    Kleine-Tebbe J, Wangorsch A, Vogel L, Crowell DN, Haustein UF, Vieths S. Severe oral allergy syndrome and anaphylactic reactions caused by a Bet v 1-related PR-10 protein in soybean, SAM22. J Allergy Clin Immunol 2002;110:797804.
  • 23
    Mittag D, Akkerdaas J, Ballmer-Weber BK, Vogel L, Wensing M, Becker WM et al. Ara h 8, a Bet v 1-homologous allergen from peanut, is a major allergen in patients with combined birch pollen and peanut allergy. J Allergy Clin Immunol 2004;114:14101417.
  • 24
    Mittag D, Vieths S, Vogel L, Becker WM, Rihs HP, Helbling A et al. Soybean allergy in patients allergic to birch pollen: clinical investigation and molecular characterization of allergens. J Allergy Clin Immunol 2004;113:148154.
  • 25
    Vieths S, Scheurer S, Reindl J, Lüttkopf D, Wangorsch A, Kastner M et al. Optimized allergen extracts and recombinant allergens in diagnostic applications. Allergy 2001;56:7882.
  • 26
    Clark AT, Ewan PW. Interpretation of tests for nut allergy in one thousand patients, in relation to allergy or tolerance. Clin Exp Allergy 2003;33:10411045.
  • 27
    Ortolani C, Ispano M, Pastorello E, Ansaloni R, Magri G. Comparison of results of skin prick tests (with fresh foods and commercial food extracts) and RAST in 100 patients with oral allergy syndrome. J Allergy Clin Immunol 1989;83:683690.
  • 28
    Wensing M, Penninks AH, Hefle SL, Akkerdaas JH, Van Ree R, Koppelman SJ et al. The range of minimum provoking doses in hazelnut-allergic patients as determined by double-blind, placebo-controlled food challenges. Clin Exp Allergy 2002;32:17571762.
  • 29
    Marknell DeWitt Å, Niederberger V, Lehtonen P, Spitzauer S, Sperr WR, Valent P et al. Molecular and immunological characterization of a novel timothy grass (Phleum pratense) pollen allergen, Phl p 11. Clin Exp Allergy 2002;32:13291340.
  • 30
    Hsieh L, Moos MJ, Lin Y. Characterization of apple 18 and 31 kD allergens by microsequencing and evaluation of their content during storage and ripening. J Allergy Clin Immunol 1995;96:960970.
  • 31
    Vieths S, Jankiewicz A, Schöning B, Aulepp H. Apple allergy: the IgE-binding potency of apple strains is related to the occurrence of the 18-kDa allergen. Allergy 1994;49:262271.
  • 32
    Björksten F, Halmepuro L, Hannuksela M, Lahti A. Extraction and properties of apple allergens. Allergy 1980;35:671677.
  • 33
    Rudeschko O, Fahlbusch B, Henzgen M, Schlenvoigt G, Herrmann D, Vieths S et al. Investigation of the stability of apple allergen extracts. Allergy 1995;50:575580.
  • 34
    Vieths S, Hoffmann A, Holzhauser T, Müller U, Reindl J, Haustein D. Factors influencing the quality of food extracts for in vitro and in vivo diagnosis. Allergy 1998;53:6571.
  • 35
    Sampson HA. Food allergy – accurately identifying clinical reactivity. Allergy 2005;60(Suppl. 79):1924.