Administration regimens for sublingual immunotherapy to pollen allergens: What do we know?
Version of Record online: 14 APR 2009
© 2009 John Wiley & Sons A/S
Volume 64, Issue 6, pages 849–854, June 2009
How to Cite
Lombardi, C., Incorvaia, C., Braga, M., Senna, G., Canonica, G. W. and Passalacqua, G. (2009), Administration regimens for sublingual immunotherapy to pollen allergens: What do we know?. Allergy, 64: 849–854. doi: 10.1111/j.1398-9995.2009.02063.x
- Issue online: 11 MAY 2009
- Version of Record online: 14 APR 2009
- Accepted for publication 19 February 2009
- administration regimen;
- pollen allergen;
- sublingual immunotherapy
The modalities of administration of sublingual immunotherapy (SLIT), including dosing, build-up phase, duration of the treatment, and frequency of the maintenance dose are largely variable. In the case of pollen (SLIT), the complexity increases, since preseasonal, coseasonal and pre-coseasonal regimens can be used. The administration regimens are of relevance from a practical point of view, but can also have economic implications. We review herein the available literature (randomized double blind controlled studies) on pollen SLIT, in order to derive experimentally-supported suggestions about the regimens of administration that should be preferred.