Edited by: Wytske Fokkens
Impact of allergic rhinitis on asthma in children: effects on bronchodilation test
Article first published online: 1 OCT 2009
© 2009 John Wiley & Sons A/S
Volume 65, Issue 2, pages 264–268, February 2010
How to Cite
Capasso, M., Varricchio, A. and Ciprandi, G. (2010), Impact of allergic rhinitis on asthma in children: effects on bronchodilation test. Allergy, 65: 264–268. doi: 10.1111/j.1398-9995.2009.02168.x
- Issue published online: 5 JAN 2010
- Article first published online: 1 OCT 2009
- Accepted for publication 30 June 2009
- allergic rhinitis;
To cite this article: Capasso M, Varricchio A, Ciprandi G. Impact of allergic rhinitis on asthma in children: effects on bronchodilation test. Allergy 2010; 65: 264–268 DOI: 10.1111/j.1398-9995.2009.02168.x.
Background: Relevant relationship exists between upper and lower airways. Bronchial obstruction is a paramount feature of asthma and its reversibility is considered a diagnostic step for asthma diagnosis.
Objective: This study aimed at evaluating a large group of children with allergic rhinitis alone for investigating the degree of brochodilation and possible factors related to it.
Methods: Two hundred patients with allergic rhinitis and 150 normal subjects were consecutively evaluated. Clinical examination, skin prick test, spirometry, and bronchodilation test were performed in all patients.
Results: Rhinitics showed a significant FEV1 increase after bronchodilation test (P < 0.0001) in comparison both to basal values and to controls’ levels. More than 20% of rhinitics had reversibility (≥12% basal levels). Patients with reversibility had lower FEV1 levels, longer rhinitis duration, and perennial allergy.
Conclusion: This study highlights the close link between upper and lower airways and the relevance of performing bronchodilation test in patients with allergic rhinitis and these characteristics.