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Impact of allergic rhinitis on asthma in children: effects on bronchodilation test


  • Edited by: Wytske Fokkens

G. Ciprandi, Semeiotica e Metodologia Medica I, DIMI, A.O.U. San Martino, Viale Benedetto XV 6, 16132 Genoa, Italy.


To cite this article: Capasso M, Varricchio A, Ciprandi G. Impact of allergic rhinitis on asthma in children: effects on bronchodilation test. Allergy 2010; 65: 264–268 DOI: 10.1111/j.1398-9995.2009.02168.x.


Background:  Relevant relationship exists between upper and lower airways. Bronchial obstruction is a paramount feature of asthma and its reversibility is considered a diagnostic step for asthma diagnosis.

Objective:  This study aimed at evaluating a large group of children with allergic rhinitis alone for investigating the degree of brochodilation and possible factors related to it.

Methods:  Two hundred patients with allergic rhinitis and 150 normal subjects were consecutively evaluated. Clinical examination, skin prick test, spirometry, and bronchodilation test were performed in all patients.

Results:  Rhinitics showed a significant FEV1 increase after bronchodilation test (P < 0.0001) in comparison both to basal values and to controls’ levels. More than 20% of rhinitics had reversibility (≥12% basal levels). Patients with reversibility had lower FEV1 levels, longer rhinitis duration, and perennial allergy.

Conclusion:  This study highlights the close link between upper and lower airways and the relevance of performing bronchodilation test in patients with allergic rhinitis and these characteristics.