Methylprednisolone-induced anaphylaxis: diagnosis by skin test and basophil activation test

Authors


  • Although corticosteroids are used to treat allergic disorders, steroids themselves, however, can induce hypersensitivity reactions. We present the first case of intra-venous methylprednisolone anaphylactic reaction (MP) that occurred during anaesthesia, with positive skin tests and positive basophil activation test (BAT). Our case suggests that the BAT could be a sensitive in vitro assay for the diagnosis of MP or cortisteroids allergy.

*Université Lyon1
UFR Lyon-Sud, INSERM U851
Hospices Civils de Lyon, Service immunologie clinique et allergologie
Laboratoire d’Immunologie, Centre hospitalier Lyon-Sud
69495 Pierre Bénite
France
Tel.: 0478861572
Fax: 0478861526
E-mail: benoit.ben-said@chu-lyon.fr

No abstract is available for this article.

Ancillary