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Methylprednisolone-induced anaphylaxis: diagnosis by skin test and basophil activation test


  • Although corticosteroids are used to treat allergic disorders, steroids themselves, however, can induce hypersensitivity reactions. We present the first case of intra-venous methylprednisolone anaphylactic reaction (MP) that occurred during anaesthesia, with positive skin tests and positive basophil activation test (BAT). Our case suggests that the BAT could be a sensitive in vitro assay for the diagnosis of MP or cortisteroids allergy.

*Université Lyon1
UFR Lyon-Sud, INSERM U851
Hospices Civils de Lyon, Service immunologie clinique et allergologie
Laboratoire d’Immunologie, Centre hospitalier Lyon-Sud
69495 Pierre Bénite
Tel.: 0478861572
Fax: 0478861526

No abstract is available for this article.