• 1
    Bakker RA, Timmerman H, Leurs R. Histamine receptors: specific ligands, receptor biochemistry, and signal transduction. Clinical Allergy and Immunology 2002;17:2764.
  • 2
    Kobayashi T, Tonai S, Ishihara Y, Koga R, Okabe S, Watanabe T. Abnormal functional and morphological regulation of the gastric mucosa in histamine H2 receptor-deficient mice. The Journal of Clinical Investigation 2000;105:17411749.
  • 3
    Arrang JM, Garbarg M, Schwartz JC. Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor. Nature 1983;302:832837.
  • 4
    Nakamura T, Itadani H, Hidaka Y, Ohta M, Tanaka K. Molecular cloning and characterization of a new human histamine receptor, HH4R. Biochemical and Biophysical Research Communications 2000;279:615620.
  • 5
    Oda T, Morikawa N, Saito Y, Masuho Y, Matsumoto S. Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. The Journal of Biological Chemistry 2000;275:3678136786.
  • 6
    Hofstra CL, Desai PJ, Thurmond RL, Fung- Leung WP. Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells. The Journal of Pharmacology and Experimental Therapeutics 2003;305:12121221.
  • 7
    Gutzmer R, Diestel C, Mommert S, Kother B, Stark H, Wittmann M et al. Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. Journal of Immunology 2005;174:52245232.
  • 8
    Ling P, Ngo K, Nguyen S, Thurmond RL, Edwards JP, Karlsson L, Fung-Leung WP. Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation. British Journal of Pharmacology 2004;142:161171.
  • 9
    Dijkstra D, Leurs R, Chazot P, Shenton FC, Stark H, Werfel T et al. Histamine downregulates monocyte CCL2 production through the histamine H4 receptor. The Journal of Allergy and Clinical Immunology 2007;120:300307.
  • 10
    Dijkstra D, Stark H, Chazot PL, Shenton FC, Leurs R, Werfel T et al. Human inflammatory dendritic epidermal cells express a functional histamine H4 receptor. The Journal of Investigative Dermatology 2008;128:16961703.
  • 11
    Ohtani T, Aiba S, Mizuashi M, Mollah ZU, Nakagawa S, Tagami H. H1 and H2 histamine receptors are absent on Langerhans cells and present on dermal dendritic cells. The Journal of Investigative Dermatology 2003;121:10731079.
  • 12
    Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T. Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases. The Journal of Investigative Dermatology 2005;124:12251233.
  • 13
    Baumer W, Sulzle B, Weigt H, De Vries VC, Hecht M, Tschernig T et al. Cilomilast, tacrolimus and rapamycin modulate dendritic cell function in the elicitation phase of allergic contact dermatitis. The British Journal of Dermatology 2005;153:136144.
  • 14
    Jablonowski JA, Grice CA, Chai W, Dvorak CA, Venable JD, Kwok AK et al. The first potent and selective non-imidazole human histamine H4 receptor antagonists. Journal of Medicinal Chemistry 2003;46:39573960.
  • 15
    Baumer W, Wendorff S, Gutzmer R, Werfel T, Dijkstra D, Chazot P et al. Histamine H4 receptors modulate dendritic cell migration through skin--immunomodulatory role of histamine. Allergy 2008;63:13871394.
  • 16
    Morgan RK, McAllister B, Cross L, Green DS, Kornfeld H, Center DM, Cruikshank WW. Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model. Journal of Immunology 2007;178:80818089.
  • 17
    Haas N, Hamann K, Grabbe J, Algermissen B, Czarnetzki BM. Phenotypic characterization of skin lesions in urticaria pigmentosa and mastocytomas. Archieves for Dermatological Research 1995;287:242248.
  • 18
    Huang DR, Wang J, Kivisakk P, Rollins BJ, Ransohoff RM. Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine 2001;93:713726.
  • 19
    Werfel T. The role of leukocytes, keratinocytes, and allergen-specific IgE in the development of atopic dermatitis. J Invest Dermatol 2009;129:18781891.
  • 20
    Campbell EM, Charo IF, Kunkel SL, Strieter RM, Boring L, Gosling J et al. Monocyte chemoattractant protein-1 mediates cockroach allergen-induced bronchial hyperreactivity in normal but not CCR2−/− mice: the role of mast cells. Journal of Immunology 1999;163:21602167.
  • 21
    Hartmann K, Beiglbock F, Czarnetzki BM, Zuberbier T. Effect of CC chemokines on mediator release from human skin mast cells and basophils. International Archives of Allergy and Immunology 1995;108:224230.