Edited By: Hans-Uwe Simon
Effect of asthma treatment on fitness, daily activity and body composition in children with asthma
Version of Record online: 14 JUN 2010
© 2010 John Wiley & Sons A/S
Volume 65, Issue 11, pages 1464–1471, November 2010
How to Cite
Vahlkvist, S., Inman, M. D. and Pedersen, S. (2010), Effect of asthma treatment on fitness, daily activity and body composition in children with asthma. Allergy, 65: 1464–1471. doi: 10.1111/j.1398-9995.2010.02406.x
- Issue online: 14 JUN 2010
- Version of Record online: 14 JUN 2010
- Accepted for publication 11 April 2010
- asthma control;
- body composition;
- cardiovascular fitness;
- physical activity
To cite this article: Vahlkvist S, Inman MD, Pedersen S. Effect of asthma treatment on fitness, daily activity and body composition in children with asthma. Allergy 2010; 65: 1464–1471.
Background: Although several cross-sectional studies have assessed the daily physical activity in children with asthma, the impact of the level of asthma control remains unknown.
Aim: To assess the influence of asthma treatment–induced changes in asthma control on daily physical activity, cardiovascular fitness and body composition in children with asthma.
Methods: Daily accelerometer-measured physical activity, cardiovascular fitness, body composition (percent fat, percent lean tissue and bone mineral density) and a variety of asthma outcomes (to assess the level of asthma control) were measured over 4 weeks in 55 children with newly diagnosed untreated asthma and 154 healthy, sex and age-matched controls. Treatment with inhaled corticosteroids was initiated after the baseline period. All outcome measurements were repeated after 1 year and some also during the year of treatment.
Results: Asthma control improved markedly during the year of treatment. The improvement in control was associated with a significant increase in total daily activity of 2.8 h/week compared with the healthy controls (P < 0.001). In addition, significant increases were seen in moderate-vigorous activity (33 min/week; P = 0.01) and in cardiovascular fitness (1.2 ml O2/min*kg) compared with the healthy controls. The improvement in activity was mainly seen during the last 6 month of the study. No difference was seen between the two groups in changes in percent body fat.
Conclusion: Poorly controlled asthma is associated with reduced physical activity and cardiovascular fitness. Improvement in asthma control is associated with a clinically relevant increase in daily physical activity and cardiovascular fitness.