Allergic diseases, gene–environment interactions
Article first published online: 13 JUN 2011
© 2011 John Wiley & Sons A/S
Special Issue: The 8th Symposium on Specific Allergy (SOSA) 2010.
Volume 66, Issue Supplement s95, pages 10–12, July 2011
How to Cite
Renz, H., Conrad, M., Brand, S., Teich, R., Garn, H. and Pfefferle, P. I. (2011), Allergic diseases, gene–environment interactions. Allergy, 66: 10–12. doi: 10.1111/j.1398-9995.2011.02622.x
- Issue published online: 13 JUN 2011
- Article first published online: 13 JUN 2011
- Accepted for publication 17 March 2011
- Allergic disease;
- gene–environment interaction;
- early intervention;
To cite this article: Renz H, Conrad M, Brand S, Teich R, Garn H, Pfefferle PI. Allergic diseases, gene–environment interactions. Allergy 2011; 66 (Suppl. 95): 10–12.
Allergic asthma develops in part from dysregulation of the innate and adaptive immune functions, particularly an imbalance in the Th2-driven adaptive immune response. This dysregulation is the result of complex interactions between genes and environment. These interactions occur both pre- and postnatally, providing opportunities for early interventions in immunological programming.