ORIGINAL ARTICLE

Allergic diseases, gene–environment interactions

  1. H. Renz,
  2. M. Conrad,
  3. S. Brand,
  4. R. Teich,
  5. H. Garn,
  6. P. I. Pfefferle

Article first published online: 13 JUN 2011

DOI: 10.1111/j.1398-9995.2011.02622.x

Issue

Allergy

Allergy

Special Issue: The 8th Symposium on Specific Allergy (SOSA) 2010.

Volume 66, Issue Supplement s95, pages 10–12, July 2011

Additional Information

How to Cite

Renz, H., Conrad, M., Brand, S., Teich, R., Garn, H. and Pfefferle, P. I. (2011), Allergic diseases, gene–environment interactions. Allergy, 66: 10–12. doi: 10.1111/j.1398-9995.2011.02622.x

Author Information

  1. Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, University Hospital Giessen and Marburg Faculty of Medicine, Philipps University Marburg, Germany

*Harald Renz, Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, University Hospital Giessen and Marburg Faculty of Medicine, Philipps University Marburg, Germany. E-mail: renzh@med.uni-marburg.de

Publication History

  1. Issue published online: 13 JUN 2011
  2. Article first published online: 13 JUN 2011
  3. Accepted for publication 17 March 2011

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Keywords:

  • Allergic disease;
  • gene–environment interaction;
  • early intervention;
  • epigenetics

To cite this article: Renz H, Conrad M, Brand S, Teich R, Garn H, Pfefferle PI. Allergic diseases, gene–environment interactions. Allergy 2011; 66 (Suppl. 95): 10–12.

Abstract

Allergic asthma develops in part from dysregulation of the innate and adaptive immune functions, particularly an imbalance in the Th2-driven adaptive immune response. This dysregulation is the result of complex interactions between genes and environment. These interactions occur both pre- and postnatally, providing opportunities for early interventions in immunological programming.

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