Edited by: Hans-Uwe Simon
Atopic dermatitis: a candidate for disease-modifying strategy
Article first published online: 4 JUN 2012
© 2012 John Wiley & Sons A/S
Volume 67, Issue 8, pages 969–975, August 2012
How to Cite
Bieber T, Cork M, Reitamo S. Atopic dermatitis: a candidate for disease-modifying strategy. Allergy 2012; DOI: 10.1111/j.1398-9995.2012.02845.x.
- Issue published online: 12 JUL 2012
- Article first published online: 4 JUN 2012
- Manuscript Accepted: 13 APR 2012
- atopic dermatitis;
- atopic march;
- disease modification
The concept of disease modification has been introduced to define the therapeutic strategies aimed to break, stop, or reverse the natural course of a chronic invalidating disease. This strategy is tightly related to the biomarker-based stratification of affected patients using genetic and other biological markers. With regard to the progress in understanding the genetic background of atopic dermatitis (AD), its natural history and its pivotal role in the emergence of allergic asthma, the time is mature to foster the research field of biomarkers in AD and to consider the elaboration of disease-modifying strategies in the management of AD with the goal to stop or even reverse the atopic march.