Edited by: Hans-Uwe Simon
Co-factor-enhanced food allergy
Version of Record online: 30 JUL 2012
© 2012 John Wiley & Sons A/S
Volume 67, Issue 10, pages 1316–1318, October 2012
How to Cite
To cite this article: Co-factor-enhanced food allergy. Allergy 2012; 67: 1316–1318., , , , , , , .
- Issue online: 13 SEP 2012
- Version of Record online: 30 JUL 2012
- Manuscript Accepted: 21 JUN 2012
- food allergy;
- nonsteroidal anti-inflammatory drugs
Alcohol, exercise or non-steroidal anti-inflamatory drugs (NSAID) are frequently mentioned as amplifiers of food allergic reactions but only individual cases or small series have been previously published.
Descriptive study including 74 cases of suspected co-factor enhanced food allergy, assessed by skin-prick tests, specific IgE and oral challenges.
Anaphylaxis accounted for 85.1% of reactions. In 99% of cases culprit food allergens were plant-derived, mainly vegetables and cereals. NSAID were involved in 58%, exercise in 52.7% and alcohol in 12.2%. Lipid transfer protein was the most frequently involved allergen.
Co-factor enhanced food allergy should be considered when assessing food, alcohol, exercise and NSAID allergic reactions.