The Niikawa-Kuroki (Kabuki make-up) syndrome in a Moslem Arab child

Authors

  • R. Gillis,

    Corresponding author
    1. Department of Pediatrics, Bikur Cholim General Hospital, affiliated with the Hebrew-University Hadassah Medical School, Jerusalem, Israel
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  • A. Klar,

    1. Department of Pediatrics, Bikur Cholim General Hospital, affiliated with the Hebrew-University Hadassah Medical School, Jerusalem, Israel
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  • E. Gross-Kieselstein

    1. Department of Pediatrics, Bikur Cholim General Hospital, affiliated with the Hebrew-University Hadassah Medical School, Jerusalem, Israel
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M. B. B. S. Department of Pediatrics Bikur Cholim Hospital 5 Strauss St. P.O. Box 492 Jerusalem 91004 Israel

Abstract

The Niikawa-Kuroki “Kabuki Make-Up” syndrome is a rare sporadic malformation syndrome, characterised by severe psychomotor and growth retardation, peculiar facies, including long palpabral fissures and large malformed ears and skeletal abnormalities. We report a 2-year-old Moslem Arab boy with 28 of the 32 originally described features of this syndrome and in addition with hyperelastic joints, hypospadias and scaphocephaly which were not previously described in association with the Kabuki make-up syndrome. This is the fifth reported case of this syndrome in a non-Japanese patient, and the second reported case in a patient of Arab descent.

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