These authors contributed equally to this work.
Adoption and the communication of genetic risk: experiences in Huntington disease
Article first published online: 9 JAN 2011
© 2011 John Wiley & Sons A/S
Volume 81, Issue 1, pages 64–69, January 2012
How to Cite
Bombard, Y., Semaka, A. and Hayden, M. (2012), Adoption and the communication of genetic risk: experiences in Huntington disease. Clinical Genetics, 81: 64–69. doi: 10.1111/j.1399-0004.2010.01614.x
- Issue published online: 12 DEC 2011
- Article first published online: 9 JAN 2011
- Accepted manuscript online: 10 DEC 2010 09:20AM EST
- Received 22 September 2010, revised and accepted for publication 6 December 2010
- genetic information;
- Huntington disease
Bombard Y, Semaka A, Hayden MR. Adoption and the communication of genetic risk: experiences in Huntington disease.
Adoption can present significant challenges when seeking or communicating genetic risk information. Adoption agencies can use genetic information to determine the eligibility of prospective adoptive parents and to establish a child's suitability for adoption. We describe experiences and implications of communicating genetic risk for Huntington disease (HD) in the context of adoption. A secondary analysis was employed using data collected from a cross-sectional survey (n = 233) and two qualitative studies on the psychosocial effects of predictive testing for HD. We demonstrate several ethical and practical challenges in the search for and communication of genetic information for adoptees and their birth relatives. We also found that concern for adoption discrimination was reported by 13.7% of survey respondents (n = 32). Concerns were higher among tested respondents than those who had not been tested (n = 29 vs n = 3, p = 0.010). However, more respondents were concerned about being discriminated based on their family history (FHx) vs their genetic test results (GTR) (concern based on FHx: n = 18 vs based on GTR: n = 1 vs based on both: n =10). These findings contribute to the limited empirical literature by offering evidence on the experiences and implications of communicating genetic risk information in the context of adoption with reference to HD.