SOCIAL AND BEHAVIOURAL RESEARCH IN CLINICAL GENETICS
Primary care physicians' knowledge of and experience with pharmacogenetic testing
Version of Record online: 3 JUL 2012
© 2012 John Wiley & Sons A/S
Volume 82, Issue 4, pages 388–394, October 2012
How to Cite
Primary care physicians' knowledge of and experience with pharmacogenetic testing., , , , .
- Issue online: 11 SEP 2012
- Version of Record online: 3 JUL 2012
- Accepted manuscript online: 14 JUN 2012 12:41PM EST
- Manuscript Accepted: 4 JUN 2012
- Manuscript Revised: 30 MAY 2012
- Manuscript Received: 7 MAR 2012
- National Institutes of Health. Grant Number: R01 GM081416-01A1
- primary care;
It is anticipated that as the range of drugs for which pharmacogenetic testing becomes available expands, primary care physicians (PCPs) will become major users of these tests. To assess their training, familiarity, and attitudes toward pharmacogenetic testing in order to identify barriers to uptake that may be addressed at this early stage of test use, we conducted a national survey of a sample of PCPs. Respondents were mostly white (79%), based primarily in community-based primary care (81%) and almost evenly divided between family medicine and internal medicine. The majority of respondents had heard of PGx testing and anticipated that these tests are or would soon become a valuable tool to inform drug response. However, only a minority of respondents (13%) indicated they felt comfortable ordering PGx tests and almost a quarter reported not having any education about pharmacogenetics. Our results indicate that primary care practitioners envision a major role for themselves in the delivery of PGx testing but recognize their lack of adequate knowledge and experience about these tests. Development of effective tools for guiding PCPs in the use of PGx tests should be a high priority.