The authors have declared that there is no conflict of interest.
The natural history of a genetic subtype of arrhythmogenic right ventricular cardiomyopathy caused by a p.S358L mutation in TMEM43
Version of Record online: 13 AUG 2012
© 2012 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd
Volume 83, Issue 4, pages 321–331, April 2013
How to Cite
The natural history of a genetic subtype of arrhythmogenic right ventricular cardiomyopathy caused by a p.S358L mutation in TMEM43, , , , , , , , , .
- Issue online: 12 MAR 2013
- Version of Record online: 13 AUG 2012
- Accepted manuscript online: 22 JUN 2012 12:03PM EST
- Manuscript Revised: 19 JUN 2012
- Manuscript Accepted: 19 JUN 2012
- Manuscript Received: 7 FEB 2012
- Canadian Institute for Health Research/ACOA
- Genome Canada
- St. Jude Medical Research Grant, Canada
- Department of Health's NIHR Biomedical Research Centres
|cge1919-sup-0001-FigureS1.jpg||JPEG image||2319K||Figure S1. Single family detailing the extensive phenotypic and genealogical data. Key: Black circles and squares are affected females and males, respectively, based on (i) SCD under 50 years, and/or (ii) cardioversion for VT or VF under 50 years, and/or (iii) obligate carrier status, and/or (iv) a p.S358L founder mutation in TMEM43. A line through a symbol indicates death. A plus sign next to a symbol indicates the presence of the TMEM43 p.S358L mutation. The arrowed individual is the original patient .|
|cge1919-sup-0002-FigureS2.pdf||PDF document||116K||Figure S2. Survival in affected male and affected female subjects defined by DNA analysis or obligate carrier status.|
|cge1919-sup-0003-TableS1.docx||Word 2007 document||16K||Table S1. Diagnostic criteria fulfilled in probands from each family: 1994 criteria (1 major and 2 minor).|
|cge1919-sup-0004-TableS2.docx||Word 2007 document||16K||Table S2. Method of diagnosis for 258 affected subjects defined by clinical events, mutation status and pedigree position.|
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