Cytomegalovirus infection and new-onset post-transplant diabetes mellitus


Corresponding author: Manuel Pascual, Transplantation Center, BH10, CHUV, Rue Bugnon 46, 1011 Lausanne, Switzerland.
Tel.: +41 21 314 2404; fax: +41 21 314 2376;


Abstract:  We analyzed data from all consecutive kidney transplant patients at our institution between April 2003 and October 2006. We found 15 cases of late-onset cytomegalovirus (CMV) infection, two of which developed concurrent post-transplant diabetes mellitus (PTDM). In these two cases, PTDM was transient and normal glucose tolerance was achieved after an eight-wk therapeutic course of oral valganciclovir. These findings suggest that CMV infection after organ transplantation may be associated with concurrent PTDM. The distinct causative relationship is yet to be determined.