Evaluation of living related kidney donors in China: policies and practices in a transplant center


Corresponding author: Prof. Li Zeng, Organ Transplantation Institute of PLA, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Road, Huangpu District, Shanghai, 200003, China.
Tel.: +86 021 8188 5754; fax: +86 021 6352 4488; e-mail: zengli111109@yahoo.com.cn


Zhao W-Y, Zhang L, Han S, Zhu Y-H, Wang L-M, Zhou M-S, Zeng L. Evaluation of living related kidney donors in China: policies and practices in a transplant center.
Clin Transplant 2010 DOI: 10.1111/j.1399-0012.2010.01229.x.
© 2010 John Wiley & Sons A/S.

Abstract:  Background:  Rigorous donor evaluation is essential for living related donor kidney transplantation (LRDKT). However, guidelines for living kidney donor evaluation are absent in China. The aim of this study is to describe the initial experience in the living kidney donor evaluation process in a single transplant center in China.

Methods:  The evaluation process of our center is sequentially divided into five steps: outpatient consultation and information, preliminary evaluation, comprehensive evaluation, final informed consent, and ethics committee oversight.

Results:  Between June 2007 and March 2009, 124 potential living donors were evaluated in our center, of whom 82 (66.1%) became effective donors and the remaining 42 (33.9%) were excluded. The exclusion reasons were related to clinical problems in 27 cases, psychosocial problems in seven cases, and suspected organ trading in eight cases.

Conclusion:  Although strongly forbidden by Chinese laws, organ trading remains a threat to the healthy development of LRDKT in China. To prohibit organ trading, the kinship between the donor and recipient should be carefully identified. Guidelines for living donor evaluation appropriate to the actual situation in China should be set up for the sake of safety and to protect the rights and interests of both donors and recipients.