Health-related quality of life and employment among renal transplant recipients

Authors


  • Conflict of Interest: None.

Corresponding author: Marie A. Chisholm-Burns, PharmD, MPH FCCP, FASHP, The University of Arizona College of Pharmacy, 1295 N. Martin Ave., P.O. Box 21202, Tucson, AZ 85721, USA.
Tel.: 1 520 626 2298; fax: 1 520 626 7355; e-mail: chisholm@pharmacy.arizona.edu

Abstract

Chisholm-Burns MA, Erickson SR, Spivey CA, Kaplan B. Health-related quality of life and employment among renal transplant recipients.
Clin Transplant 2011 DOI: 10.1111/j.1399-0012.2011.01541.x.
© 2011 John Wiley & Sons A/S.

Abstract:  Objective:  To examine the relationship between health-related quality of life (HQoL) and employment status in renal transplant recipients (RTRs).

Methods:  Eighty-two RTRs met inclusion criteria: 21–65 yr of age; greater than one yr post-transplant; and received calcineurin inhibitors. A cross-sectional survey was conducted using a demographics questionnaire and the following HQoL instruments: SF-12 Health Survey version 2 (Physical Component Summary [PCS-12] and Mental Component Summary [MCS-12]) and Kidney Transplant Questionnaire (KTQ). Two multivariate logistic regression analyses (SF-12 model and KTQ model) were conducted to determine whether HQoL and demographic variables were independently associated with employment status.

Results:  Seventy-five RTRs were included in the analysis. Compared with employed RTRs, a greater number of unemployed RTRs were non-white, had lower education levels, and had deceased donor transplants (p < 0.05). Employed RTRs had significantly higher SF-12 scores (p < 0.05). In the SF-12 logistic regression model, PCS-12 and education level were significant predictors of employment status (p < 0.05). In the KTQ model, the Fatigue subscale and education level were significant predictors of employment status (p < 0.05).

Conclusions:  Findings suggest higher PCS-12, higher KTQ-Fatigue, and education level are independently associated with employment status. Interventions targeted to improve HQoL, decrease fatigue, and increase education level are discussed.

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