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Pilot study of a pharmaceutical care intervention in an outpatient lung transplant clinic

Authors

  • Jennifer J. Harrison,

    Corresponding author
    1. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada
    • Department of Pharmacy Services, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • June Wang,

    1. Department of Pharmacy Services, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • Julia Cervenko,

    1. Department of Pharmacy Services, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • Leah Jackson,

    1. Department of Pharmacy Services, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • Dipika Munyal,

    1. Department of Pharmacy Services, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • Bassem Hamandi,

    1. Department of Pharmacy Services, Toronto General Hospital, University Health Network, Toronto, ON, Canada
    2. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada
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  • Susan Chernenko,

    1. Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • Josie Dorosz,

    1. Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • Cecilia Chaparro,

    1. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada
    2. Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • Lianne G. Singer

    1. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada
    2. Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada
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  • Conflicts of interest: The authors have no conflicts of interest to declare and no funding support was received for this research.

Corresponding author: Jennifer J. Harrison, BScHon, BScPhm, MSc, Pharmacy Clinical Site Leader, Department of Pharmacy Services, Toronto General Hospital, University Health Network, 585 University Avenue, Clinical Services Building, CSB-076, Toronto, ON, M5G 2N2 Canada.

Tel.: +1 416 340 4800 x6484; fax: +1 416 340 3685; e-mail: jennifer.harrison@uhn.ca

Abstract

Background

Lung transplant recipients have complex drug regimens. Study objectives were to assess drug therapy problems (DTPs), pharmacist recommendations, and patient satisfaction with pharmacist services.

Methods

Using a pharmaceutical care assessment process, pharmacists identified DTPs and made therapeutic recommendations. Number of DTPs identified per pharmacist visit was calculated and compared to standard care visits through retrospective chart review. Potential clinical impact of recommendations was evaluated by blinded clinicians. Patient satisfaction was assessed via survey.

Results

Fifty-five DTPs were identified in 43 patients over 50 pharmacist visits (1.05 ± 1.34 DTPs per visit). In these same patients, rate of DTP identification was 0.51 ± 0.64 DTPs per standard visit in the preceding two-wk period (p = 0.018 vs. pharmacist visit). The most common DTPs identified by the pharmacist were adverse drug effect (27%) and untreated indication (25%). Overall, 62% of pharmacist recommendations were rated very significant or significant. Survey return rate was 58% and satisfaction scores ranged from 3 to 5 out of 5. Review of medications and teaching regarding the use of medications received the most “very satisfied” and “highly important” scores.

Conclusions

Pharmacists can make valuable contributions in a lung transplant clinic setting by identifying DTPs and making recommendations with a positive impact on patient outcomes and satisfaction.

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