Conflict of interest: None.
Repopulation of ganciclovir-resistant cytomegalovirus by wild-type virus
Article first published online: 8 JUL 2012
© 2012 John Wiley & Sons A/S.
Volume 26, Issue 6, pages 949–952, November/December 2012
How to Cite
Drew WL, Liu C. Repopulation of ganciclovir-resistant cytomegalovirus by wild-type virus.
- Issue published online: 6 DEC 2012
- Article first published online: 8 JUL 2012
- Manuscript Accepted: 8 MAY 2012
- ganciclovir resistance;
We report a patient in whom ganciclovir (GCV)-resistant cytomegalovirus (CMV) was replaced by wild-type virus after discontinuation of GCV/valganciclovir and review other similar cases. Repopulation by wild-type virus may occur soon after discontinuation and may be fostered by discontinuing GCV altogether rather than continuing it in combination with foscarnet when treating patients with GCV-resistant CMV disease.