• 1
    Curtin PD. The Atlantic Slave Trade: A Census. Madison, WI: The University of Wisconsin Press, 1969.
  • 2
    US Census Bureau. The black population: 2000.
  • 3
    Parra EJ, Marcini A, Akey J et al. Estimating African American admixture proportions by use of population-specific alleles. Am J Hum Genet 1998: 63: 183951.
  • 4
    Reiner AP, Ziv E, Lind DL et al. Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet 2005: 76: 46377.
  • 5
    Smith MW, Patterson N, Lautenberger JA et al. A high-density admixture map for disease gene discovery in African Americans. Am J Hum Genet 2004: 74: 100113.
  • 6
    Beatty PG, Mori M, Milford E. Impact of racial genetic polymorphism on the probability of finding an HLA-matched donor. Transplantation 1995: 60: 77883.
  • 7
    Just JJ, King MC, Thomson G, Klitz W. African-American HLA class II allele and haplotype diversity. Tissue Antigens 1996: 48: 63644.
  • 8
    Zachary AA, Bias WB, Johnson A, Rose SM, Leffell MS. Antigen, allele, and haplotype frequencies report of the ASHI minority antigens workshops: part 1, African-Americans. Hum Immunol 2001: 62: 112736.
  • 9
    Parham P, Ohta T. Population biology of antigen presentation by MHC class I molecules. Science 1996: 272: 6774.
  • 10
    Robinson J, Waller MJ, Parham P et al. IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex. Nucleic Acids Res 2003: 31: 3114.
  • 11
    Bugawan TL, Mack SJ, Stoneking M, Saha M, Beck HP, Erlich HA. HLA class I allele distributions in six Pacific/Asian populations: evidence of selection at the HLA-A locus. Tissue Antigens 1999: 53: 3119.
  • 12
    Mack SJ, Bugawan TL, Moonsamy PV et al. Evolution of Pacific/Asian populations inferred from HLA class II allele frequency distributions. Tissue Antigens 2000: 55: 383400.
  • 13
    Parham P, Arnett KL, Adams EJ et al. Episodic evolution and turnover of HLA-B in the indigenous human populations of the Americas. Tissue Antigens 1997: 50: 21932.
  • 14
    Cadavid LF, Watkins DI. Heirs of the jaguar and the anaconda: HLA, conquest and disease in the indigenous populations of the Americas. Tissue Antigens 1997: 50: 20918.
  • 15
    Yeager M, Hughes AL. Evolution of the mammalian MHC: natural selection, recombination, and convergent evolution. Immunol Rev 1999: 167: 4558.
  • 16
    Hou L, Tu B, Ling G et al. Strategies for evaluating B*18 allelic diversity by sequence-based typing applied to studies of a population from Singapore and African-Americans. Tissue Antigens 2006: 67: 669.
  • 17
    Cao K, Chopek M, Fernandez-Vina MA. High and intermediate resolution DNA typing systems for Class I HLA-A, -B, -C genes by hybridization with sequence specific oligonucleotide probes (SSOP). Rev Immunogenet 1999: 1: 177208.
  • 18
    Middleton D. HLA-A and -B typing by SSOP. Eur Fed Immunogenet Newslett 1998: 23: 168.
  • 19
    Voorter CE, Swelsen WT., van den Berg-Loonen EM. Intron sequences of HLA-B*73. Tissue Antigens 2001: 57: 4638.
  • 20
    Hurley CK. Sequence-based typing for HLA-A: class I sequencing amplification of exons 2 and 3 based upon Cereb. In: TilanusMG, HansenJA, HurleyCK, eds. IHWG Technical Manual Genomic Analysis of The Human MHC: DNA-Based Typing for HLA Alleles and Linked Polymorphisms 2000: Publication of the 13th International Histocompatibility Working Group Seattle, WA: Fred Hutchinson Cancer Research Center, 2000.
  • 21
    Cereb N, Maye P, Lee S, Kong Y, Yang SY. Locus-specific amplification of HLA class I genes from genomic DNA: locus-specific sequences in the first and third introns of HLA-A, -B, and -C alleles. Tissue Antigens 1995: 45: 111.
  • 22
    Ellis JM, Mack SJ, Leke RFG, Quakyi IA, Johnson AH, Hurley CK. Diversity is demonstrated in class I HLA-A and HLA-B alleles in Cameroon, Africa: description of HLA-A*03012, *2612, *3006 and HLA-B*1403, *4016, *4703. Tissue Antigens 2000: 56: 291302.
  • 23
    Kotsch K, Wehling J, Blasczyk R. Sequencing of HLA class II genes based on the conserved diversity of the non-coding regions: sequencing based typing of HLA-DRB genes. Tissue Antigens 1999: 53: 48697.
  • 24
    Lazaro AM, Steiner NK, Moraes ME et al. Ten novel HLA-DRB1 alleles and one novel DRB3 allele. Tissue Antigens 2005: 66: 3279.
  • 25
    Marsh SG, Albert ED, Bodmer WF et al. Nomenclature for factors of the HLA system, 2004. Tissue Antigens 2005: 65: 30169.
  • 26
    Lancaster A, Nelson MP, Single RM, Meyer D, Thomson G. PyPop: a software framework for population genomics: analyzing large-scale multi-locus genotype data. In: AltmanRB, DunkerK, HunterL, JungT, KleinT, eds. Pacific Symposium on Biocomputing 8. Singapore: World Scientific, 2003: 51425.
  • 27
    Lancaster AK, Single RM, Nelson MP, Solberg O, Thomson G. 14th international HLA and immunogenetics workshop biostatistics and anthropology/human genetic diversity joint report. Chapter 3. PyPop update-a software pipeline for large-scale multi-locus population genomics. Tissue Antigens 2007: in press.
  • 28
    Guo SW, Thompson EA. Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 1992: 48: 36172.
  • 29
    Meyer D, Single R, Mack SJ et al. 13th IHWS anthropology/human genetic diversity joint report. Chapter 4. Single locus polymorphism of classical HLA genes. In: HansenJA, DupontB, eds. HLA 2004 Immunobiology of The Human MHC Seattle: IHWG Press, in press.
  • 30
    Ewens W. The sampling theory of selectively neutral alleles. Theor Pop Biol 1972: 3: 87112.
  • 31
    Watterson G. The homozygosity test of neutrality. Genetics 1978: 88: 40517.
  • 32
    Slatkin M. An exact test for neutrality based on the Ewens sampling distribution. Genet Res 1994: 64: 714.
  • 33
    Slatkin M. A correction to the exact test based on the Ewens sampling distribution. Genet Res 1996: 68: 25960.
  • 34
    Salamon H, Klitz W, Easteal S et al. Evolution of HLA class II molecules: allelic and amino acid site variability across populations. Genetics 1999: 152: 393400.
  • 35
    Dempster A, Laird N, Rubin D. Maximum likelihood estimation from incomplete data using the EM algorithm. J R Stat Soc 1977: 39: 138.
  • 36
    Excoffier L, Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 1995: 12: 9217.
  • 37
    Hedrick PW. Gametic disequilibrium measures: proceed with caution. Genetics 1987: 117: 3314.
  • 38
    Lewontin RC. The interaction of selection and linkage. II. Optimum models. Genetics 1964: 50: 75782.
  • 39
    Lewontin RC. On measures of gametic disequilibrium. Genetics 1988: 120: 84952.
  • 40
    Cramer H. Mathematical Methods of Statistics. Princeton, NJ: University Press, 1946.
  • 41
    Excoffier L, Laval G, Schneider S. Arlequin (version 3.0): an integrated software package for population genetics data analysis. Bioinformatics Online 2005: 1: 4750.
  • 42
    Cao K, Moormann AM, Lyke KE et al. Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci. Tissue Antigens 2004: 63: 293325.
  • 43
    Cao K, Hollenbach J, Shi X, Shi W, Chopek M, Fernandez-Vina MA. Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. Hum Immunol 2001: 62: 100930.
  • 44
    Bodmer JG, Marsh SGE, Albert ED et al. Nomenclature for factors of the HLA system, 1996. Tissue Antigens 1997: 49: 297321.
  • 45
    Bugawan TL, Klitz W, Blair A, Erlich HA. High-resolution HLA class I typing in the CEPH families: analysis of linkage disequilibrium among HLA loci. Tissue Antigens 2000: 56: 392404.
  • 46
    Belich MP, Madrigal JA, Hildebrand WH et al. Unusual HLA-B alleles in two tribes of Brazilian Indians. Nature 1992: 357: 3269.
  • 47
    Klitz W, Thomson G, Baur MP. Contrasting evolutionary histories among tightly linked HLA loci. Am J Hum Genet 1986: 39: 3409.
  • 48
    Mori M, Beatty PG, Graves M, Boucher KM, Milford EL. HLA gene and haplotype frequencies in the North American population-the National Marrow Donor Program Donor Registry. Transplantation 1997: 64: 101727.
  • 49
    Williams F, Meenagh A, Single R et al. High resolution HLA-DRB1 identification of a Caucasian population. Hum Immunol 2004: 65: 6677.
  • 50
    Bjorkman PJ, Parham P. Structure, function, and diversity of class I major histocompatibility complex molecules. Annu Rev Biochem 1990: 59: 25388.
  • 51
    Hurley CK, Wagner JE, Setterholm MI, Confer DL. Advances in HLA: practical implications for selecting adult donors and cord blood units. Biol Blood Marrow Transplant 2006: 12: 2833.