14th International HLA and Immunogenetics Workshop: Report on joint study on canine DLA diversity


Lorna J. Kennedy
Centre for Integrated Genomic Medical Research
University of Manchester
Tel: 44 161 275 7316
Fax: 44 161 275 1617
e-mail: Lorna.Kennedy@manchester.ac.uk


The canine DLA diversity component of the 14th International HLA and Immunogenetics (IHI) Workshop had three main aims: i) to establish the range of DLA class II (DRBI, DQA1, DQB1) diversity and their distribution in dog breeds, ii) to identify DLA class II haplotypes by segregation in families and iii) to examine DLA class II associations with disease susceptibility. Over 1600 dogs from seven participating laboratories were typed for three DLA class II loci as part of the workshop. Standard sequence-based typing methods were used, and all the data were of high quality.