Immune response gene polymorphisms in unrelated donor hematopoietic cell transplantation


Mari Malkki, PhD
Fred Hutchinson Cancer Research Center
110 Fairview Ave N, D4-100
Seattle, WA 98109
Tel: +1 206 667 5797
Fax: +1 206 667 2917


Immune response genes (IRG) play an important role in inflammation and control of infection after allogeneic transplantation. The International Histocompatibility Working Group (IHWG) in hematopoietic cell transplantation took a candidate gene approach to define the risks associated with genetic variation for a panel of well-characterized IRG.