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Keywords:

  • alleles;
  • antigens;
  • histocompatibility;
  • HLA;
  • serological equivalents;
  • serology

Abstract

  1. Top of page
  2. Abstract
  3. WHO nomenclature: allele and serologic assignments
  4. International Cell Exchange, UCLA
  5. National Marrow Donor Program
  6. Neural network
  7. Acknowledgments
  8. References

The 2008 report of the human leukocyte antigen (HLA) data dictionary presents serologic equivalents of HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, and -DQB1 alleles. The dictionary is an update of the one published in 2004. The data summarize equivalents obtained by the World Health Organization Nomenclature Committee for Factors of the HLA System, the International Cell Exchange, UCLA, the National Marrow Donor Program, recent publications, and individual laboratories. The 2008 edition includes information on 832 new alleles (685 class I and 147 class II) and updated information on 766 previously listed alleles (577 class I and 189 class II). The tables list the alleles with remarks on the serologic patterns and the equivalents. The serological equivalents are listed as expert assigned types, and the data are useful for identifying potential stem cell donors who were typed by either serology or DNA-based methods. The tables with HLA equivalents are available as a searchable form on the IMGT/HLA database Web site (http://www.ebi.ac.uk/imgt/hla/dictionary.html).

The 2008 edition of the human leukocyte antigen (HLA) data dictionary is the fifth update; previous versions have been published in 1997, 1999, 2001, and 2004 (1–4). The HLA data dictionary is aimed at identifying the serological types associated with each HLA-A, -B, -C, -DRB1, and -DQB1 allelic product. The dictionary is a reference to help with the identification of potential hematopoietic stem cell (HSC) donors. The serologic equivalents of the DNA-defined alleles can be used to identify potential donors listed in unrelated donor registry databases and umbilical cord banks who have been typed by serology. Although the majority of laboratories use DNA-based methods for typing today, there is a significant number of HLA assignments in registries and banks that have been determined by serology-based methods. For example, in the database of almost 7 million volunteers of the National Marrow Donor Program (NMDP) in the United States, the percent of serologic assignments for volunteer donors is still significant, with 45% of the HLA-A and -B loci, 31% of the -C locus, 4% of the -DRB1 locus, and 37% of the -DQB1 locus assignments defined serologically. The availability of serologic equivalents allows potentially matched volunteers typed by serology to be matched to DNA-typed patients.

The number of newly identified HLA alleles grows each year and since the 2004 publication, 832 new HLA alleles have been added, including 235 HLA-A, 310 -B, 140 -C, 116 -DRB1, 9 -DRB3/4/5, and 22 -DQB1 alleles. Information has also been updated for 766 previously listed alleles numbering 158 HLA-A, 303 -B, 116 -C, 133 -DRB1, 13 -DRB3/4/5, and 43 -DQB1 alleles. This edition of the dictionary includes all newly defined four-digit alleles displayed in the IMGT/HLA database (5) to the end of July 2007 in Tables 1–6.

Table 1.  HLA-A alleles and their serologic designationsg
HLA alleleExpert assignedWHO assignedInternational Cell Exchange, UCLANMDPIHWS13 dataNNComments
Assigned type [%]Cells testedAssigned type [%]Cells testedAssignmentCells testedAssigned type >0.55
  • NT, not tested; NN, neural network; HLA, human leukocyte antigen; WHO, World Health Organization; NMDP, National Marrow Donor Program.

  • a

    Updated International Cell Exchange, UCLA.

  • b

    WHO assignment based on dictionary data.

  • c

    Updated NMDP data. In some cases, the information reported in previous dictionaries has changed. Cells have been excluded from this study in some cases because their HLA typing has changed.

  • d

    The allele has been identified but serology not informative.

  • e

    Not assigned; see comment column for predictions >0.20.

  • f

    If a primary specificity is provided by the NN, other specificities >0.4 are shown in the comments column.

  • g 
A*0101A1A1A1 [98–100]34aA1 [99]5612A1113The allele was used for training of the NN – A1 
A*01010102NNot expressedNullNT 
A*0102A1A1A1 [95]129Training – A1 
A*0103A1A1bA1 [99]2A1 [94]c33A15Training – A1 
A*0104NNot expressedNullcd1NT 
A*0106A1A1 [100]c3A1 
A*0107A1A1A1 
A*0108A1A1A1Normal A1
A*0109A1A1 
A*0110A1A1 
A*0111NNot expressedNullNT 
A*0112UndefinedNot assignedeNN: A1
A*0113A1A1 
A*0114A1A1 
A*0115NNot expressedNullNT 
A*0116NNot expressedNullNT 
A*0117A1A1 
A*0118NNot expressedNullNT 
A*0119A1A1Not assignedeNN: A1
A*0120A1A1 
A*0121A1A1 
A*0122NNot expressedNullNT 
A*0123A1A1 
A*0124A1A1 
A*0125A1A1 
A*0126A1A1 
A*0127NNot expressedNullNT 
A*0201A2A2A2 [99–100]117aA2 [98]6315A2230Training – A2 
A*02010102LLow A2Low A2Identical to A*0201Significantly reduced or low cell surface expression
A*0202A2A2A2 [100]a7A2 [81]859A28Training – A2ihw13: variant serum pattern
A*0203A203/A2A203A2 [99–100]a10A2 [64]472A20312A2ihw13: very short A2
A*0204A2A2A2 [77]28A2 
A*0205A2A2A2 [100]5A2 [81]462A210Training – A2 
A*0206A2A2A2 [99–100]a47A2 [68]636A224Training – A2 
A*0207A2A2A2 [100]a15A2 [80]135A217Training – A2 
A*0208A2A2A2 [100]c7A2 
A*0209A2A2A2 [100]c10A2 
A*0210A210/A2A210A2 [100]c10A2 
A*0211A2A2A2 [99]1A2 [74]228A217A2ihw13: short A2
A*0212A2A2A2 [100]c10A21A2 
A*0213A2A2A2 [100]c17A2 
A*0214A2A2A2 [100]c7A2 
A*0215NNot expressedNullcNT 
A*0216A2A2A2 [81]c16A2 
A*0217A2A2A2 [73]51A22A2 
A*0218A2A2A2 [100]c1A2 
A*0219A2Blank [100]c1A2 
A*0220A2A2A2 [100]c26A2Normal A2
A*0221A2A2A2 
A*0222A2A2A2 [100]c21A2 
A*0224A2A2A2 [100]c11A2 
A*0225A2A2A2 
A*0226A2A2 [100]c3A2 
A*0227A2A2 [100]c1A2 
A*0228A2A2 [100]c1A2 
A*0229A2A2A2 [100]c2A2 
A*0230A2A2 [100]c7A2 
A*0231A2A2A2 
A*0232NNot expressedNullNT 
A*0233A2A2 [100]c3A2 
A*0234A2A2A2 
A*0235A2A2A2 [100]c8A22A2Normal A2
A*0236A2A2 [100]c1A2Normal A2
A*0237A2A2 
A*0238A2A2 [67], blank [33]c3A2Normal A2
A*0239A2A2 [100]c1A2 
A*0240A2A2 
A*0241A2A2A2 
A*0242A2A2A2 
A*0243NNot expressedNullNT 
A*0244A2/blankBlank [100]c6A2 
A*0245A2A2 [100]c2A2 
A*0246A2A2A2 
A*0247A2A2 
A*0248A2A2A2x9, few A23 + 24 sera reactive
A*0249A2A2A21A2Normal A2. The HLA club cell exchange: nine laboratories performing serology
A*0250A2A2A2 
A*0251A2A2 
A*0252A2A2 
A*0253NNot expressedNullNT 
A*0254A2A2 
A*0255A2/A28Not assignedeNN: A2, A28, A69
A*0256A2A2Short A2
A*0257A2A2 
A*0258A2A2 
A*0259A2A2A2 
A*0260A2A2 [100]c3A2 
A*0261A2A2 
A*0262A2A2A2 variant; A2x69 variant
A*0263A2A2 [100]c1A2 
A*0264A2cd1A2 
A*0265A2/A19A2/19Not assignedeNN: A74
A*0266A2A2A2 [100]c2A2 
A*0267A2A2A2 
A*0268A2A2A2 
A*0269A2A2 
A*0270A2A2A2 
A*0271A2A2A2 
A*0272A2A2A2 
A*0273A2A2A2 
A*0274A2A2A2 
A*0275A2A2 
A*0276A2A2 
A*0277A2A2A2 
A*0278UndefinedA2Not assignedeNN: A69, A28
A*0279A2A2A2 
A*0280A2A2 
A*0281A2A2 [100]c1A2 
A*0282NNot expressedNullNT 
A*0283NNot expressedNullNT 
A*0284A2A2 
A*0285A2A2 [100]c1A2 
A*0286A2A2 
A*0287A2A2 
A*0288NNot expressedNullNT 
A*0289A2A2A2 
A*0290A2A2A2 
A*0291A2A2 
A*0292A2A2 
A*0293A2A2 
A*0294NNot expressedNullNT 
A*0295A2A2A2 
A*0296A2A2 
A*0297A2A2A2 
A*0299A2A2 
A*9201A2A2 
A*9202A2A2 
A*9203A2A2 
A*9204A2A2 
A*9205A2A2A2 
A*9206A2A2 
A*9207A2A2 
A*9208A2A2 
A*9209A2A2 
A*9210A2A2 
A*9211A2A2 
A*9212A2A2 
A*9213NNot expressedNullNT 
A*9214A2A2 
A*9215A2A2 
A*9216A2A2 
A*9217A2A2 
A*9218A2A2 
A*9219A2A2 
A*9220A2A2 
A*9221A2A2 
A*9222A2A2 
A*9223A2A2 
A*9224A2A2 
A*9225NNot expressedNullNT 
A*9226A2A2 
A*0301A3A3A3 [98–100]a44A3 [99]3504A3106Training – A3 
A*03010102NNot expressedNull NT 
A*0302A3A3A3 [99–100]2A3 [78]342A33Training – A3 
A*0303NNot expressedNullNT 
A*0304A3A3cd1A3 
A*0305A3/blankA3Blank [100]c5Blank1A3ihw13: only reactive with some A3 + 11 and A3 + 19 + 34 sera; normal A3
A*0306A3/blankA3/blank1A3ihw13: very short A3
A*0307A3A3 [75]c4A3 
A*0308A3A3 [100]c4A3 
A*0309A3cd1A31A3 
A*0310A3/blankA3A3 sera negative, only A3 + 30 + 31 + 33 monoclonal antibodie positive
A*0311NNot expressedNullNT 
A*0312A3A3 
A*0313A3A3 
A*0314A3A3 
A*0315A3A3 
A*0316A3A3 
A*0317A3A3 
A*0318UndefinedA1 
A*0319A3A3 
A*0320A3A3A3 
A*0321NNot expressedNullNT 
A*0322A3A3 
A*0323A3A3 
A*0324A3A3A3 
A*0325A3A3 
A*0326A3A3 
A*0327A3A3 
A*0328A3A3 
A*0329A3A3 
A*0330A3A3 
A*1101A11A11A11 [99–100]a77A11 [99]2530A11118Training – A11 
A*1102A11A11A11 [99]1A11 [76]42A118A11ihw13: short A11
A*1103A11A11A11 [82]c17A111A11 
A*1104A11A11A11 [63–69]2A11 [75], blank [25]c8A11Short A11; normal A11
A*1105A11A11A11 [80]c5A11Short A11; 3/31 A11 sera reactive
A*1106A11A11 [100]c2A11 
A*1107A11A11A11Normal A11
A*1108A11A11A11Short A11
A*1109A11A11A11 [100]c1A11 
A*1110A11A11Blank [100]c1A10 
A*1111UndefinedNot assignedeNN: A11
A*1112A11A11A11 [100]c3A11Normal A11
A*1113A11A11A11Short A11
A*1114A11A11A11Short A11, like A11.2
A*1115A11A11A11 
A*1116A11A11 
A*1117UndefinedNot assignedeNN: A11
A*1118UndefinedNot assignedeNN: A11
A*1119A11A11A11 
A*1120A11A11 
A*1121NNot expressedNullNT 
A*1122A11A11 
A*1123A11A11 
A*1124A11A11 
A*1125A11A11A11 
A*1126A11A11 
A*1127UndefinedNot assignedeNN: A11, A1
A*1128A11A11 [100]c1A11 
A*1129A11A11 
A*1130A11A11 
A*1131A11A11 
A*1132A11A11 
A*2301A23A23(9)A23 [95–100]a29A23 [95], A24 [1]5119A2342Training – A9, A23 
A*2302A23A23 [100]c5A23 
A*2303A23A9 [100]c1A23 
A*2304A23A23(9)bA231A23ihw13: short A23, negative with A9 + 80 (+1) sera
A*2305A23A23 [100]c2A23 
A*2306A23A23 
A*2307NNot expressedNullNT 
A*2308NNot expressedNullNT 
A*2309A23A23 
A*2310A23A23 
A*2311NNot expressedNullNT 
A*2312A23A23(9)A23 
A*2313A23A23 
A*2314A23A23 
A*2315A23A23 
A*2316A23A23 
A*2402A24A24(9)A24 [97–100]99aA24 [97], A2403 [1]3098A24146Training – A9, A24 
A*24020102LLow A24Low A24(9)A24 [0–5]a3Blank1Identical to A*2402Significantly reduced or low cell surface expression
A*2403A2403/A24A2403A24 [66–68], A2403 [29–31]a10A24 [55], blank [20], A9 [4], A2403 [1]282A245A24ihw13: short A24, negative with A9 + 80 (+1) sera
A*2404A24A24(9)A24 [62], blank [25], A2403 [13]c8A9 
A*2405A9A9A23 [67–70], A24 [14–19]a2A24 [45], A23 [50]c20A24 
A*2406A24A24(9)A24 [67], blank [33]c3A245A24 
A*2407A24A24(9)A24 [99–100]a21A24 [59]320A2417Training – A9, A24 
A*2408A24A24(9)A24 [47], blank [26]30A24Short A24, similar to A2403
A*2409NNot expressedNullBlank [100]c2NT 
A*2410A2403/A24A2403A24 [42], A9 [9], blank [16], A2403 [3]32A241A24A2403; ihw13: short A24
A*2411NNot expressedNullBlanka1Blank [100]c2NT 
A*2413A24A24(9)cd1A24 
A*2414A24A24(9)A24 [82]c11A24 
A*2415A24cA24 
A*2417A24A24(9)bA24 [82]c11A243A24ihw13: short A24
A*2418A24/A3A24(9)/A3A9fA2403x3; short A24 with most A3 and A9 reactive; NN: A24
A*2419A9A9A24Very short A9
A*2420A24A24(9)bA24 [100]c9A241A24 
A*2421A24/A9A24(9)A24A9variant; A24 sera negative
A*2422A24A9A24 [83]c6A241A24ihw13: short A24, negative with A9 + 80 (+1) sera; A2403 like
A*2423A24A2403A24 [100]c11A24A2403
A*2424A9A9fNN: A23
A*2425A24A24 [100]c13A24 
A*2426A24A24 [100]b2A24 
A*2427A24A24(9)bA241A24ihw13: short A24
A*2428A9A24(9)A24 [50], A9 [50]c2Not assignedeNN: A9, A24, A2
A*2429A24A24 [100]c1A24 
A*2430A24A24 
A*2431A24A24 
A*2432A24A24 [100]c4A24 
A*2433A2403/A24A2403A24 [99–100]a4A24 [100]c4A241A24A2403
A*2434A24A24 
A*2435A24A24 
A*2436NNot expressedNullNT 
A*2437A24A24A24 [94–97]a4A24 [100]c1A24 
A*2438A24A24 
A*2439A24A24 
A*2440NNot expressedNullNT 
A*2441A24A24 
A*2442A24A24 
A*2443A24A24(9)A24 
A*2444A9A9fNN: A24
A*2445NNot expressedNullNT 
A*2446A24A24 
A*2447A24A24 
A*2448NNot expressedNullNT 
A*2449A24A24 
A*2450A24A24 
A*2451A24A24 
A*2452A24A24 
A*2453A24A24 
A*2454A24A24 
A*2455A24A24 
A*2456A24A24 
A*2457A24A24 
A*2458A24A24(9)A24 
A*2459A24A24 
A*2460NNot expressedNullNT 
A*2461A24A24 
A*2462A24A24 
A*2463A24A24 
A*2464A24A24 
A*2465A24A24 
A*2466A24A24 
A*2467A24A24 
A*2468A24A24 
A*2469A24A24 
A*2470A24A24 
A*2471A24A24 
A*2472A24A24 
A*2473A24A24 
A*2474A24A24 
A*2475A24A24 
A*2476A24A24(9)A24 
A*2477A24A24 
A*2478A24A24(9)A24 
A*2479A24A24 
A*2501A25A25(10)A25 [94–99]6aA25 [95], A10 [2]1375A2518Training – A10, A25 
A*2502A25A25(10)bA25 [88]c8A251A25Normal A25
A*2503A25A25 [100]c2A25 
A*2504A25A25 
A*2505A25A2 [100]c1 A25 
A*2506A25 A25 
A*2601A26A26(10)A26 [95–97]a27A26 [97], A10 [2]1730A2647Training – A10, A26 
A*2602A26A26(10)A26 [91–97]a3A26 [81]31A262Training – A10, A26 
A*2603A26A26(10)A26 [92–98]a11A26 [68], A10 [8]38A265Training – A10, A26ihw13: short A26
A*2604A26A26(10)A10 [50], blank [50]c2A26 
A*2605A26A26(10)A26 [90], A25 [10]c10A26 
A*2606A26A26(10)A26 [100]c1A26 
A*2607A26A26(10)A26 [100]c1Not asssignedeNN: A43, A10, A26
A*2608A26A26(10)A26 [95]65A263A26ihw13: short A26, similar to A*2603; normal A26
A*2609A26A26(10)bA26 [33], A10 [33], A34 [33]c3A262A26ihw13: short A26
A*2610A10A10A26Short A26, A10 variant
A*2611NNot expressedNullNT 
A*2612A26A26 [75], A34 [25]c4A26 
A*2613A26A26 [100]c3A26NN: A66
A*2614A26A26 
A*2615A10A10bA102A26ihw13: only few A10 sera reactive, may be typed as blank; A blank
A*2616A26A26 [100]c1A26 
A*2617A26A26 
A*2618A10Blank [100]c1A10fNN: A26
A*2619UndefinedNot assignedeNN: A43, A10
A*2620A26A26 
A*2621A26A26 
A*2622A26A26(10)A26 
A*2623A26A26(10)A26 
A*2624A26A26 
A*2625NNot expressedNullNT 
A*2626A26A10A26 
A*2627A26A26 
A*2628A26A26 
A*2629A26A26(10)A26 
A*2630A26A26 
A*2631A26A26 
A*2632A26A26 
A*2633A26A26 
A*2634A26A26 
A*2635A26A26 
A*2901A29A29(19)A29 [98]a1A29 [96]115A2910Training – A29 
A*29010102NNot expressedNullNT 
A*2902A29A29(19)A29 [98–100]a17A29 [99]1488A2928Training – A29 
A*2903A29A29 [100]c4A29 
A*2904A29A29 [100]c1A29 
A*2905A29A29 
A*2906A29A29 
A*2907A29A29 
A*2908NNot expressedNullNT 
A*2909A29A29 
A*2910A29A29(19)A29 [100]c2A29 
A*2911A29A29 
A*2912A29A29 
A*2913UndefinedNot assignedeNN: A32, A29
A*2914UndefinedNot assignedeNN: A29, A30
A*2915A29A29 
A*2916A29A29(19)A29 
A*3001A30A30(19)A30 [97–100]a25A30 [89], A31 [3], blank [3], A19 [1]2895A3028Training – A30 
A*3002A30A30(19)A30 [96–100]a17A30 [93], A31 [2], A19 [1]2124A3025Training – A30 
A*3003A30A30(19)A30 [83], blank [17]c6A30 
A*3004A30A30(19)A30 [97–98]a2A30 [94]85A307Training – A30 
A*3006A30cd1A30 
A*3007A30A30 [100]c2A30 
A*3008A30A30 
A*3009A30A30 [100]c3A301A30ihw13: very short A30, only broad A19 sera reactive
A*3010A30A30 [100]c10A30 
A*3011A30A30(19)A30 
A*3012A30A30 
A*3013A30A30 
A*3014LA30Low A30(19)A30Significantly reduced or low cell surface expression
A*3015A30A30(19)A30 
A*3016A30A30 
A*3017A30A30(19)A30 
A*3018A30A30(19)A30 
A*3019A30A30 
A*3020A30A30 
A*3021A30A30 
A*3022A30A30 
A*3101A31A31(19)A31 [94–98]a23A31 [90], A30 [3], A19 [1]3517A3158Training – A31 
A*3102A31A31(19)bA31 [100]c17A31 
A*3103A31A31 [100]c2A31 
A*3104A31A31(19)A31 
A*3105A31A31(19)A31 
A*3106A31A31 
A*3107UndefinedNot assignedeNN: A32, A23, A9
A*3108A31/A24A32 [100]c1Not assignedeA31x24; previously A*2416; NN: A23, A9, A32
A*3109A31A31 [100]c3A31Bw4 motif present
A*3110A31A31(19)Not assignedeNN: A32
A*3111A31A31 
A*3112A31A31(19)A31 
A*3113A31A31 
A*3114NNot expressedNullNT 
A*3115A31A31 
A*3116A31A31 
A*3117A31A31 
A*3118A31A31 
A*3201A32A32(19)A32 [97–99]a20A32 [94]3441A3250Training – A32 
A*3202A32A32(19)A32 [100]c3Not assignedeNN: A32
A*3203A32A32 [67], blank [33]c3A32 
A*3204A32/A3A3 [75], A19 [13], A32 [13]c8A‘3204’1Not assignedeA3 with most A32 sera reactive (ihw13); NN: A32, A3
A*3205A32A32 
A*3206A32A32 
A*3207A32A32 [100]c1A32 
A*3208A32A32 [100]c2A32 
A*3209A32A32 
A*3210A32A32 
A*3211QA32A32Not expected to be expressed
A*3212A32A32 
A*3213A32A32 [100]c1A32 
A*3214A32A32(19)A32 
A*3215A32A32 
A*3301A33A33(19)A33 [97–100]10aA33 [87], A19 [3], blank [4]687A3319Training – A33 
A*3303A33A33(19)A33 [95–100]a36A33 [95], A34 [1]887A3327Training – A33 
A*3304A33A33 [50], blank [50]c2A33 
A*3305A33A33(19)A33 [92]c13A331A33ihw13: short A33
A*3306A33cd1A33 
A*3307A33A33 
A*3308UndefinedA33(19)Not assignedeNN: A31, A33
A*3309UndefinedA19Not assignedeNN: A31, A33
A*3310A33A33 
A*3311A33A33 
A*3312A33A33 
A*3313UndefinedNot assignedeNN: A33
A*3401A34A34(10)A34 [93–98]a30A34 [67], A26 [10], A10 [5], A66 [4], A33 [2], blank [7]269A3425Training – A10, A34ihw13: distinct pattern from A*3402
A*3402A34A34(10)A34 [92–95]a11A34 [89], A33 [4], A26 [3], A10 [2]996A3411Training – A10, A34ihw13: distinct pattern from A*3401
A*3403A34A34 
A*3404A34A34(10)A342A34ihw13: short A34, with some A11 and A19 sera reactive; A34 variant with some A10 sera reactive
A*3405A34A34 
A*3406A10 A10fNN: A34
A*3407A34 A34 
A*3408A34A10 [100]c1 A34 
A*3601A36A36A36 [85–93], A1 [5–8]a5A36 [68], A1 [16], blank [6]807A367Training – A36 
A*3602A36A36 
A*3603A36A36A36 
A*3604A36A36bA362A36 
A*4301A43A43A26 [50], A10 [13], A34 [13], A19 [13], blank [13]c8Training – A43 
A*6601A66A66(10)A66 [37–59], A‘6601’ [22–42], A26 [15–18], A10 [2–7]a14A26 [61], A66 [20], A34 [8], A10 [3], A25 [1]799A6619Training – A10, A66ihw13: A‘6601’ pattern – different from A‘6602’; reactive with A34 + 66 sera
A*6602A66A66(10)A‘6602’ [35–65], A66 [15–42], A34 [7–18], A10 [4]a8A66 [38], A34 [27], A10 [10], A74 [5], A26 [4]205A662A66ihw13: A‘6602’, short A66
A*6603A10A10A66 [32], A34 [18], A10 [7], A26 [7]28A10fShort A10; NN: A26
A*6604A66A66 
A*6605A26A26 [100]c1A26 
A*6606A66A66(10)A66 
A*6801A68A68(28)A68 [53–68], A28 [31–45]a34A28 [63], A68 [27]2736A6849Training – A28, A68 
A*6802A68A68(28)A68 [55–65], A28 [32–43]a15A28 [72], A68 [19], A69 [1]2327A6818Training – A28, A68 
A*6803A68A68(28)bA68 [47–66], A28 [34–48]a16A28 [63], A68 [28]202A684A68 
A*6804A68A68(28)A28 [75], A68 [25]c4A68 
A*6805A68A68(28)A28 [53], A68 [29]59A281A68ihw13: possibly A68, but cell also A2 positive
A*6806A68A28 [50], A68 [50]c2A68 
A*6807A68Blank [100]c1A68 
A*6808A68A68(28)A68 [38–45], A28 [53]2A28 [100]c2A68 
A*6809A68A68 [100]c1A68 
A*6810A68A28bBlank [50], A1 [50]c2A281A68ihw13: possibly A68, but cell also A2 positive
A*6811NNot expressedNullNT 
A*6812A28A28A28 [50], blank [50]c6A68Short A28
A*6813A68A68 
A*6814A68A68 
A*6815A68A68 
A*6816A68A68(28)A68 
A*6817A68A28bA28 [100]c1A281A68ihw13: possibly A68, but cell also A2 positvie
A*6818NNot expressedNullNT 
A*6819A68A28 [100]c1A68 
A*6820A68A68 
A*6821A68A68 
A*6822A68A68 
A*6823A68A68 [100]c1A68 
A*6824A68A68 
A*6825A68A28 [100]c1A68 
A*6826A68A28A68 
A*6827A68A68 
A*6828A68A68 
A*6829A68A68 
A*6830A68A68 
A*6831A68A68 
A*6832A68A68 
A*6833A68A68(28)A68 
A*6834A68A68 
A*6835A68A68 
A*6836A68A68(28)A28fNN: A68
A*6837A68A68 
A*6838A68A68 
A*6839A68A68 
A*6840A68A68 
A*6901A69A69(28)A69 [40–70], A28 [33–49]a3A28 [56], A69 [7], A2 [6], A68 [3]289A696Training – A28, A69 
A*7401A74A74(19)A74 [72–95]a13A74 [40], A19 [11], blank [36]115A7411Training – A74 
A*7402A74A74(19)Blank [50], A74 [17], A33 [17], A31 [17]c6A74 
A*7403A74A74(19)A74 [89–91]5Blank [72], A74 [17]29A744A74 
A*7404A74A74 [100]c1A74 
A*7405A74Blank [100]c1A74 
A*7406A74A74(19)A74 [100]c1A741A74 
A*7407A74A74(19)A74 
A*7408A74A74 
A*7409A74A74 [33], A33 [33], blank [33]c3A74 
A*7410Undefined Not assignedeNN: A74
A*7411A74cd1 A74 
A*7412NNot expressedNull NT 
A*8001A80A80A80 [68–88], A36 [0–3]11Blank [77], A80 [10], A36 [2], A1 [1]505A809Training – A80ihw13: difficult to type next to A1 or A24
Table 2.  HLA-B alleles and their serologic designationsg
HLA alleleExpert assignedWHO assignedInternational Cell Exchange, UCLANMDPIHWS13 dataNNComments
Assigned type [%]Cells testedAssigned type [%]Cells testedAssignmentCells testedAssigned type >0.55
  • NT, not tested; NN, neural network; HLA, human leukocyte antigen; WHO, World Health Organization; NMDP, National Marrow Donor Program.

  • a

    Updated International Cell Exchange, UCLA.

  • b

    Updated NMDP data. In some cases the information reported in previous dictionaries has changed. Cells have been excluded from this study in some cases because their HLA typing has changed.

  • c

    WHO assignment based on dictionary data.

  • d

    The allele has been identified but serology not informative.

  • e

    Not assigned; see comment column for predictions >0.20.

  • f

    If a primary specificity is provided by the NN, other specificities >0.4 are shown in the comments column.

  • g 
B*0702B7B7B7 [98–100]a32B7 [98]10,841B783Training – B7 
B*0703B703/B7B703B7 [94]b17B703, B7, blank1B7Short B7, B7 + 42 sera reactive, B7 + 22 sera negative
B*0704B7B7B7 [89]44B72Training – B7 
B*0705B7B7B7 [91–97]a4B7 [95]42B76Training – B7 
B*0706B7B7B7 [94–95]4B7 [96]23B7 
B*0707B7B7B7 [93]b15B7 
B*0708B7B7cB71B7Short B7, negative with B7 + 22 sera, similar to B703
B*0709B7B7B7 [97–98]2B7 [100]b8B72B7 
B*0710B7B7cB7 [92]b12B72B7 
B*0711B7B7B7 
B*0712B7B7cB7 [100]b5B7 
B*0713B7/blankBlank [100]b3B7 
B*0714B7B7cB7 [100]b10B71B7 
B*0715B7B7B7 [100]b1B7B7 variant, some Bw6 sera negative
B*0716B7B7B7 [50], B60 [50]b2B7Short B7, few B7 sera reactive, similar to B703
B*0717B7B7B7 
B*0718B7B7 
B*0719B7/42B42 [100]b1B42Short B7
B*0720B7/blankB7Short B7, B7 sera negative, B7 + 42 sera reactive
B*0721B7B7 [100]b1B7 
B*0722B7B7 
B*0723B7bd1B7 
B*0724B7B7B7B7 weakly expressed, reactive with B7 + 27 (+40) sera
B*0725B7B7 
B*0726B7B7B7 [100]b1B7Normal B7
B*0727UndefinedNot assignedeNN: B7
B*0728B7B7 
B*0729B7B7 
B*0730B7B7B7B7 variant
B*0731B7/B42B7/B42B7B7x42, short B7
B*0732B7/blankB7B blank
B*0733B7B7 [100]b1B7 
B*0734B7B7 
B*0735B7B7 
B*0736B7B7 [100]b1B7Bw4 positive
B*0737B7B7 
B*0738UndefinedNot assignede 
B*0739B7B7 
B*0740B7B7B7 
B*0741B7B7 
B*0742B7B7 
B*0743B7B7 
B*0744B7B7 
B*0745B7B7 
B*0746B7B7B7 
B*0747B7B7 
B*0748B7B7 
B*0749NNot expressedNullNT 
B*0750UndefinedNTNN: B7
B*0751B7B7 
B*0752B7B7 
B*0753B7B7 
B*0754B7B7 
B*0755B7B7 
B*0756B7B7 
B*0757B7B7B7 
B*0758B7B7B7 
B*0801B8B8B8 [100]a9B8 [99]6518B861Training – B8 
B*0802B8B8bd2B‘0802’1Not assignedeB8 Bw4; ihw13: B8 Bw4 with extra reactions; NN: B8
B*0803B8B8B8 [100]b1Not assignedeB8 Bw4
B*0804B8/blankB8 [51–71], B59 [6–7]3B8 [80], blank [20]b5B81B8Blank Bw6; ihw13: short B8
B*0805B8bd1B8 
B*0806B8B8B8 [100]b1B8 
B*0807B8B8B8 [100]b1B8 
B*0808NNot expressedNullNT 
B*0809B8B8B8 [100]b11B82B8 
B*0810B8B8B8Short B8
B*0811B8B8 [100]b3B8 
B*0812B8bd1B8 
B*0813B8B8 [100]b1B8 
B*0814B8B8 
B*0815B8B8B81B8 
B*0816B8B8B8 
B*0817UndefinedNot assignedeB blank; NN: B8
B*0818B8B8B8 
B*0819NNot expressedNullNT 
B*0820B8B8 
B*0821B8B8 
B*0822B8B8 
B*0823B8B8 
B*0824B8B8 
B*0825B8B8 
B*0826B8B8 
B*0827B8B8 
B*0828B8B8 
B*0829B8B8B8 
B*0830NNot expressedNullNT 
B*0831B8B8 
B*0832B8B8 
B*0833B8B8 
B*1301B13B13B13 [95–99]a4B13 [97]238B139Training – B13 
B*1302B13B13B13 [98–100]a9B13 [99]1307B1317Training – B13 
B*1303B49/B15B13 [100]b1B13B15x21–Bw4; B21 variant with some B15 sera reactive
B*1304B49/B15B15/B21B21 [22–38], B49 [15], B15 [7–17], B15x21 [0–15], B50 [5–11], B63 [0–8], B77 [4–7]2B‘1304’1B13B15x21–Bw4, similar to B*1303; ihw13: new pattern, also B49, B63 and B77 reactivity
B*1306B13B13 
B*1307NNot expressedNullNT 
B*1308B13B13 
B*1309UndefinedNot assignedeBw6pos; NN: B13
B*1310B13B13 [100]b2Not assignedeNN: B13 B15
B*1311B13B13 [100]b1B13 
B*1312B13B13 
B*1313B13B13 B13 
B*1314B13B13 
B*1315B13B13 
B*1316B13B13 
B*1317B13B13 
B*1318B13B13 
B*1319B13B13 
B*1320B13B13 
B*1401B64B64(14)B14 [49–58], B64 [32–43], B65 [2–10]a8B14 [72], B64 [10], B65 [10]1003B6411Training – B14 
B*1402B65B65(14)B65 [50–54], B14 [45–47], B64 [1–3]a9B14 [71], B65 [25], B64 [2]2244B6522Training – B14 
B*1403B14B14cB14 [50], B65 [35]40B14 
B*1404B14B14 [67], B64 [33]b3B14 
B*1405B14B14 [40], blank [60]b5B651B14 
B*1406B14B14B14 [100]b8B14B65
B*1407NNot expressedNull NT 
B*1501B62B62(15)B62 [93–98]a30B62 [96], B15 [2]1906B6264Training – B15 B62 
B*15010102NNot expressedNullNT 
B*1502B75B75(15)B75 [79–86], B15 [8–11], B62 [5–12]16B75 [62], B62 [22], B15 [7]1035B7518Training – B15 B75 
B*1503B72B72(70)B70 [47–61], B72 [31–45]a17B70 [61], B72 [10], B35 [2], B62 [1], blank [11]2569B7225Training – B70 B72 
B*1504B62B62(15)B62 [90], B15 [5], B75 [4]a1B62 [69], B15 [10]29B621B62 
B*1505B62B62(15)B62 [88]1B62 [64], B15 [18]22B623B62 
B*1506B62B62(15)B62 [81]b13B62 
B*1507B62B62(15)B62 [93]2B62 [79]101B622Training – B15 B62 
B*1508B75/B62B75(15)B75 [30–48], B15 [19–35], B62 [6–19], B‘1508’ [11–14]2B62 [20], B15 [18], B75 [18]45B753B15 
B*1509B70B70B70 [53], blank [33]65B712Training – B70 B71 
B*1510B71B71(70)B70 [41–49], B71 [41–47]a15B70 [49], B35 [4], B72 [2], B71 [2], B75 [1], B15 [1], blank [13]1204B717Training – B70 B71 
B*1511B75B75(15)B75 [31–51], B15 [21–38], B46 [6–12], B‘1511’ [0–19]3B62 [27], B75 [21], B46 [15], B15 [15]68B754B15 
B*1512B76B76(15)B76 [76–88], B45 [3–6]5B76 [29], B62 [18], B75 [6], B15 [29]b17B762Training – B15 B76 
B*1513B77B77(15)B77 [46–53], B63 [0–16]2B77 [21], B63 [19], B15 [15], B75 [12], blank [13], B62 [8], B53 [6]116B777Training – B15 B77 
B*1514B76B76(15)B76 [23], B45 [20], B15 [20], B70 [6], B63 [5]1B45 [80], B44 [20]b5B761B62 
B*1515B75/62B62(15)B75 [43–57], B62 [31–42], B15 [8–15]a10B62 [49], B75 [28], B15 [13]138B751B15ihw13: short B75
B*1516B63B63(15)B63 [96–97]a8B63 [80], B57 [3], B15 [3]816B633Training – B15 B63 
B*1517B63B63(15)B63 [92–96]5B63 [88], B15 [3], B57 [1]797B6311Training – B15 B63 
B*1518B71B71(70)B70 [52–64], B71 [28–34]a11B70 [51], blank [34], B71 [3]552B718Training – B70 B71 
B*1519B76B76(15)B76 [29], B15 [19], B45 [11], B62 [8], B75 [7]1B70 [50], B76 [50]b2B76 
B*1520B62B62(15)B62 [73], B15 [18], B75 [5]1B62 [100]b10B621B62ihw13: short B62
B*1521B75B75(15)B75 [80–88], B15 [6–9], B62 [3–10]21B75 [55], B62 [12], B15 [7]132B759Training – B15 B75 
B*1523B70/B5/blankB‘1523’ [17], B5 [14–15], B77 [7–11], B70 [7–9], B15 [5–8]2Blank [50], B70 [17], B51 [17], B53 [8]b12B‘1523’2Not assignedeB5x70–Bw4, B5/53/77 variant; NM5; ihw13: new pattern, short B71-Bw4; NN: B70 B71
B*1524B62B62(15)B62 [45–48], B‘1524’ [23–24], B15 [21–22], B77 [4–6], B63 [2–3]4B62 [44], blank [22]54B628B15B62 Bw4
B*1525B62B62(15)B62 [86–94], B75 [2–10]a10B62 [74], B75 [8], B15 [7]116B621Training – B15 B62ihw13: short B62, short B75
B*1526NNot expressedNullNT 
B*1527B62B62(15)B62 [97]a1B62 [76], B15 [7]76B622Training – B15 B62ihw13: short B62, short B75
B*1528B62B62(15)cB62 [80], B15 [20]b5B62 
B*1529B70B15B70 [54–58], B15 [11–12], B71 [7–10]2Blank [71], B70 [19]21B712B71 
B*1530B62B62(15)cB62 [63–86], B75 [4–13], B15 [12–19]3B62 [64], B15 [17]98B623Training – B15 B62ihw13: short B62, short B75
B*1531B75B75(15)B75 [38], B62 [38]b13B751B75ihw13: short B75
B*1532B62B62(15)B62 [100]b5B62 
B*1533B62B15B62B62
B*1534B62B62(15)cB62 [100]b8B62Normal B62
B*1535B62B62(15)cB62 [86–93], B75 [5–7]a14B62 [79]34B625Training – B15 B62 
B*1536UndefinedB13 [100]b3B15Bw4 positive, NN: B77
B*1537B70B70cB70 [46], B71 [11], B78 [9]2Blank [54], B70 [30]24B71 
B*1538B62B62 [100]b3B62B62 variant, also reactive with B52 sera
B*1539B62B62(15)cB62 [92–98]2B62 [84], B15 [13]b38B623B62 
B*1540B62/blankBlank [61], B70 [10], B62 [8]26B62Short B62
B*1542B15B62Short B15; reactive with some B22 sera
B*1543B15B15fBw4 positive, NN: B62
B*1544B75B75 
B*1545B62B62(15)B62 [92]b13B62 
B*1546UndefinedB72(70)B50 [50], B72 [25]b4Not assignedeNN: B15 B62
B*1547B70/blankBlank [57], B35 [14]b14B72B48, all B15 sera negative
B*1548B62B62(15)B62 [100]b3B62 
B*1549B72B72 
B*1550B62B62 
B*1551B70B70B35 [100]b1B71 
B*1552UndefinedB15Blank [67]b3B71B15
B*1553UndefinedNot assignede 
B*1554B72B70 [50], B72 [50]b2B72 
B*1555B15B15B15fB15 Bw6; NN: B75
B*1556B62B62 
B*1557B62B62 
B*1558B62B62(15)B62 [100]b3B62B15 or B62
B*1560B62B62 
B*1561B72B72 
B*1562UndefinedB62 [67]b3Not assignedeNN: B70 B72
B*1563B62B62 [100]b2B62 
B*1564B71B71 
B*1565B62B62 [100]b2B62 
B*1566B62B62 [100]b1B62 
B*1567B63B63Bw4 positive
B*1568UndefinedB35Not assignedeNN: B70 B72
B*1569B72B72 
B*1570B62B62(15)B621B62ihw13: short B62, short B75
B*1571B62B62(15)B62 [83], B75 [17]b6B62 
B*1572B71B71 
B*1573B62B62(15)B62 [100]b1B62 
B*1574B72B72 
B*1575B62B62 [100]b1B62 
B*1576UndefinedNot assignedeNN: B15
B*1577B62B62 
B*1578B62B15B62 
B*1579NNot expressedNullNT 
B*1580B70B70B71B70
B*1581B62B62 
B*1582B62B62(15)B62B62 + A30/31
B*1583B62B62NN: B15
B*1584B62B62(15)B62 
B*1585B62B62 
B*1586UndefinedNot assignedeNN: B15, B62
B*1587B15B15 
B*1588B75B75 
B*1589B77B77 
B*1590B71B71 
B*1591UndefinedNot assignedeNN: B70, B72, B12
B*1592B62B62 
B*1593B71B71(70)B71 
B*1594NNot expressedNullNT 
B*1595B63B63 
B*1596B62B62(15)B62 
B*1597B62B62 
B*1598B72B72 
B*1599B71B71 
B*9501UndefinedNot assignedeNN: B15, B46
B*9502B62B62(15)B62 
B*9503B70B70B72 
B*9504B62B62 
B*9505B62B62 
B*9506UndefinedNot assignedeNN: B15, B62
B*9507B62B62(15)B62 
B*9508B71B71(70)B71 
B*9509B62B62 
B*9510B62B62 
B*9511NNot expressedNullNT 
B*9512B75B15B75 
B*9513B62B62 
B*9514B70B70B71 
B*9515B70B70 
B*9516B62B62 
B*9517B62B62 
B*9518B62B62 
B*9519B71B71 
B*9520B62B62 
B*9521B75B75 
B*9522B62B62 
B*9523B72B72 
B*9524B71B71 
B*9525B62B62 
B*9526B62B62 
B*9527B72B72 
B*9528B62B62 
B*9529B62B62 
B*9530B62B62 
B*9532B72B72 
B*1801B18B18B18 [97–100]a12B18 [96]1641B1853Training – B18 
B*1802B18B18B18 [90]31B183Training – B18 
B*1803B18B18B18 [83], blank [17]29B181B18 
B*1804B18B18cB18 [84], blank [11]b19B181Not assignedeNN: B18
B*1805B18B18B18 [83]b6B181B18ihw13: short B18, blank
B*1806B18B18B18B18 variant, negative with Bw4 and Bw6 sera
B*1807B18/blankBlank [100]b1B181B18ihw13: short B18, blank, B18 spec sera negative
B*1808B18B18 [100]b1B18 
B*1809B18B18Not assignedeB18, Bw4; NN: B18, B38
B*1810B18B18 
B*1811B18B18 
B*1812B18B18 [50], blank [50]b2B18 
B*1813B18B18 [100]b2B18 
B*1814B18B18 [100]b2B18 
B*1815B18B18 [100]b1B18 
B*1817NNot expressedNullNT 
B*1818B18B18 [100]b4B18 
B*1819B18B18 
B*1820B18B18 
B*1821UndefinedNot assignedeNN: B18
B*1822B18B18 
B*1823NNot expressedNullNT 
B*1824B18B18 
B*1825B18B18 
B*1826B18B18 
B*2701B27B27B27 [100]b12B27 
B*2702B27B27B27 [97]1B27 [87]417B279Training – B27ihw13: short B27
B*2703B27B27B27 [97]1B27 [88]26B275Training – B27 
B*2704B27B27B27 [98]a1B27 [97]31B277B27 
B*2705B27B27B27 [99–100]6B27 [99]1194B2722Training – B27 
B*2706B27B27B27 [97–99]a10B27 [97]29B276B27Previously also named B*2722
B*2707B27B27B27 [100]b49B275B27 
B*2708B2708/B27/B7B2708B2708 [36–58], B7 [19–41], B27 [11–19]3B27 [31], B7 [34], blank [16], B2708 [9]b32B27081B27B7 variant, most B27 sera negative; ihw13: also B73 B7 blank
B*2709B27B27B27 [100]1B27 [100]b15B27 
B*2710B27B27B27 [100]b5B27 
B*2711B27B27B27 [100]b2Not assignedeB27 variant, extra reactivity with B40 sera; NN: B27
B*2712UndefinedB27Blank [78], B60 [9], B27 [4], B61 [4]b23Blank1Not assignedeBlank Bw6; B27 sera negative, B7 + 27 (+40) sera positive; ihw13: blank, B61 B27–Bw6; NN: B27
B*2713B27B27B27 
B*2714B27B27cB27 [100]b14B27 
B*2715B27B27Blank Bw4
B*2716B27B27Short B27, some B40 sera reactive
B*2717B27B27B27Normal B27
B*2718UndefinedBlank [100]b2Not assignedeBw6 positive
B*2719B27B27B27Normal B27
B*2720B27B27B27 
B*2721B27B27 
B*2723UndefinedNot assignedeBlank Bw6, Bw4 negative/weak, only reactive with few B44 + 27 sera
B*2724B27B27 
B*2725B27B27 
B*2726B27B27 
B*2727B27B27 
B*2728B27B27 
B*2729B27B27Not assignedeNN: B27
B*2730B27B27B27 
B*2731B27B27 
B*2732B27B27 
B*2733UndefinedNot assignedeNN: B27, B40, B61
B*2734B27B27NN: B27
B*2735B27B27 
B*2736B27B27 
B*2737B27B27 
B*2738B27B27B27 
B*3501B35B35B35 [97–100]a27B35 [98]2023B3558Training – B35 
B*3502B35B35B35 [94–99]3B35 [72]1013B359Training – B35 
B*3503B35B35B35 [95–100]3B35 [94]1226B3522Training – B35 
B*3504B35B35B35 [100]26B35 
B*3505B35B35B35 [98–99]9B35 [94]231B357Training – B35 
B*3506B35B35B35 [100]b13B35 
B*3507B35B35B35 
B*3508B35B35B35 [95–98]a6B35 [91]345B355Training – B35 
B*3509B35B35B35 [100]b3B35 
B*3510B35B35cB35 [77], B70 [15]b13B351B35ihw13: short B35
B*3511B35B35B35 [88]b16B35 
B*3512B35B35B35 [98–100]a12B35 [78]422B352B35 
B*3513B35B35bB35 
B*3514B35B35B35 [98]a1B35 [79]29B35 
B*3515B35B35Blank [50], B35 [33]b6B35Short B35, B75 CREG sera reactive
B*3516B35B35cB35 [63], B70 [20]2B35 [33], blank [34]41B351B35ihw13: short B35
B*3517B35B35B35 [97–100]9B35 [93]261B352Training – B35 
B*3518B35B35B35 [100]b1B35 
B*3519B35/blankB35B35 [40], B70 [20], B77 [20]b5Blank2B35ihw13: new pattern, blank, very short B35
B*3520B35B35B35 [42], blank [13]23B355B35 
B*3521B35/B78B35 [42], B78 [33], blank [25]b12B781B35ihw13: B35/78 variant
B*3522B35B35 [100]b2B35 
B*3523B35B35cB35 [84–88]4B35 [92]b13B351B35 
B*3524B35B35 [75], B78 [25]b8B35 
B*3525B35B35cB35 [33], blank [67]b3B351B35ihw13: short B35
B*3526B35B35 
B*3527B35B35B35 [100]b2B35 
B*3528B35B35 [50], blank [43]b14B35 
B*3529B35B35B35 [100]b2B35 
B*3530B35B35B35 [100]b7B35Normal B35
B*3531B35Blank [67], B61 [17], B48 [17]b6B351B35ihw13: short B35; reactive with few B40 and B35 sera, Korean
B*3532B35B35B35 [100]b2B35 
B*3533B35B35 
B*3534B35B35 [100]b1B35 
B*3535B35B35B35 
B*3536B35B35 [100]b1B35 
B*3537B35B35 [100]b1B35 
B*3538B35bd1B35 
B*3539B35B35 
B*3540NNot expressedNullNT 
B*3541B35B35B35 [100]b3B35 
B*3542B35B35B35Normal B35
B*3543B35B35B35 [95–97]a3B35 [63], B70 [12]379B352Not assignedePreviously B*1522; NN: B35
B*3544UndefinedB35Not assignedePreviously B*1559
B*3545B35B35 
B*3546B35B35B35 
B*3547B35B35 [100]b1B35 
B*3548B35B35 
B*3549B35B35 [100]b1B35 
B*3550B35B35B35 
B*3551B35B35B35 
B*3552B35B35B35 
B*3553NNot expressedNullNT 
B*3554B35B35 
B*3555B35B35B35 
B*3556B35B35 
B*3557B35B35B35 
B*3558B35B35 
B*3559B35B35 
B*3560B35B35Not assignedeNN: B35
B*3561B35B35B35 
B*3562B35B35 
B*3563UndefinedNot assignedeNN: B40
B*3564B35B35 
B*3565QB35B35Not expected to be expressed
B*3566B35Blank [100]b1B35 
B*3567UndefinedNot assignedeNN: B35
B*3568B35B35 
B*3569B35B35 
B*3570B35B35B35 
B*3571B35B35 
B*3572B35B35 
B*3573B35B35 
B*3574B35B35 
B*3575B35B35 
B*3576B35/22B35/22B22fNN: B56
B*3577B35B35 
B*3701B37B37B37 [98–100]a6B37 [93]1721B3727Training – B37 
B*3702B37/B27B27 [33], blank [33], B37 [17], B47 [17]b6Not assignedeB37x27 or blank; few B37 and few B27 sera reactive; NN: B37
B*3703NNot expressedNullNT 
B*3704B37B37cB37 [50], blank [50]b2B371B37B37 variant, reactive with few B37 and B18 sera
B*3705BlankNot assignedeBlank Bw6, B37, and Bw4 sera negative, Korean; NN: B37
B*3706B37B37 
B*3707UndefinedNot assignede 
B*3708B37B37B37 
B*3709B37B37Not assignedeNN: B37
B*3710B37B37B37 
B*3711UndefinedNot assignedeNN: B37
B*3712B37B37 
B*3713B37B37 
B*3801B38B38(16)B38 [96–100]a14B38 [94], B16 [1], B39 [1]2317B3843Training – B16 B38 
B*3802B38B38(16)B38 [91–99]a15B38 [87], B39 [2], B16 [2]788B3815Training – B16 B38ihw13: different from B*3801
B*3803B38B16Blank [100]b1Not assignedeB16 Bw4, B38, and B39 sera negative; NN: B16 B38
B*3804B38B38 
B*3805B38B38(16)B38Normal B38
B*3806B38B38 
B*3807B38B38 
B*3808B38B38 
B*3809B38B16cB38B16–Bw4, on cell VOA Ter 299
B*3810B38B38 
B*3811B38B38 
B*3812B38B38(16)B38 
B*3813B38B38 
B*3814B38B38 
B*3815B38B38(16)B38 
B*3816B38B38 
B*3901B3901/B39B3901B39 [96–99]a7B39 [95]476B3921Training – B16 B39 
B*39010102LLow B39Low B39 Identical to B*3901 
B*3902B3902/B39B3902B39 [97–99]a7B39 [87]96B395Not assignedeihw13: short B39; NN: B16 B39
B*3903B39B39(16)B39 [89]19B391B39 
B*3904B39B39(16)bB39 
B*3905B39B39cB39 [89–92], B16 [4–7], B38 [1–5]a17B39 [82]245B394B39B39 variant, ST-16; ihw13: B39 and B38 sera positive
B*3906B39B39(16)B39 [96–99]6B39 [94]508B398Training – B16 B39 
B*3907B16Blank [100]b1B16 
B*3908B39B39(16)B39 [86–91], B16 [3–5]4B39 [48], blank [41]57B391Not assignedeihw13: B39 and B38 sera positive; NN: B16
B*3909B39B39(16)B39 [96–99]6B39 [100]b29B392B39 
B*3910B39B39(16)B39 [98]a4B39 [82], blank [16]127B395B39 
B*3911B39B39(16)cB39 [79], blank [14]b29B39 
B*3912B39B39(16)B39 [100]b1B391B39 
B*3913B39B39(16)B39 [40], blank [40]b5Not assignedeNN: B16, B39
B*3914B39B39 [100]b4B39 
B*3915B39B39(16)cB39 [100]b6B391B39 
B*3916B39B39 
B*3917B39B39 [100]b1Not assignedeNN: B39, B16
B*3918B39B39 
B*3919B39B39(16)cBlank [100]b1B391B39 
B*3920B39B39 [73], B16 [16]a1Blank [67], B38 [33]b3B16fNN: B38
B*3922B39bd1B39 
B*3923B39B39(16)Not assignedeNN: B16, B39
B*3924B39B39(16)B39 [97]b30B391B39Normal B39
B*3925NNot expressedNullNT 
B*3926B39B39 
B*3927B39B39(16)B39Normal B39
B*3928B39B39 
B*3929B39B39 
B*3930B39B39 
B*3931B39B39 [100]b2B39 
B*3932B16B16fNN: B39
B*3933B39B39 
B*3934B39B39(16)B39 
B*3935B39B39 [100]b1B39 
B*3936UndefinedNot assignedeNN: B39, B16, B14
B*3937B39B39 
B*3938QB39B39Not expected to be expressed
B*3939B39B39 
B*3940NNot expressedNullNT 
B*3941B39B39(16)B39 
B*3942B39B39 
B*4001B60B60(40)B60 [96–98]a37B60 [93], B40 [4], B61 [2]3854B6048Training – B40 B60 
B*4002B61B61(40)B61 [75–95], B40 [3–19], B60 [2–21]a24B61 [80], B60 [8], B40 [6]1460B6133Training – B40 B61 
B*4003B61B61(40)cB61 [62], B60 [23]31B611B61 
B*4004B61B61(40)cB61 [47], B60 [12]57B613B61 
B*4005B4005/B50B4005B4005 [41–57], B50 [28–36], B21 [5–9]3B50 [34], B4005 [12], blank [23], B61 [7], B70 [4], B21 [4], B60 [4]293B61BN21, B21 variant
B*4006B61B61(40)B61 [87–90], B40 [4], B60 [4–8]a6B61 [75], B60 [5], B40 [5]585B6117Training – B40 B61 
B*4007B60B60(40)cB60 [100]b12B60B‘Fu’
B*4008B61/blankB61 [20–27], B40 [20–30], B‘4008’ [9–10], B48 [2–14]3Blank [71], B61 [12], B40 [9]138B612B61B40x48 variant, only reactive with some B40 + 48 (+7) CREG sera
B*4009B61B61(40)B61 [60], B40 [20]b5B611B61 
B*4010B60B60(40)B60 [75–93], B40 [14–15], B61 [3–8], B48 [2–3]a10B60 [43], B61 [25], B40 [14], blank [11]b28B602B60Short B60, B48 like
B*4011B61B61(40)cB61 [71], B60 [26]b38B612B61 
B*4012B60/B48B48 [28–34], B70 [7–20], B40 [11], B72 [10], B‘4012’ [8], B61 [5]3B48 [37], B60 [26], blank [21], B40 [16]b19Not assignedeB48x70, some reactivity with B40 + 48 and B15 + 70 CREG sera; NN: B48
B*4013UndefinedBlank [100]b1Not assignedeB40 Bw4; NN: B61 B40
B*4014B60B60(40)B60 [100]b3B40fNN: B60
B*4015UndefinedNot assignedeNN: B41
B*4016B61B61(40)B61 [58], B60 [25], B40 [17]b12Not assignedeNN: B40, B41
B*4018B61B61 [100]b1B61 
B*4019B61B‘4019’1Not assignedeB40Bw4, B*4002 with Bw4 epitope; ihw13: new pattern short B61 Bw4 positive; NN: B61, B40
B*4020B61B61(40)cB61 [77], B60 [8], B40 [8]b13B611B61 
B*4021B40/B15Not assignedeB40x15, reactive with B40 + 48, B15 + 57 sera, not with B40 + 13 sera; NN: B15, B48
B*4022NNot expressedNullNT 
B*4023B40B40fNN: B60
B*4024B61B61 
B*4025B40B60Short B40, few B40 sera reactive
B*4026B21B21B40fNN: B61
B*4027B61B61(40)B61 [68], B60 [26]b19B61Normal B61
B*4028UndefinedNot assignedeNN: B40, B61
B*4029B61B61(40)B611B61 
B*4030B60B601B60ihw13: B61 with few B60 sera pos
B*4031B60B60(40)bd1B60Normal B60
B*4032B40B60 [50], B61 [50]b2Not assignedeNN: B40, B41
B*4033B60B60 
B*4034B60B60(40)B60 
B*4035B61B61(40)B61Short B40, B60 sera negative
B*4036B60B60 
B*4037B61B61 [100]b1B61 
B*4038B60B60 
B*4039B61/B41B41B61 
B*4040B61B61 [100]b1B61 
B*4042B60B60 
B*4043B60B60 
B*4044B61B61 
B*4045B60B60 
B*4046B60B60 
B*4047B40B40Not assignedeB40 Bw4; short B60, Bw4pos: NN: B40, B60
B*4048B60B60(40)B60 
B*4049B60B60 
B*4050B61B61(40)B61 
B*4051UndefinedNot assignedeNN: B40
B*4052B60B60(40)B60 
B*4053B61B61(40)B61 
B*4054B60B60(40)B60 
B*4055B60B60 
B*4056B61B61(40)B61 
B*4057B61B61 
B*4058B40B40 
B*4059B40B40fNN: B60
B*4060UndefinedNot assignedeNN: B60, B40
B*4061B60B60 
B*4062B60B60 
B*4063B60B60 
B*4064B61B40B61 
B*4065B60B60 
B*4066B60B60 
B*4067B60B60 
B*4068UndefinedNot assignedeNN: B40, B61
B*4069B60B60 
B*4070B61B61(40)B61 
B*4071B61B61 
B*4072B60B60 
B*4073B60B60 
B*4074B60B60 
B*4075B61B61 
B*4076B60B60 
B*4077B60B60 
B*4101B41B41B41 [91–95]a7B41 [87]543B4114Training – B41 
B*4102B41B41B41 [91–95]9B41 [87]478B4116Training – B41 
B*4103B41B41B41 [92]b13B41 
B*4104B41B41 
B*4105B41B41Short B41, Bw6 sera negative
B*4106B41B41 
B*4107B41B41 
B*4108B41B41 
B*4201B42B42B42 [89–97]a12B42 [93], B55 [1], B7 [1]1015B429Training – B42 
B*4202B42B42B42 [87–96], B67 [0–12]6B42 [95]80B422Training – B42 
B*4204B42B42 
B*4205B42Blank [100]b1B42 
B*4206B42B42 
B*4207UndefinedNot assignedeNN: B42, B8
B*4208B42B42 
B*4209B42B42 
B*4402B44B44(12)B44 [99–100]B44 [98]6959B4455Training – B12 B44 
B*44020102SSee commentSolubleIdentical to B*4402Secreted molecule only (reference: 62)
B*4403B44B44(12)B44 [97–100]a30B44 [94]2854B4465Training – B12 B44 
B*4404B44B44(12)B44 [65]42B447B44ihw13: short B44
B*4405B44B44(12)B44 [92]130B441B44 
B*4406B44B44(12)B44 [46], blank [31]b13B447Not assignedeShort B44 or blank; ihw13: blank, short B44; NN: B44, B12
B*4407B44B44(12)B44 [100]b3B44 
B*4408B44B44(12)B44 [100]b3B443B44Short B44; also reactive with B62 + 63 + 57 sera, in Welsh, but very rare; ihw13: new pattern
B*4409B45B45(12)cB45 [92]b12B451B12B44Bw6, will be typed as B45 or B12; most B44- and B45-specific sera negative
B*4410B44B44(12)cB44 [70]37B12fNN: B44
B*4411B44B44 [100]b2B44 
B*4412B44B44(12)B44 
B*4413B44B44(12)B44 
B*4414B44B44(12)B44Short B44
B*4415B12B12B45B45 Bw4, will be typed as B44 or B12
B*4416B47/B44B47B47 [52], B44 [12]1B44B44x47, reactive with most B47 and few B44/12 sera
B*4417B44B44(12)B44 [100]b1B44 
B*4418B44B44 [100]b1B12fNN: B49
B*4419NNot expressedNullNT 
B*4420B44B44 [100]b1B44 
B*4421B44B44 [100]b1B442B44ihw13: blank or very short B44
B*4422B44B44 [100]b1B44 
B*4423NNot expressedNullBlank1NT 
B*4424B44B44 
B*4425B44B44 [100]b1B44 
B*4426B44B44 
B*4427B44B44(12)B44 [100]b30B44Short B44
B*4428B44B44 
B*4429B44B44(12)cB44 [100]b2B44Normal B44
B*4430B44B44 
B*4431B44B44(12)Not assignedeAlmost normal B44; NN: B60, B40, B12
B*4432B44B44(12)B44Short B44
B*4433B44B44 
B*4434B44B44 
B*4435B44B44Normal B44
B*4436B44B44 
B*4437B44bd2B44 
B*4438B44B44 
B*4439B44B44 
B*4440B44B44(12)B44 
B*4441B44B44 
B*4442UndefinedB21B44 
B*4443B44B44(12)B44 
B*4444B44B44 
B*4445B44B44 
B*4446B12B12 
B*4447B44B44 
B*4448B44B44 
B*4449B44B44 
B*4450B44B44 
B*4451B44B44 
B*4452NNot expressedNullNT 
B*4453B44B44(12)B44 
B*4454B44B44(12)B44 
B*4501B45B45(12)B45 [96–99]7B45 [93], B12 [1], B44 [1], B50 [1]2307B4516Training – B12 B45 
B*4502B45B45 [100]b3B45 
B*4503B45B45 
B*4504B21B21fNN: B50
B*4505B45B45 
B*4506B45B45 [100]b1B12fNN: B45
B*4507B45 B45 
B*4601B46B46B46 [91–97]a17B46 [58], blank [27], B62 [1], B35 [1]1487B4630Training – B46 
B*4602B46B46B46B46 variant, negative with B46 + 75 sera
B*4603B46B46B46 
B*4604B46B46B46 
B*4605B46B46B46 
B*4606UndefinedNot assignedeNN: B46, B81
B*4607NNot expressedNullNT 
B*4608B46B46 
B*4609B46B46 
B*4610B46B46 
B*4611B22B22 
B*4701B47B47B47 [90–96]3B47 [50], B27 [5], blank [32]311B4712Training – B47 
B*4702B47B47B47 [40], blank [40], B60 [20]b5B611Not assignedeB47 Bw6, B47 + 13 + 27 sera negative, B40 + 13 + 47 sera positive; NN: B47
B*4703B47B47B47 [70–77], B60 [4–9], B61 [7–8], B40 [6–7]2Blank [33], B47 [17], B13 [17], B40 [17], B61 [17]b6B471B47B47 Bw4, B47 + 13 sera negative, B40 + 13 sera positive
B*4704UndefinedNot assignedeNN: B47
B*4705B17B47 
B*4801B48B48B48 [90–100]a26B48 [78], B60 [6], B61 [2], B40 [2]610B4811Training – B48 
B*4802B48/B70B48Blank [44], B35 [16], B70 [13], B48 [3]39B712Not assignedeB71 like; ihw13: pattern identical to B*1510; NN: B35
B*4803B48B48cB48 [97]a1B48 [66], B60 [13]32B481B48 
B*4804B48B48B48 [50], B40 [25]b4B48Normal B48
B*4805B48B48Not assignedeNN: B48, B7
B*4806UndefinedNot assignedeNN: B48
B*4807B48B48B60 [42], B48 [33], B61 [8]b12B482B48 
B*4808UndefinedNot assignedeNN: B7, B48
B*4809B48B48B48 
B*4810B48B48B48 
B*4811B48B48 
B*4812B48B48 
B*4813UndefinedNot assignedeNN: B48, B61
B*4814B48B48 
B*4815B48B48 
B*4816B48B48 
B*4817UndefinedB48/40Not assignedeNN: B48
B*4818B48B48 
B*4901B49B49(21)B49 [94–98]a6B49 [94], B50 [1], B21 [1]3002B4922Training – B21 B49 
B*4902B49B49(21)B49 [100]b6B49Normal B49
B*4903B49B491Not assignedeShort B49; NN: B49, B21
B*4904B49B49 
B*4905B49B49(21)B49 
B*5001B50B50(21)B50 [92–97]a12B50 [85], B21 [3], B49 [2], B45 [1]1700B5020Training – B21 B50 
B*5002B45B45(12)B45 [87–91], B50 [7], B44 [5]a2B45 [96]79B453Training B12 B45 
B*5004B50B50(21)B50 [67]b3B50 
B*5101B51B51(5)B51 [96–99]40B51 [96], B5 [2], B52 [1]1899B5188Training – B5 B51 
B*5102B5102/B51B5102B51 [38–57], B5102 [21–33], B53 [8–16], B5 [4–7], B52 [3–7]11B51 [73], B53 [11], B52 [6], B5102 [3], B5 [3]218B51025B51ihw13: short B51 with some B35 + 53 sera reactive
B*5103B5103/B51B5103B51 [100]b3B51 
B*5104B51B51(5)cB51 [75], B52 [12], B5 [12]b8B511B51 
B*5105B51B51(5)B51 [45], B53 [33], B5 [3], B52 [3]1B51 [48], B53 [24], B52 [16]25B513B51ihw13: B5102, short B51 with some B35 + 53 sera reactive
B*5106B51B51(5)B51 [82–88], B53 [1–4], B52 [0–4], B5102 [0–3]a5B51 [64], B53 [12], B52 [7]42B515B51B5, most B51 sera negative; ihw13: short B51, distinct pattern
B*5107B51B51(5)B51 [78], B52 [9]68B513Training – B5 B51ihw13: short B51, distinct pattern
B*5108B51B51(5)B51 [96–99]a3B51 [77], B53 [4]154B514Training – B5 B51 
B*5109B51B51(5)B51 [86]43Training – B5 B51 
B*5110B51Blank [100]b2B511B51ihw13: B5102, short B51 with some B35 + 53 sera reactive
B*5111NNot expressedNullNT 
B*5112B51/blankB51B ‘blank’, possibly not expressed
B*5113B51B51 [95–98]a2B51 [100]b7B51 
B*5114B51B51(5)cB51 [88], B5 [12]b17B511B51 
B*5115UndefinedNot assignedeNN: B59
B*5116B51B5B51 [100]b1B51 
B*5117B51B51(5)B51 
B*5118B51B51(5)B51 
B*5119B51B51 
B*5120B51B51 
B*5121B51B51 [100]b1B51 
B*5122B51B51 [100]b2B51 
B*5123B51d2B51 
B*5124B51B51(5)B511B51 
B*5126B51B51 
B*5127NNot expressedNullNT 
B*5128B51B51(5)B511B51 
B*5129B51B51(5)B51 [100]b1B51 
B*5130B51B51 
B*5131B51B51(5)d1B51 
B*5132B51B51 
B*5133B51B51 
B*5134B51B51 
B*5135B51B51(5)B51 
B*5136B51B51 
B*5137B51B51 
B*5138B51B51 
B*5139B51B51 
B*5140B51B51 
B*5141NNot expressedNullNT 
B*5142UndefinedB44(12)Not assignedeNN: B44, B12, B53
B*5143B51B51(5)B51 
B*5144NNot expressedNullNT 
B*5145UndefinedNot assignedeNN: B5, B51
B*5146B51B51(5)B51 
B*5147B51B51 
B*5148B51B51 
B*5149B51B51 
B*5201B52B52(5)B52 [93–95]13B52 [82], B51 [7], B5 [2], B53 [1]2823B5232Training – B5 B52 
B*5202B52B52 [100]b2B52 B15 
B*5203B52B52 [100]b1B52 
B*5204B52B52(5)B52 [76], B5 [11]1B52Normal B52
B*5205B52B52 
B*5206B52B52 
B*5207B52B52(5)B52 
B*5208B52B52(5)B52 
B*5209B52B52 
B*5210B52B52 
B*5211B52B52 
B*5301B53B53B53 [91–94]a25B53 [86], B35 [5], B51 [1]3054B5320Training – B53 
B*5302B53B53 [83]b6B53 
B*5303B53/B35B35 [100]b2Not assignedeNN: B35, B53
B*5304B53B53 [100]b2B53Long B53, some B5 sera reactive
B*5305B53B53 [100]b3B53 
B*5306B53/B51B511B53B53x51, long B53, extra reactivity with some B51 sera
B*5307B53B53Not assignedeB53x37, reactive with some B37 CREG sera; NN: B51, B5
B*5308B53B53 
B*5309B53B53 
B*5310B53B53 [100]b1B53 
B*5311B53B53B53 
B*5312B53B53 
B*5313B53B53 
B*5401B54B54(22)B54 [88–94]a8B54 [67], B55 [10], B22 [3], B56 [2], blank [9]631B5420Training – B22 B54 
B*5402B54B54(22)B54 
B*5403B22B54 B56 
B*5404B54B54 
B*5405NNot expressedNullNT 
B*5406UndefinedNot assignedeNN: B22
B*5407B54B54 
B*5408NNot expressedNullNT 
B*5409UndefinedNot assignedeNN: B54, B22
B*5410B54B54 
B*5411B54B54(22)B54 
B*5412UndefinedNot assignedeNN: B54, B22
B*5413B54B54 
B*5501B55B55(22)B55 [89–97]4B55 [92], B22 [5]453B5521Training – B22 B55 
B*5502B55B55(22)B55 [89–96]a6B55 [84], B54 [3], B22 [2]309B5511Training – B22 B55 
B*5503B55B55(22)cB55 [100]b1B55B55x67, some Bw6 sera negative
B*5504B55B55(22)B55 [80], B56 [7], B22 [7]b15B22 
B*5505B55B22B22 [100]b1B55 
B*5507B54B54(22)B55 [25], B54 [25], B56 [25], blank [25]b4B22fNN: B54
B*5508B56B56(22)B562B56 
B*5509B22B22B55Short B22, B7 CREG sera positive, negative with B55 and B56 sera
B*5510B55B55(22)B55 [100]b1B22 
B*5511B55B55 
B*5512B55B22B55 
B*5513B55B55 [100]b1B55B55v
B*5514UndefinedNot assignedeNN: B22, B55
B*5515B55B55(22)B55 
B*5516B55B22B55 
B*5517B55B55 
B*5518UndefinedNot assignede 
B*5519B55B55 
B*5520B22B22fNN: B55
B*5521B55B55 
B*5522B22B55(22)B22fNN: B56
B*5523B55B55 [100]b1B55 
B*5524B55B55 
B*5525B55B55 
B*5526B55B55 
B*5527B55B55 
B*5601B56B56(22)B56 [94–96]5B56 [72], B22 [5], B55 [3], blank [8]671B5623Training – B22 B56 
B*5602B56B56(22)B56 [63], B55 [12], blank [25]b8B566Training – B22 B56 
B*5603B22/15B22B56 [65], B22 [6], blank [12]b17B561Not assignedeB22 variant, B55, B56 sera negative, B15 + 46 + 70 sera reactive; in Asians
B*5604B56B56(22)B56 [88–93], B22 [1–5]a4B56 [82], B54 [4], B22 [4], blank [11]b28B561B56Short B56s, some B56 and B22 sera negative
B*5605B56B56(22)Blank [100]b1B564B22Short B56
B*5606B78B78B22B78 variant, some B35 and B15 CREG sera positive, all B22 sera negative
B*5607B56B56(22)B561Not assignedeB56 Bw4, some B7 sera positive; ihw13: B56 Bw4; NN: B56, B22
B*5608B56B56 
B*5609B56B56 
B*5610B55B55(22)B55Short B22, reactive with B54 + 55 sera, negative with B55 + 7 sera
B*5611B56B56(22)B56Short B56
B*5612B22B55(22)B22 
B*5613B56B56(22)B56 
B*5614B56B56 
B*5615B56B56(22)B56 
B*5616B56B56 
B*5617B56Blank [100]b1B56 
B*5618UndefinedNot assignedeNN: B22
B*5619NNot expressedNullNT 
B*5620B56B56(22)B56 
B*5701B57B57(17)B57 [87–98], B58 [1–7], B17 [1–6]a12B57 [92], B17 [5], B58 [2]3670B5728Training – B17 B57 
B*5702B57B57(17)B57 [95–96]a8B57 [78], B17 [8]65B574Training – B17 B57ihw13: short B57
B*5703B57B57(17)B57 [96–98]a5B57 [85], B17 [6], B58 [6]412B577Training – B17 B57 
B*5704B57B57(17)B57 [67], B17 [7]32B571B57ihw13: short B57
B*5705B57B57 [100]b3B57 
B*5706B57B57 
B*5707B57B57 
B*5708B57B57(17)B57Bw4 sera negative, only strongly reactive with B15 + 57 sera
B*5709B57B57 
B*5710B57B57 
B*5711B57B57 
B*5712B57B57 [100]b1B57 
B*5713B57B57 
B*5801B58B58(17)B58 [90–100]a25B58 [79], B57 [8], B17 [4]2096B5828Training – B17 B58 
B*5802B58B58(17)B58 [82–93]a2B58 [72], B57 [12], B17 [3]837B5810Training – B17 B58 
B*5804B58B58 [100]b1B58 
B*5805B58B58 
B*5806B58B58 [100]b1B58 
B*5807B58B58 
B*5808B17/B5B17B5B17 and some B5 sera reactive; NN: B17
B*5809B17B58B57
B*5810NNot expressedNullNT 
B*5811B58B58 
B*5812B58B58 
B*5813B58B58 
B*5814B58B58 
B*5815B58B58 
B*5901B59B59B59 [92–95]a9B59 [45], blank [41]123B596Training – B59 
B*5902B59B59B59 
B*6701B67B67B67 [86–90], B39 [5–11]a6B39 [43], B67 [32], B55 [8], blank [11]81B675Training – B67ihw13: pattern included in B22
B*6702UndefinedB39 [100]b1Not assignedeNN: B67
B*7301B73B73B73 [81–87]4Blank [69], B73 [22]106B733Training – B73ihw13: pattern similar to B2708
B*7801B78B78B78 [83–90], B35 [1–9], B51 [1–6]5B78 [41], B35 [15], B51 [10], B70 [4], blank [19]210B781Training – B78 
B*7802B78B78B78 [25], B35 [25], B51 [25]b4B78 
B*7803B78B78 
B*7804B35B35 [100]b5Not assignedeNN B35
B*7805UndefinedNot assignedeNN B52
B*8101B81B81B81 [81–90], B7 [10–18], B48 [0–3]a12B7 [76], B81 [8]657B817Training – B81 
B*8102B81B81B81 [89–90], B7 [10], B48 [0–3], B60 [2–3]a2B81 
B*8201B82B82B‘8201’ [28], B22 [9]1Blank [68], B45 [4], B70 [4], B‘82’ [3], B65 [3]146B‘82’4B56B22x45, reactive with some B45 and B22 sera; ihw13: pattern almost included in B55
B*8202B82B82 [23], B81 [19], B‘8201’ [11], B56 [5], B22 [3], B42 [3]a1B45 [33], blank [67]b3B‘82’1B56 
B*8301UndefinedB45 [100]b1Not assignede 
Table 3.  HLA-C alleles and their serologic designationsg
HLA alleleExpert assignedWHO assignedInternational Cell Exchange, UCLANMDPIHWS13 dataNNComments
Assigned type [%]Cells testedAssigned type [%]Cells testedAssignmentCells testedAssigned type >0.55
  • NT, not tested; NN, neural network; HLA, human leukocyte antigen; WHO, World Health Organization; NMDP, National Marrow Donor Program.

  • a

    Updated International Cell Exchange, UCLA.

  • b

    Updated NMDP data. In some cases, the information reported in previous dictionaries has changed. Cells have been excluded from this study in some cases because their HLA typing has changed.

  • c

    WHO assignment based on dictionary data.

  • d

    Not assigned; see comment column for predictions >0.20.

  • e

    The allele has been identified but serology not informative.

  • f

    If a primary specificity is provided by the NN, other specificities >0.4 are shown in the comments column.

  • g 
Cw*0102Cw1Cw1Cw1 [55–75]a76Cw1 [92]260Cw1104Training – Cw1 
Cw*0103Cw1Cw1Cw1 [100]b1Cw1 
Cw*0104Cw1Cw1 
Cw*0105Cw1Cw1 
Cw*0106Cw1Cw1 
Cw*0107Cw1/blankCw1 [100]b1Cw1Cw blank, the HLA club cell exchange: nine laboratories performing serology
Cw*0108Cw1Cw1 
Cw*0109Cw1Cw1Cw1Short Cw1
Cw*0110Cw1Cw1 
Cw*0111Cw1Cw1 
Cw*0112Cw1Cw1 
Cw*0113Cw1Cw1 
Cw*0114Cw1Cw1 
Cw*0115Cw1Cw1 
Cw*0116Cw1Cw1 
Cw*0117Cw1Cw1 
Cw*0118Cw1Cw1 
Cw*0119Cw1Cw1 
Cw*0202Cw2Cw2Cw2 [62–76]a27Cw2 [91]382Cw267Training – Cw2 
Cw*0203Cw2Cw2 [100]b1Cw2 
Cw*0204Cw2Cw2 
Cw*0205Cw2Cw2 
Cw*0206Cw2Cw2 
Cw*0207Cw2Cw2 
Cw*0208Cw2Cw2Cw2 
Cw*0209Cw2Cw2 
Cw*0210Cw2Cw2Cw2 [75]b4 Cw2 
Cw*0211Cw2Cw2 
Cw*0212Cw2Cw2 
Cw*0213Cw2Cw2 
Cw*0214Cw2Cw2 
Cw*0215Cw2Cw2 
Cw*0216Cw2Cw2 
Cw*0217Cw2Cw2 
Cw*0218Cw2Cw2 
Cw*0302Cw10Cw10(w3)Cw3 [45–67], Cw10 [6–13]a13Cw3 [69], Cw10 [5]41Cw1011Cw10 
Cw*0303Cw9Cw9(w3)Cw3 [55–68], Cw9 [8–15]a38Cw3 [80], Cw9 [6]446Cw975Training – Cw3 Cw9 
Cw*0304Cw10Cw10(w3)Cw3 [52–69], Cw9 [0–11], Cw10 [3–12]a62Cw3 [92], Cw10 [3], Cw9 [1]603Cw1051Training – Cw3 Cw10 
Cw*0305Cw3Cw3 [48], Cw10 [7]a1Cw3 [83], blank [17]b12Cw10 
Cw*0306Cw10Cw10(w3)cCw3 [52], Cw10 [6]1Cw3 [75], blank [25]b16Cw101Cw10ihw13: short pattern
Cw*0307Cw3Cw3Cw3 [100]b1Cw10 
Cw*0308Cw10Cw10 
Cw*0309Cw10Cw3cCw3 [44–59], Cw10 [3–6]3Cw3 [100]b1Cw10 
Cw*0310Cw3Cw3Cw3 [100]b1Cw10 
Cw*0311Cw9Cw3Cw9 
Cw*0312Cw9Cw9 
Cw*0313Cw9Cw9 
Cw*0314Cw10Cw10 
Cw*0315UndefinedNot assigneddNN: Cw3, Cw10
Cw*0316BlankCw3Cw3, w9, w10 sera negative; NN: Cw10
Cw*0317Cw10 Cw10 
Cw*0318Cw9Cw3 [100]b1 Cw9 
Cw*0319Cw3Cw3Cw10 
Cw*0320NNot expressedNullNT 
Cw*0321Cw9Cw9 
Cw*0322QUndefinedCw9Not expected to be expressed
Cw*0323Cw10Cw10 
Cw*0324Cw10Cw3Cw10 
Cw*0325Cw10Cw10 
Cw*0326Cw10Cw10(w3)Cw10 
Cw*0327Cw10Cw10 
Cw*0328Cw10Cw10(w3)Cw10 
Cw*0329Cw10Cw10 
Cw*0330Cw9Cw9 
Cw*0331Cw9Cw9 
Cw*0332Cw10Cw10 
Cw*0333Cw10Cw10 
Cw*0334Cw10Cw10 
Cw*0335Cw10Cw10 
Cw*0336Cw10Cw10 
Cw*0337Cw10Cw10 
Cw*0338Cw10Cw10 
Cw*0339Cw9Cw3Cw9 
Cw*0340Cw10Cw3Cw10 
Cw*0341Cw10Cw10 
Cw*0401Cw4Cw4Cw4 [54–76]a107Cw4 [98]736Cw4114Training – Cw4 
Cw*0403Cw4/Cw6Cw4 [16–33], Cw6 [7–26], C‘403’ [3–8]a35Blank [100]b7Cw411Not assigneddNN: Cw4; Cw4/6 variant; ihw13: Cw6 or blank, only Cw4 + 6 sera reactive
Cw*0404Cw4Cw4 [75], blank [25]b4Blank1Cw4 
Cw*0405Cw4Cw4 [100]b2Cw4 
Cw*0406Cw4/Cw6Cw6 [27–33], Cw4 [20–25], C‘403’ [2–3]a4Not assigneddNN: Cw4
Cw*0407Cw4Cw4cCw4 [100]b1Cw41Cw4 
Cw*0408Cw4be1Cw4 
Cw*0409NNot expressedNull1Blank [100]b2NT 
Cw*0410Cw4Cw4Cw4 [100]b1Cw4Normal Cw4
Cw*0411UndefinedNot assigneddNN: Cw4
Cw*0412Cw4Cw4 
Cw*0413Cw4Cw4 
Cw*0414Cw4Cw4 
Cw*0415Cw4Cw4 
Cw*0416Cw4Cw4 
Cw*0417Cw4Cw4 
Cw*0418Cw4Cw4 
Cw*0419Cw4Cw4 
Cw*0420Cw4Cw4Cw4 
Cw*0421Cw4Cw4 
Cw*0423Cw4Cw4 
Cw*0424Cw4Cw4 
Cw*0425Cw4Cw4 
Cw*0426Cw4Cw4 
Cw*0427Cw4Cw4 
Cw*0501Cw5Cw5Cw5 [50–63]a13Cw5 [83], blank [15]579Cw569Training – Cw5 
Cw*0502Cw5Cw5Cw5 [100]b2Cw5 
Cw*0503Cw5Cw5 
Cw*0504Cw5Cw5 
Cw*0505Cw5Blank [100]b1Cw5 
Cw*0506Cw5Cw5 
Cw*0507NNot expressedNullNT 
Cw*0508Cw5Cw5 
Cw*0509Cw5Cw5 [100]b1Cw5 
Cw*0510Cw5Cw5 
Cw*0511Cw5Cw5 
Cw*0512Cw5Cw5 
Cw*0513Cw5Cw5 
Cw*0514Cw5Cw5 
Cw*0515Cw5Cw5 
Cw*0516Cw5Cw5 
Cw*0517Cw5Cw5 
Cw*0602Cw6Cw6Cw6 [51–71]a44Cw6 [74], Cw4 [1], blank [12]665Cw6104Training – Cw6 
Cw*0603Cw6Cw6 [100]b1Cw6 
Cw*0604Cw6Cw6 [100]b2Cw6 
Cw*0605Cw6Cw6Cw6 
Cw*0606Cw6Cw6 
Cw*0607Cw6Blank [100]b1Cw6 
Cw*0608Cw6Cw6 
Cw*0609Cw6Cw6 
Cw*0610Cw6Cw6 
Cw*0611UndefinedNot assigneddNN: Cw6
Cw*0612Cw6Cw6 
Cw*0613Cw6Cw6 
Cw*0614Cw6Cw6 
Cw*0615Cw6Cw6 
Cw*0616NNot expressedNullNT 
Cw*0701Cw7Cw7Cw7 [52–73]a36Cw7 [74], blank [20]304Cw7129Training – Cw7 
Cw*0702Cw7Cw7Cw7 [51–73]a110Cw7 [68], blank [14]976Cw7144Training – Cw7 
Cw*0703Cw7bCw7 
Cw*0704Cw7Cw7Cw7 [59–72]14Cw7 [64], blank [24]54Cw730Cw7 
Cw*0705Cw7Cw7cCw72Cw7 
Cw*0706Cw7Cw7Cw7 [62–76]4Cw7 [67], blank [33]b3Cw7 
Cw*0707Cw7Blank [100]b1Cw7 
Cw*0708Cw7Cw7 [100]b1Cw7 
Cw*0709Cw7Cw7 [100]b1Cw7 
Cw*0710Cw7Cw7 [100]b1Cw7 
Cw*0711Cw7Cw7 
Cw*0712Cw7Cw7Cw7 
Cw*0713Cw7Cw7 
Cw*0714Cw7Cw7Cw7 
Cw*0715Cw7Cw7 
Cw*0716Cw7Cw7Blank [100]b1Cw7 
Cw*0717Cw7Cw7 [61%] allele typed outside primary cell range1Cw7 
Cw*0718Cw7Cw7 [73]a1Cw7 [67], blank [33]b3Cw7 
Cw*0719Cw7Cw7 
Cw*0720Cw7Cw7 
Cw*0721Cw7Cw7 
Cw*0722Cw7Cw7 
Cw*0723Cw7Cw7 
Cw*0724Cw7Cw7 
Cw*0725Cw7Cw7 
Cw*0726Cw7Cw7 
Cw*0727Cw7be1Cw7 
Cw*0728Cw7Cw7 
Cw*0729Cw7Cw7 
Cw*0730Cw7Cw7Cw7 
Cw*0731Cw7Cw7 
Cw*0732NNot expressedNullNT 
Cw*0733NNot expressedNullNT 
Cw*0734Cw7Cw7 
Cw*0735Cw7Cw7 
Cw*0736Cw7Cw7Cw7 
Cw*0737Cw7Cw7Cw7 
Cw*0738Cw7Cw7Cw7 
Cw*0739Cw7Cw7 
Cw*0740Cw7Cw7Cw7 
Cw*0741UndefinedCw8 
Cw*0742Cw7Cw7 
Cw*0743Cw7Cw7 
Cw*0744Cw7Cw7Cw7 
Cw*0745Cw7Cw7Cw7 
Cw*0746Cw7Cw7 
Cw*0747Cw7Cw7 
Cw*0748Cw7Cw7 
Cw*0749Cw7Cw7Cw7 
Cw*0801Cw8Cw8Cw8 [40–66]a62Cw8 [41], blank [34]31Cw840Cw8ihw13: pattern different from Cw*0802
Cw*0802Cw8Cw8Cw8 [55–66]a21Cw8 [67], blank [29]234Cw830Training – Cw8 
Cw*0803Cw8Cw8Cw8 [8–16]a4Blank [100]b3Blank2Cw8 
Cw*0804Cw8Cw8cCw8 [43–57]a4Cw8 [100]b2Cw8 
Cw*0805Cw8Cw8 
Cw*0806Cw8Cw8 
Cw*0807Cw8Cw8 
Cw*0808Cw8Cw8 
Cw*0809Cw8Not assigneddNN: Cw8, Cw7
Cw*0810UndefinedCw5 
Cw*0811UndefinedNot assigneddNN: Cw8, Cw7
Cw*0812Cw8Cw8 
Cw*0813Cw8Cw8 
Cw*0814Cw8Cw8 
Cw*1202UndefinedBlank, no Cw antigen reported by more than 5% of the laboratories11aBlank [94]85Blank27Not assigneddihw13: reactive with broad Cw reagents
Cw*1203UndefinedBlank30aBlank [59], Cw7 [4]238Blank75Not assigneddihw13: reactive with broad Cw reagents
Cw*1204BlankBlank4aBlank [100]b3Cw6 
Cw*1205UndefinedNot assigneddNN: Cw2, Cw6
Cw*1206UndefinedNot assignedd 
Cw*1207UndefinedNot assigneddNN: Cw6
Cw*1208UndefinedNot assignedd 
Cw*1209UndefinedNot assigneddNN: Cw2, Cw6
Cw*1210UndefinedNot assignedd 
Cw*1211UndefinedNot assignedd 
Cw*1212UndefinedNot assignedd 
Cw*1213UndefinedNot assignedd 
Cw*1214Cw7Cw7 
Cw*1215UndefinedNot assignedd 
Cw*1216UndefinedNot assigneddNN: Cw7
Cw*1217UndefinedNot assignedd 
Cw*1218UndefinedNot assigneddNN: Cw7
Cw*1219UndefinedNot assignedd 
Cw*1220UndefinedNot assignedd 
Cw*1221UndefinedNot assigneddNN: Cw2, Cw5
Cw*1402Cw1/blankBlank, no Cw antigen reported by more than 5% of the laboratories19aBlank [93]93Cw136Cw1ihw13: short Cw1
Cw*1403Cw1/blankBlank, no Cw antigen reported by more than 5% of the laboratories5aBlank [100]b11Cw110Not assigneddihw13: short Cw1; NN: Cw1
Cw*1404UndefinedBlank [100]b1Not assigneddNN: Cw4, Cw1
Cw*1405Cw1Blank [100]b1Cw1 
Cw*1406UndefinedNot assigneddNN: Cw1
Cw*1407NNot expressedNullNT 
Cw*1408Cw1Cw1 
Cw*1502UndefinedBlank31aBlank [90]107Blank56Not assigneddNN: Cw10, Cw3, Cw2
Cw*1503UndefinedBlank [100]b2Not assigneddNN: Cw10, Cw3, Cw2
Cw*1504UndefinedBlank [100]b2Blank2Not assigneddNN: Cw3, Cw2
Cw*1505UndefinedBlanka11aBlank [62], Cw7 [24], Cw2 [10]b29Blank5Not assigneddNN: Cw10, Cw3, Cw2, Cw5
Cw*1506UndefinedBlank [100]b1Not assigneddNN: Cw10, Cw3, Cw2
Cw*1507Cw3Cw3fNN: Cw10
Cw*1508UndefinedNot assigneddNN: Cw10, Cw3, Cw2, Cw5
Cw*1509UndefinedBlank1Blank [100]b8Not assigneddNN: Cw3, Cw2
Cw*1510UndefinedNot assignedd 
Cw*1511UndefinedBlank [100]b1Not assigneddNN: Cw2, Cw3, Cw10
Cw*1512UndefinedNot assigneddNN: Cw3, Cw9, Cw2
Cw*1513UndefinedBlank [100]b1Not assigneddNN: Cw10, Cw3, Cw2
Cw*1514UndefinedNot assignedd 
Cw*1515UndefinedNot assigneddNN: Cw10, Cw3, Cw2
Cw*1516UndefinedNot assigneddNN: Cw10, Cw3
Cw*1517UndefinedNot assigneddNN: Cw10, Cw3, Cw2
Cw*1518UndefinedNot assigneddNN: Cw10, Cw3, Cw2
Cw*1519UndefinedNot assigneddNN: Cw3, Cw2
Cw*1520UndefinedNot assigneddNN: Cw3, Cw2
Cw*1521Cw3Cw3fNN: Cw10
Cw*1601UndefinedCw7 [2–23]a36Blank [94]276Blank57Not assignedd 
Cw*1602UndefinedBlanka3Blank [97]22Blank5Not assigneddNN: Cw2, Cw6
Cw*1604UndefinedBlank [100]b10Blank2Not assigneddNN: Cw1
Cw*1606UndefinedNot assigneddNN: Cw7
Cw*1607UndefinedNot assigneddNN: Cw7
Cw*1608UndefinedNot assignedd 
Cw*1609UndefinedNot assigneddNN: Cw2, Cw6
Cw*1701Cw7/blankC‘17’ [27–43], Cw7 [6–22]a25Blank [82], Cw7 [18]b28Not assignedd 
Cw*1702UndefinedNot assignedd 
Cw*1703Cw7/blankC‘17’ [31–44], Cw7 [10–20]a3Blank [100]b8Not assignedd 
Cw*1704UndefinedNot assignedd 
Cw*1801Cw6/blankCw6 [30–42]a3Cw4 [40], Cw6 [40], Cw7 [20]b5Not assigneddNN: Cw6, Cw4
Cw*1802Cw6/blankCw6 [32–49], Cw4 [2–6]a8Cw6 [100]b1Not assigneddNN: Cw6, Cw4
Cw*1803UndefinedNot assigneddNN: Cw6, Cw4
Table 4.  HLA-DRB1 alleles and their serologic designations
HLA alleleExpert assignedWHO assignedInternational Cell Exchange, UCLANMDPNNComments
Assigned type [%]Cells testedAssigned type [%]Cells testedAssigned type >0.55
  • NT, not tested; NN, neural network; HLA, human leukocyte antigen; WHO, World Health Organization; NMDP, National Marrow Donor Program.

  • a

    Updated International Cell Exchange, UCLA.

  • b

    Updated NMDP data. In some cases, the information reported in previous dictionaries has changed. Cells have been excluded from this study in some cases because their HLA typing has changed.

  • c

    Not assigned; see comment column for predictions >0.20.

  • d

    WHO assignment based on dictionary data.

  • e

    The allele has been identified but serology not informative.

  • f

    If a primary specificity is provided by the NN, other specificities >0.4 are shown in the comments column.

DRB1*0101DR1DR1DR1 [95–100]a21DR1 [97]6317Training – DR1 
DRB1*0102DR1DR1DR1 [86–95]2DR1 [95]2035Training – DR1 
DRB1*0103DR103/DR1DR103DR103 [75–80], DR1 [9–17]a5DR1 [56], DR103 [12], blank [18]1186Training – DR1 DR103 
DRB1*0104DR1DR1DR1 
DRB1*0105DR1DR1 [100]b2DR1 
DRB1*0106DR1DR1 
DRB1*0107DR1DR1DR1 
DRB1*0108DR1DR1 
DRB1*0109DR1DR1DR1 
DRB1*0110DR1DR1 
DRB1*0111DR1DR1 
DRB1*0112DR1DR1 
DRB1*0113DR1DR1Not assignedcNN: DR1
DRB1*0114DR1DR1 
DRB1*0115DR1DR1 
DRB1*0116DR1DR1 
DRB1*0301DR17DR17(3)DR17 [33–70], DR3 [20–50], DR18 [0–11]a36DR17 [64], DR3 [33]9698Training – DR3 DR17 
DRB1*0302DR18DR18(3)DR18 [62–67], DR3 [27–35]10DR18 [66], DR3 [24], DR17 [3]317Training – DR3 DR18 
DRB1*0303DR18DR18(3)DR18 [50], DR17 [50]b4DR18 
DRB1*0304DR17DR17(3)DR17 [50], DR3 [44–50]a3DR3 [57], DR17 [29]b7DR17 
DRB1*0305DR3DR3DR17 
DRB1*0306DR3DR3DR17 
DRB1*0307DR3DR3dDR3 [100]b1DR17 
DRB1*0308DR3DR17 
DRB1*0309DR3DR17 
DRB1*0310DR3DR17(3)dDR3 [100]b1DR17 
DRB1*0311DR3DR17(3)dDR3 [100]b1DR17 
DRB1*0312DR3DR3DR17 
DRB1*0313DR3DR17 
DRB1*0314DR3DR3DR17 
DRB1*0315DR17DR3DR3 [38–40], DR17 [20–25], DR18 [0–10]a2DR17 
DRB1*0316DR3DR17 
DRB1*0317DR3DR17 [100]b1DR3 
DRB1*0318DR3DR17 
DRB1*0319DR3DR17 
DRB1*0320DR3DR17 
DRB1*0321DR3DR17 
DRB1*0322DR3DR17 
DRB1*0323DR3DR3DR17 
DRB1*0324DR3DR17 
DRB1*0325DR3DR17 
DRB1*0326DR3DR17 
DRB1*0327DR3DR18 
DRB1*0328DR3DR17 
DRB1*0329DR3DR18 
DRB1*0330DR3DR17 
DRB1*0331DR3DR17 
DRB1*0332DR3DR17 
DRB1*0333DR3DR17 
DRB1*0335DR3DR18 
DRB1*0401DR4DR4DR4 [100]a13DR4 [98]5118Training – DR4 
DRB1*0402DR4DR4DR4 [84–100]4DR4 [92]1029Training – DR4 
DRB1*0403DR4DR4DR4 [97–100]a9DR4 [92]748Training – DR4 
DRB1*0404DR4DR4DR4 [95–100]a20DR4 [89]2164Training – DR4 
DRB1*0405DR4DR4DR4 [94–100]a13DR4 [91]505Training – DR4 
DRB1*0406DR4DR4DR4 [89–100]3DR4 [89]83DR4 
DRB1*0407DR4DR4DR4 [97–100]a7DR4 [86]846Training – DR4 
DRB1*0408DR4DR4DR4 [100]a1DR4 [86]258DR4 
DRB1*0409DR4DR4DR4 [100]b11DR4 
DRB1*0410DR4DR4DR4 [100]3DR4 [84]29DR4 
DRB1*0411DR4DR4DR4 [94–100]a3DR4 [93]76DR4 
DRB1*0412DR4DR4 [100]b1DR4 
DRB1*0413DR4DR4DR4 [100]b3DR4 
DRB1*0414DR4DR4DR4 [100]b1DR4 
DRB1*0415DR4DR4DR4 [84–100], DR11 [20]a4DR4 [67]b3DR4DR4x11
DRB1*0416DR4DR4DR4 [100]2DR4 [100]b1DR4 
DRB1*0417DR4DR4be1DR4 
DRB1*0418DR4DR4 
DRB1*0419DR4DR4DR4 
DRB1*0420DR4DR4DR4 [100]b1DR4 
DRB1*0421DR4DR4DR4 [100]b1DR4 
DRB1*0422DR4/DR3DR4DR4DR4x3
DRB1*0423DR4DR4DR4 
DRB1*0424DR4DR4DR4 
DRB1*0425DR4DR4DR4Short DR4
DRB1*0426DR4DR4DR4 [100]3DR4 [100]b1DR4 
DRB1*0427DR4DR4 
DRB1*0428DR4DR4DR4 
DRB1*0429DR4DR4DR4 
DRB1*0430DR4DR4 
DRB1*0431DR4DR4DR4 [100]a2be1DR4 
DRB1*0432DR4DR4dDR4 [94–100]a2DR4 
DRB1*0433DR4DR4 [100]b1DR4 
DRB1*0434DR4DR4 
DRB1*0435DR4DR4 [100]b1DR4 
DRB1*0436DR4DR4 
DRB1*0437DR4DR4 
DRB1*0438DR4DR4 
DRB1*0439DR4DR4 
DRB1*0440DR4DR4 
DRB1*0441DR4DR4 
DRB1*0442DR4DR4DR4 
DRB1*0443DR4DR4 
DRB1*0444DR4DR4 
DRB1*0445DR4DR4 
DRB1*0446DR4DR4 
DRB1*0447DR4DR4 
DRB1*0448DR4DR4 
DRB1*0449DR4DR4 
DRB1*0450DR4DR4 
DRB1*0451DR4DR4 
DRB1*0452DR4DR4 
DRB1*0453DR4DR4 
DRB1*0454DR4DR4 
DRB1*0455DR4DR4 
DRB1*0456DR4DR4 
DRB1*0457DR4DR4 
DRB1*0458DR4DR4 
DRB1*0459DR4DR4 
DRB1*0460DR4DR4 
DRB1*0461DR4DR4 
DRB1*0462DR4DR4 
DRB1*0463DR4DR4 
DRB1*0464DR4DR4DR4 
DRB1*0701DR7DR7DR7 [93–100]a43DR7 [99]7390Training – DR7 
DRB1*0703DR7DR7DR7 
DRB1*0704DR7DR7DR7 [100]2DR7 
DRB1*0705DR7DR7 
DRB1*0706DR7DR7 
DRB1*0707DR7DR7 
DRB1*0708DR7DR7 
DRB1*0709DR7DR7DR7 
DRB1*0710NNot expressedNullNT 
DRB1*0711DR7DR7 
DRB1*0712DR7DR7 
DRB1*0713DR7DR7 
DRB1*0714DR7DR7 
DRB1*0801DR8DR8DR8 [91–100]a7DR8 [95]1076Training – DR8 
DRB1*0802DR8DR8DR8 [100]a4DR8 [96]265Training – DR8 
DRB1*0803DR8DR8DR8 [96–100]12DR8 [88], DR12 [3]230Training – DR8 
DRB1*0804DR8DR8DR8 [88–100]a9DR8 [93]186Training – DR8 
DRB1*0805DR8DR8DR8 [83]b6DR8 
DRB1*0806DR8DR8DR8 [96–100]4DR8 [95]b21DR8 
DRB1*0807DR8DR8DR8 [89]1DR8 [100]b3DR8 
DRB1*0808DR8DR8 
DRB1*0809DR8DR8DR8 [100]b2DR8DR8 variant
DRB1*0810DR8DR8DR8 [94–100]a2DR8 [67], DR12 [22]b9DR8 
DRB1*0811DR8DR8DR8 [89–94]a2DR8 [100]b10DR8 
DRB1*0812DR8DR8DR8 
DRB1*0813DR8DR8DR8 
DRB1*0814DR8DR8DR8 [74–78]a2DR8 
DRB1*0815DR8DR8 
DRB1*0816DR8DR8DR8 [85]a1DR8 
DRB1*0817DR8DR8DR8 
DRB1*0818DR8DR8DR8 [100]b2DR8 
DRB1*0819DR8DR8 
DRB1*0820undefinedNot assignedcNN: DR8
DRB1*0821DR8DR8 
DRB1*0822DR8DR8 
DRB1*0823DR8DR8 
DRB1*0824DR8DR8 
DRB1*0825DR8DR8 
DRB1*0826DR8DR8 
DRB1*0827DR8DR8 
DRB1*0828DR8DR8 
DRB1*0829DR8DR8 
DRB1*0830DR8DR8 
DRB1*0831DR8/DR11DR11(5)Not assignedcNN: DR8, DR11
DRB1*0832UndefinedNot assignedcNN: DR8, DR12
DRB1*0901DR9DR9DR9 [89–100]19DR9 [95]1058Training – DR9 
DRB1*0902DR9DR9 
DRB1*0903DR9DR9 
DRB1*0904DR9DR9 
DRB1*0905DR9DR9DR9 
DRB1*0906DR9DR9 
DRB1*1001DR10DR10DR10 [87–100]a14DR10 [90], DR1 [4], blank [2]894Training – DR10 
DRB1*1101DR11DR11(5)DR11 [88–100]a15DR11 [92], DR5 [5]3474Training – DR11 
DRB1*1102DR11DR11(5)DR11 [89–100]6DR11 [89], DR5 [3]430Training – DR11 
DRB1*1103DR11DR11(5)DR11 [84–100]2DR11 [89], DR5 [4]397Training – DR11 
DRB1*1104DR11DR11(5)DR11 [87–100]a13DR11 [87], DR5 [4]2119Training – DR11 
DRB1*1105DR11DR11(5)DR11 [90–100]a2DR11 [100]b3DR11 
DRB1*1106DR11DR11(5)DR5 [79], DR11 [21]b14DR11 
DRB1*1107DR11DR11(5)dDR11 [100]b3Not assignedcDR11x3; NN: DR17, DR3, DR11
DRB1*1108DR11DR11(5)DR11 [91–100]a3be1DR11 
DRB1*1109DR11DR11(5)DR11 [100]1DR11 [75], DR5 [25]b4Training – DR11 
DRB1*1110DR11DR11 [100]b2DR11 
DRB1*1111DR11DR11(5)DR11 [87–90], DR13 [7–8], DR5 [4–5]3DR11 [90], DR5 [10]b10DR11DR11x13
DRB1*1112DR11DR11 [100]b5DR11 
DRB1*1113DR11DR11(5)DR11 [93]a2DR11 [86]b7DR11DR11x14
DRB1*1114DR11DR11(5)DR11 [94–100]a3DR11 [100]b2DR11 
DRB1*1115DR11DR11 [50], DR6 [50]b2DR11 
DRB1*1116DR11/DR13DR11(5)/DR13 (6)dDR11 [100]b1DR11DR11x13; DR11 (70), DR13 (30)
DRB1*1117DR14DR14fNN: DR6
DRB1*1118DR11be1DR11 
DRB1*1119DR11DR11(5)DR11 [100]4be1DR11 
DRB1*1120DR11DR11(5)DR11DR11x13
DRB1*1121DR11DR11(5)DR11 [88–97], DR13 [12]a2DR11 
DRB1*1122UndefinedNot assignedcNN: DR11
DRB1*1123DR11DR11(5)DR11 
DRB1*1124DR11DR11 
DRB1*1125DR11DR11(5)DR11 
DRB1*1126DR11DR11(5)DR11 
DRB1*1127DR11DR11(5)DR11 
DRB1*1128DR11DR11 
DRB1*1129DR11DR11(5)DR11 [100]2DR11 
DRB1*1130DR11DR11 
DRB1*1131DR11DR11 
DRB1*1132DR11DR11 
DRB1*1133DR11DR11 
DRB1*1134DR11DR11 
DRB1*1135DR11DR11 
DRB1*1136DR11DR11 
DRB1*1137DR11DR11(5)DR11 
DRB1*1138DR11DR11 
DRB1*1139DR11DR11 
DRB1*1140DR11DR11 
DRB1*1141DR11DR11 
DRB1*1142DR11DR11 
DRB1*1143DR11DR11 
DRB1*1144DR11DR11 
DRB1*1145DR11DR11 
DRB1*1146DR11DR11 
DRB1*1147DR11DR11 
DRB1*1148DR11DR11 
DRB1*1149DR11DR11 
DRB1*1150DR11DR11 
DRB1*1151DR11DR11 
DRB1*1152DR11DR11(5)DR14 
DRB1*1153DR11DR11 
DRB1*1154DR11DR11 
DRB1*1155DR11DR11 
DRB1*1156DR11DR11 
DRB1*1157DR11DR11 
DRB1*1158DR11DR11 
DRB1*1159DR11DR11 
DRB1*1160DR11DR11 
DRB1*1161DR11DR11 
DRB1*1162DR11DR11 
DRB1*1201DR12DR12(5)DR12 [85–100], DR13 [5–12]9DR12 [83], DR5 [4], DR8 [2], DR11 [2]893Training – DR12 
DRB1*1202DR12DR12(5)DR12 [91–100]17DR12 [89]162Training – DR12 
DRB1*1203DR12DR12(5)DR12 [100]b4DR12 
DRB1*1204DR12DR12DR12x11
DRB1*1205DR12DR12(5)DR12 
DRB1*1206DR12DR12(5)DR12 [100]b3DR12 
DRB1*1207DR12DR12 
DRB1*1208DR12DR12 
DRB1*1209DR12DR12 
DRB1*1210DR12DR12 
DRB1*1211DR12DR12 
DRB1*1212DR12DR12 
DRB1*1213DR12DR12 
DRB1*1214DR12DR12 
DRB1*1215DR12DR12 
DRB1*1301DR13DR13(6)DR13 [90–100], DR6 [0–7]a17DR13 [81], DR6 [14], DR14 [1]3788Training – DR6 DR13 
DRB1*1302DR13DR13(6)DR13 [81–97], DR6 [7–11]a17DR13 [74], DR6 [17], DR14 [2]3081Training – DR6 DR13 
DRB1*1303DR13DR13(6)DR13 [50–93], DR6 [4–21], DR‘1303’ [0–11], DR14 [0–17], DR3 [0–8]11DR13 [69], DR6 [10], DR12 [3], DR11 [3], DR5 [2], DR14 [2]948Training – DR6 DR13 
DRB1*1304DR13DR13(6)DR13 [87]127DR13 
DRB1*1305DR13DR13(6)DR13 [48–62], DR11 [11–34], DR6 [5–20], DR14 [3–8]3DR13 [54], DR6 [12], DR11 [7], DR12 [6], DR5 [4]305DR6 
DRB1*1306DR13DR13(6)DR13 [95]1DR13 [88], DR6 [12]b8DR13 
DRB1*1307DR13DR13(6)DR13 [100]b1Not assignedcNN: DR11, DR6
DRB1*1308DR13DR13(6)DR13 [84], DR6 [5]1DR13 [100]b5DR13 
DRB1*1309DR13DR13 [100]b1DR6fNN: DR13
DRB1*1310DR13DR13(6)DR13 [80–95], DR6 [7–15], DR14 [0–10]a5DR13 [100]b4DR13 
DRB1*1311DR13DR13(6)DR13 [72–90], DR11 [0–28], DR14 [0–10], DR6 [0–6]a2DR6 [50], blank [50]b2DR11 
DRB1*1312DR13DR13(6)dDR13 [50], DR6 [13], DR12 [13], DR11 [13]b8DR13DR13x12
DRB1*1313DR13DR13(6)dDR13 [83], DR6 [13]1DR6DR52 negative; NN: DR13, DR8
DRB1*1314DR13DR13(6)DR13 [69–77], DR11 [0–15], DR14 [0–9], DR6 [0–5]a3DR11 [50], blank [50]b2DR11 
DRB1*1315DR13DR13 
DRB1*1316DR13DR13(6)DR13 
DRB1*1317DR13DR13(6)DR13 [53], DR8 [41], DR11 [6]a1Not assignedcDR13x8; NN: DR8
DRB1*1318DR13DR13(6)Not assignedcNN: DR6, DR11
DRB1*1319DR13DR13(6)dDR13NN: DR14
DRB1*1320DR13DR13(6)DR13 [87–95], DR6 [0–5]a2DR13 
DRB1*1321DR13/DR11DR13 [50], blank [50]b2DR11 
DRB1*1322DR13DR13(6)dDR13 [100]b1DR13fNN: DR6
DRB1*1323DR13DR13NN: DR6
DRB1*1324DR11DR11 
DRB1*1325DR11DR11 
DRB1*1326DR14DR14DR blank DR52 positive
DRB1*1327DR13DR13(6)DR13 
DRB1*1328DR13DR13 
DRB1*1329DR13DR13(6)dDR13 [72–90], DR6 [0–9]a2DR13 
DRB1*1330UndefinedNot assignedcNN: DR13, DR6, DR11
DRB1*1331DR13DR13 [80], DR14 [10]a1DR13 
DRB1*1332DR13DR13 
DRB1*1333DR13DR13 
DRB1*1334DR13DR13 
DRB1*1335DR13DR13 
DRB1*1336DR13DR13(6)DR13 [91–100], DR6 [0–5], DR14 [0–4]a3DR6 [100]b1DR13 
DRB1*1337DR13DR13 
DRB1*1338DR13DR13 
DRB1*1339DR13DR13 
DRB1*1340DR13DR13 
DRB1*1341DR13DR13 
DRB1*1342DR6DR13(6)DR6 
DRB1*1343DR13DR13 
DRB1*1344UndefinedNot assignedcNN: DR11
DRB1*1345DR13DR13 
DRB1*1346DR11DR11 
DRB1*1347UndefinedNot assignedcNN: DR8
DRB1*1348DR13DR13 
DRB1*1349DR6DR6 
DRB1*1350DR11DR11 
DRB1*1351DR13DR13 
DRB1*1352DR13DR13(6)DR13 
DRB1*1353DR13DR13 
DRB1*1354DR14DR14(6)Not assignedcNN: DR11
DRB1*1355UndefinedNot assignedcNN: DR8, DR6
DRB1*1356DR6DR6NN: DR13
DRB1*1357DR13DR13(6)DR13 
DRB1*1358DR13DR13 
DRB1*1359DR13DR13 
DRB1*1360DR6DR6DRB5*02 associated (60)
DRB1*1361DR13DR13 
DRB1*1362DR11DR11 
DRB1*1363DR13DR13 
DRB1*1364DR13DR13 
DRB1*1365DR13DR13 
DRB1*1366DR13DR13(6)DR13 
DRB1*1367DR13DR13 
DRB1*1368DR13DR13 
DRB1*1369DR13DR13 
DRB1*1370DR13DR13 
DRB1*1371DR13DR13 
DRB1*1372DR13DR13 
DRB1*1373DR13DR13 
DRB1*1374DR13DR13 
DRB1*1375UndefinedNot assignedcNN: DR11, DR13, DR6
DRB1*1376DR13DR13 
DRB1*1378DR13DR13 
DRB1*1379DR13DR13 
DRB1*1401DR14DR14(6)DR14 [91–100], DR6 [0–7]a18DR14 [74], DR6 [14], DR13 [3]1942Training – DR6 DR14 
DRB1*1402DR14DR14(6)DR14 [50–83], DR6 [12–17], DR17 [8–15], DR13 [0–19]9DR14 [61], DR6 [13], DR13 [9]204Training – DR6 DR14 
DRB1*1403DR1403/DR14DR1403DR14 [72], DR6 [12]37DR14 
DRB1*1404DR1404/DR14DR1404DR14 [84–89], DR1404 [5–8], DR6 [3–7], DR8 [0–10]8DR14 [79], DR6 [8], DR1404 [3]80DR14 
DRB1*1405DR14DR14(6)DR14 [74–85], DR6 [11–15], DR3 [0–13]2DR14 [86], DR6 [10]58DR14 
DRB1*1406DR14DR14(6)DR13 [28], DR14 [26], DR6 [19], DR3 [11]1DR14 [37], DR13 [22], DR6 [15]117Training – DR6 DR14 
DRB1*1407DR14DR14(6)DR14 [87–96], DR6 [0–4]a2DR14 [94]b16DR14 
DRB1*1408DR14DR14(6)dDR14 [94]1DR14 [50], DR6 [25]b4DR14 
DRB1*1409DR14DR14 
DRB1*1410DR14DR14(6)DR14 [76–83], DR6 [4–10]2DR14 [100]b4Not assignedcNN: DR4, DR14, DR6
DRB1*1411DR14DR14(6)DR14 [59], DR6 [12], DR11 [12], DR‘14x11’ [9]1DR14 [100]b1Not assignedcDR14x11; NN: DR14
DRB1*1412DR14DR14(6)DR14NN: DR6
DRB1*1413DR14DR14(6)DR14 [59–86], DR6 [4–17], DR13 [0–10]3DR6 [100]b1DR14 
DRB1*1414DR14DR14(6)DR14 [88–89], DR13 [0–5]2DR14 
DRB1*1415DR8DR8DR8 [50], DR14 [26], DR13 [8]1DR8 [100]b1DR8DR8 + DR52
DRB1*1416DR6DR6DR14 [100]b1DR13DR14x13
DRB1*1417DR6DR6DR13 [100]b1DR6DR14x13; DR13 weak, DR14 negative
DRB1*1418DR14DR6DR14 [100]b1DR14 
DRB1*1419DR14DR14(6)DR14 
DRB1*1420DR14DR14(6)Blank [100]b1DR14 
DRB1*1421DR14DR14(6)DR14 [57–84], DR13 [8–29], DR6 [4–14], DR17 [0–6]a3DR6 [100]b1DR6Also typed as DR13
DRB1*1422DR14DR14(6)dDR14 
DRB1*1423DR14DR14 [100]b1DR14 
DRB1*1424DR14DR14 
DRB1*1425DR6DR6 
DRB1*1426DR14DR14(6)DR14 
DRB1*1427DR14DR14(6)DR6NN: DR14
DRB1*1428DR14DR14 
DRB1*1429DR14DR14(6)DR14 
DRB1*1430DR6DR6 
DRB1*1431DR14DR14 
DRB1*1432DR14DR14 
DRB1*1433DR6DR6NN: DR14
DRB1*1434DR14DR14 
DRB1*1435DR14DR14 
DRB1*1436DR14DR14 
DRB1*1437DR14DR14 
DRB1*1438DR14DR14 
DRB1*1439DR14DR14 
DRB1*1440DR14DR14 
DRB1*1441DR14DR14 
DRB1*1442UndefinedNot assignedcNN: DR11
DRB1*1443DR14DR14 
DRB1*1444DR14DR14 
DRB1*1445DR14DR14 
DRB1*1446DR14DR14 
DRB1*1447DR14DR14 
DRB1*1448DR14DR14 
DRB1*1449DR14DR14(6)DR14 
DRB1*1450DR14DR14(6)Not assignedcNN: DR14, DR6
DRB1*1451DR14DR14 
DRB1*1452DR14DR14 
DRB1*1453DR13/14DR13(6)DR11 
DRB1*1454DR14DR14 [100]a3DR14 [89]b9DR14 
DRB1*1455DR14DR14 
DRB1*1456DR14DR14 
DRB1*1457DR4/DR6DR4NN: DR6
DRB1*1458DR14DR14 
DRB1*1459DR14DR14 
DRB1*1460DR14DR14(6)DR14 
DRB1*1461DR14DR14 
DRB1*1462DR14DR14 
DRB1*1463DR6DR6fNN: DR14
DRB1*1464DR14DR14 
DRB1*1465DR6DR6fNN: DR14
DRB1*1466DR14DR14 
DRB1*1467DR6DR6fNN: DR14
DRB1*1468DR14DR14 
DRB1*1501DR15DR15(2)DR15 [75–90], DR2 [0–19], DR16 [0–13]a31DR15 [76], DR2 [23]6428Training – DR2 DR15 
DRB1*1502DR15DR15(2)DR15 [82–100], DR2 [0–14]a17DR15 [77], DR2 [16]676Training – DR2 DR15 
DRB1*1503DR15DR15(2)DR15 [81–94], DR2 [3–13], DR16 [0–6]a8DR15 [81], DR2 [13]286Training – DR2 DR15 
DRB1*1504DR15DR15(2)dDR15 [76–91], DR2 [0–18], DR16 [0–6]a4DR15 [100]b1DR15 
DRB1*1505DR15DR15(2)DR15 [100]b1DR15 
DRB1*1506DR15DR15(2)DR15 [100]b2DR15 
DRB1*1507DR15DR15(2)dDR15 [82–91], DR2 [5–9], DR16 [0–9]a2DR15 
DRB1*1508DR15DR2DR15 
DRB1*1509DR15DR15 
DRB1*1510DR2DR2NN: DR15
DRB1*1511DR15DR15 
DRB1*1512DR15DR15 
DRB1*1513DR2DR2NN: DR15, DR16
DRB1*1514DR15DR15 [100]b1DR15 
DRB1*1515DR15DR15 
DRB1*1516DR15DR15 
DRB1*1517NNot expressedNullNT 
DRB1*1518DR15DR15 
DRB1*1519DR15DR15 
DRB1*1520DR15DR15 
DRB1*1521DR2DR2fNN: DR15, DR16
DRB1*1522DR15DR15 
DRB1*1601DR16DR16(2)DR16 [31], DR15 [38], DR2 [31]1DR16 [41], DR2 [29], DR15 [19]703Training – DR2 DR16 
DRB1*1602DR16DR16(2)DR16 [56–82], DR2 [12–28], DR15 [6–22]a13DR16 [47], DR2 [30], DR15 [16]239Training – DR2 DR16 
DRB1*1603DR16DR2DR16 
DRB1*1604DR16DR16(2)DR16 [53–64], DR15 [16–27], DR2 [9–31]a2DR16 [100]b1DR16 
DRB1*1605DR16DR16(2)dDR16 [100]b1DR16 
DRB1*1607DR16DR16 
DRB1*1608DR16