Full-length sequence of a novel HLA-B*15:220 allele identified in an individual from Guadeloupe

Authors


Marcel G. J. Tilanus
Transplantation Immunology
Tissue Typing Laboratory
Maastricht University Medical Centre
P.O. Box 5800
6202 AZ Maastricht
The Netherlands
Tel: 31 43 3874680
Fax: 31 43 3874678
e-mail: m.tilanus@mumc.nl

Abstract

The new HLA-B*15:220 allele shows a single-nucleotide substitution in exon 1 at position 47 (C>T) when compared to its closest allele HLA-B*15:03:01, resulting in an amino acid substitution from Ala to Val in the signal peptide at codon −9.

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