Full-length sequence of a novel HLA-B*15:220 allele identified in an individual from Guadeloupe


Marcel G. J. Tilanus
Transplantation Immunology
Tissue Typing Laboratory
Maastricht University Medical Centre
P.O. Box 5800
6202 AZ Maastricht
The Netherlands
Tel: 31 43 3874680
Fax: 31 43 3874678
e-mail: m.tilanus@mumc.nl


The new HLA-B*15:220 allele shows a single-nucleotide substitution in exon 1 at position 47 (C>T) when compared to its closest allele HLA-B*15:03:01, resulting in an amino acid substitution from Ala to Val in the signal peptide at codon −9.