Association of passive exposure of pregnant women to environmental tobacco smoke with asthma symptoms in children

  1. Paraskevi Xepapadaki1,
  2. Yannis Manios2,
  3. Theodoros Liarigkovinos2,
  4. Evangelia Grammatikaki2,
  5. Nikolaos Douladiris1,
  6. Christine Kortsalioudaki2,
  7. Nikolaos G. Papadopoulos1

Article first published online: 22 JUL 2009

DOI: 10.1111/j.1399-3038.2008.00820.x

Issue

Pediatric Allergy and Immunology

Pediatric Allergy and Immunology

Volume 20, Issue 5, pages 423–429, August 2009

Additional Information

How to Cite

Xepapadaki, P., Manios, Y., Liarigkovinos, T., Grammatikaki, E., Douladiris, N., Kortsalioudaki, C. and Papadopoulos, N. G. (2009), Association of passive exposure of pregnant women to environmental tobacco smoke with asthma symptoms in children. Pediatric Allergy and Immunology, 20: 423–429. doi: 10.1111/j.1399-3038.2008.00820.x

Author Information

  1. 1

    Allergy Department, 2nd Pediatric Clinic, University of Athens, Goudi, Greece

  2. 2

    Department of Nutrition & Dietetics, Harokopio University, Athens, Greece

*Paraskevi Xepapadaki, Allergy Department, 2nd Pediatric Clinic, University of Athens, 13 Levadias str., Goudi 11527, Greece Tel.: +30 (210)7714626 Fax: +30 (210)7776964 E-mail: panvik@hol.gr

Publication History

  1. Issue published online: 22 JUL 2009
  2. Article first published online: 22 JUL 2009
  3. Accepted 15 September 2008

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Keywords:

  • allergy;
  • asthma;
  • passive smoking;
  • pregnancy;
  • tobacco smoke

Environmental tobacco smoke (ETS) is a significant risk factor for the presence and increased severity of asthma- and allergy-related symptoms in children. Smoking during pregnancy has detrimental effects on asthma-associated outcomes in childhood. Whether passive exposure of pregnant women to ETS may also lead to asthma in their offspring, is not known. The aim of this study was to investigate the association of passive exposure of pregnant women to ETS and asthma- and/or allergy-related symptoms in Preschool children. Cross-sectional data were collected with questionnaires from 2374 Preschool children, recruited from public and private nurseries and day-care centers. Parental smoking was significantly associated with wheezing symptoms in their children. Mother’s active smoking during pregnancy significantly increased the risk for occurrence of asthma symptoms and/or medically diagnosed asthma in Preschool children in a dose-dependent manner. Passive exposure to ETS, mainly during the third trimester of pregnancy, was significantly associated with asthma- and allergy-related symptoms after adjusting for several confounders in a multivariate analysis (current wheeze: OR = 1.42, 95% CI = 1.06–1.91, pruritic rash ever: OR= 1.45, 95% CI = 1.01–2.08). Passive exposure of pregnant women to ETS during the third trimester is positively associated with asthma- and allergy-related symptoms in their Preschool age children. Public health policies should be oriented not only towards smoking cessation, but also reinforce elimination of ETS exposure of pregnant women.

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