Current immunosuppressive agents in pediatric renal transplantation: Efficacy, side-effects and utilization


Jodi M. Smith, Division of Nephrology, Children's Hospital and Regional Medical Center, 4800 Sand Point Way NE, M1–5, Seattle 98105, WA, USA. Tel.: 206-987-2524 Fax: 206-987-2636


Abstract:  Advances in immunosuppressive therapy over the past decade have led to dramatic improvements in graft survival. The immunosuppression that is used is center-dependent and is constantly evolving with the development of new medications. The goal remains to find the best combination that will optimize graft survival, while minimizing the adverse effects.