Effect of kidney transplantation on heart conduction disturbances in children treated with chronic hemodialysis – A pilot study
Article first published online: 23 NOV 2011
© 2011 John Wiley & Sons A/S
Volume 15, Issue 8, pages 835–843, December 2011
How to Cite
Polak-Jonkisz, D., Laszki-Szcząchor, K., Sobieszczańska, M., Makulska, I., Pilecki, W., Rusiecki, L. and Zwolińska, D. (2011), Effect of kidney transplantation on heart conduction disturbances in children treated with chronic hemodialysis – A pilot study. Pediatric Transplantation, 15: 835–843. doi: 10.1111/j.1399-3046.2011.01588.x
- Issue published online: 23 NOV 2011
- Article first published online: 23 NOV 2011
- Accepted for publication 15 August 2011
- kidney transplantation;
- left bundle branch block;
- isochrone maps
Polak-Jonkisz D, Laszki-Szcząchor K, Sobieszczańska M, Makulska I, Pilecki W, Rusiecki L, Zwolińska D. Effect of kidney transplantation on heart conduction disturbances in children treated with chronic hemodialysis – A pilot study. Pediatr Transplantation 2011: 15: 835–843. © 2011 John Wiley & Sons A/S.
Abstract: Aim of the study was to assess the effect of KT on heart conduction in HD children. Non-invasive electrocardiographic method of BSPM was used. Isochrone maps, presenting a VAT distribution, were taken from eight HD patients and 26 normal subjects. Patients were divided into two groups: I – three children were HD <12 months prior to KT; II – five children were HD >12 months prior to KT. After KT, the groups were marked as IP and IIP. Serum iPTH and phosphate levels were significantly higher in both HD groups than in controls, with a considerable normalization after transplantation. HD patients demonstrated neither conduction abnormalities on ECG nor left ventricular hypertrophy. Group-mean VAT maps revealed: I and II – similar patterns of complete LBBB; IP – partial normalization to a pattern of anterior fascicle block; IIP – preserved pattern of LBBB. Intraventricular conduction disturbances found in HD children using BSPM were alleviated by KT. Short HD therapy increases a chance of conduction disturbances regression after KT, contrary to the longer HD treatment. BSPM is more sensitive than standard ECG in detecting heart conduction impairments in the HD patients.