Cardiac magnetic resonance imaging in children with chronic kidney disease and renal transplantation
Article first published online: 12 MAR 2012
© 2012 John Wiley & Sons A/S
Volume 16, Issue 4, pages 350–356, June 2012
How to Cite
Schaefer, B., Rusai, K., Toth, A., Pasti, K., Ujszaszi, A., Kreko, M., Horvath, E., Sallay, P., Reusz, G. S., Merkely, B., Tulassay, T. and Szabo, A. J. (2012), Cardiac magnetic resonance imaging in children with chronic kidney disease and renal transplantation. Pediatric Transplantation, 16: 350–356. doi: 10.1111/j.1399-3046.2012.01672.x
- Issue published online: 14 MAY 2012
- Article first published online: 12 MAR 2012
- Accepted for publication 23 January 2012
Vol. 17, Issue 1, 92, Article first published online: 22 JAN 2013
- chronic renal failure;
- pediatric kidney transplantation;
- cardiac function
Schaefer B, Rusai K, Toth A, Pasti K, Ujszaszi A, Kreko M, Horvath E, Sallay P, Reusz GS, Merkely B, Tulassay T, Szabo AJ. Cardiac magnetic resonance imaging in children with chronic kidney disease and renal transplantation.
Abstract: CV disease is the major cause of death in patients with CKD. Recently, CMR imaging emerges as a complementary method providing advantages in cardiac assessment; however, data on CMR in pediatric CKD are scarce. We performed CMR in 15 children: two with CKD, six on peritoneal dialysis, seven on hemodialysis, and in 18 children 5.1 (0.4–15.4) yr after kidney Tx. Eight children underwent CMR six months before and after Tx. Results are presented as mean z score ± SD. LV EF was higher and in the normal range in Tx patients compared with CKD (−0.3 ± 1 vs. −2.1 ± 1.6, respectively, p < 0.05), whereas RV EF was similar (−0.9 ± 1.4 vs. −0.9 ± 1.8, p = n.s.). End-diastolic and end-systolic LV volume index (0 ± 1.7 vs. 2.1 ± 3.1; 0.2 ± 1.2 vs. 3.1 ± 3.7, both p < 0.05) and LV mass index (1.4 ± 1.5 vs. 3.4 ± 2.9, p < 0.05) were lower in Tx children. All parameters improved in the eight children after Tx. In conclusion, our CMR analysis suggests marked improvement of cardiac function and morphology in children after kidney Tx. CMR might be an appropriate complementary method for measuring detailed cardiac status in children with CKD.