This paper is dedicated to Dr Marilyn Griffith, who passed away on February 19th, 2005, to recognize her outstanding contribution to research on cold stress in plants.
Histidine kinase Hik33 is an important participant in cold-signal transduction in cyanobacteria
Article first published online: 16 JAN 2006
Volume 126, Issue 1, pages 17–27, January 2006
How to Cite
Murata, N. and Los, D. A. (2006), Histidine kinase Hik33 is an important participant in cold-signal transduction in cyanobacteria. Physiologia Plantarum, 126: 17–27. doi: 10.1111/j.1399-3054.2006.00608.x
Edited by C. Guy
- Issue published online: 16 JAN 2006
- Article first published online: 16 JAN 2006
- Received 5 September 2005; revised 17 September 2005
Acclimation of living organisms to cold stress begins with the perception and transduction of the cold signal. However, traditional methods failed to identify the sensors and transducers of cold stress. Therefore, we combined systematic mutagenesis of potential sensors and transducers with DNA microarray analysis in an attempt to identify these components in the cyanobacterium Synechocystis sp. PCC 6803. We identified histidine kinase Hik33 as a potential cold sensor and found that Hik33 participates in the regulation of the expression of more than 60% of the cold-inducible genes. Further study revealed that Hik33 is also involved in the perception of hyperosmotic stress and salt stress and transduction of the signals. Complexity of responses to cold and other environmental stresses is discussed.