Lethal human herpesvirus-6 encephalitis after cord blood transplant

  1. F. Forest1,
  2. S. Duband1,
  3. S. Pillet2,
  4. M.-L. Stachowicz1,
  5. J. Cornillon3,
  6. J.-M. Dumollard1,
  7. M. Peoc'h1

Article first published online: 31 AUG 2011

DOI: 10.1111/j.1399-3062.2011.00642.x

Issue

Transplant Infectious Disease

Transplant Infectious Disease

Volume 13, Issue 6, pages 646–649, December 2011

Additional Information

How to Cite

Forest, F., Duband, S., Pillet, S., Stachowicz, M.-L., Cornillon, J., Dumollard, J.-M. and Peoc'h, M. (2011), Lethal human herpesvirus-6 encephalitis after cord blood transplant. Transplant Infectious Disease, 13: 646–649. doi: 10.1111/j.1399-3062.2011.00642.x

Author Information

  1. 1

    Department of Pathology

  2. 2

    Laboratory of Bacteriology-Virology, University Hospital Center of Saint-Etienne, Saint-Etienne, France

  3. 3

    Department of Hematology, Loire Cancerology Institute, Saint-Etienne, France

* M. Peoc'h, Department of Pathology, University Hospital Center of Saint-Etienne, Hopital Nord 420055 Saint-Etienne, Cedex 02, France Tel: 33 (0) 4 77 12 77 34 Fax: 33 (0) 04 77 12 09 16 E-mail: michel.peoch@chu-st-etienne.fr

Publication History

  1. Issue published online: 20 DEC 2011
  2. Article first published online: 31 AUG 2011
  3. Received 4 October 2010, revised 26 December 2010, accepted for publication 5 February 2011

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Keywords:

  • HHV-6;
  • encephalitis;
  • acute leukemia;
  • cord blood transplant

F. Forest, S. Duband, S. Pillet, M.-L. Stachowicz, J. Cornillon, J.-M. Dumollard, M. Peoc'h. Lethal human herpesvirus-6 encephalitis after cord blood transplant. Transpl Infect Dis 2011: 13: 646–649. All rights reserved

Abstract: Clinical, biological, pathological, and imaging findings were all suggestive of lethal human herpesvirus-6-associated encephalitis in a 61-year-old man who had undergone a cord blood transplant. The neuropathological findings of this unusual autopsy case and the pathogenesis of this infection in immunocompromised patients are discussed.

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