These authors contributed equally to this work and both are considered co-first authors
Chronic hepatitis E in hematopoietic stem cell transplant patients in a low-endemic country?
Version of Record online: 28 DEC 2011
© 2011 John Wiley & Sons A/S
Transplant Infectious Disease
Volume 14, Issue 1, pages 103–106, February 2012
How to Cite
- Issue online: 13 FEB 2012
- Version of Record online: 28 DEC 2011
- Manuscript Accepted: 6 NOV 2011
- Manuscript Revised: 28 OCT 2011
- Manuscript Received: 6 AUG 2011
- hepatitis E virus;
- stem cell transplantation;
- bone marrow transplantation
Cases of chronic hepatitis E have been described in patients after kidney and liver transplantation. In addition, hepatitis E virus (HEV) reactivation was reported after hematopoietic stem cell transplantation (HSCT). We here evaluated if HEV infection might explain elevated liver enzymes in a well selected cohort of allogeneic HSCT patients with biochemical evidence of hepatitis (n = 52). Of note, none of the subjects tested positive for HEV RNA, including 2 HSCT patients who had been infected with HEV already before transplantation. Thus, both chronic courses of HEV infections and HEV reactivations seem to be rather rare events in HSCT patients in a non-endemic country.