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Keywords:

  • bronchiectasis;
  • bronchiolitis obliterans syndrome;
  • inhaled ribivirin;
  • lung transplantation;
  • respiratory syncytial virus

Abstract

Bronchiolitis obliterans syndrome (BOS) can have either an acute or chronic onset with an abrupt or insidious course. The diagnosis is typically achieved by physiological criteria with development of a sustained decline in expiratory flow rates for at least 3 weeks. We review the rapid development of acute BOS and bronchiectasis after respiratory syncytial virus infection in a lung transplant recipient, who had been doing well with normal pulmonary function for 3 years after lung transplantation.