Dr George Knafl was at Yale School of Nursing when this study was conducted.
The transition to young adulthood in youth with type 1 diabetes on intensive treatment
Version of Record online: 19 JUL 2007
2007 Blackwell Munksgaard
Volume 8, Issue 4, pages 228–234, August 2007
How to Cite
Insabella, G., Grey, M., Knafl, G. and Tamborlane, W. (2007), The transition to young adulthood in youth with type 1 diabetes on intensive treatment. Pediatric Diabetes, 8: 228–234. doi: 10.1111/j.1399-5448.2007.00266.x
This study was supported by grants from NINR (1&2RO1NR04009), the Culpeper Foundation to Margaret Grey, and the General Clinical Research Centers Program (Grant MO1-RR00125), National Center for Research Resources.
- Issue online: 19 JUL 2007
- Version of Record online: 19 JUL 2007
- Submitted 5 July 2006. Accepted for publication 21 May 2007
- metabolic control;
- quality of life;
- type 1 diabetes;
- young adulthood
Objective: We sought to examine prospectively patterns of clinical and psychosocial outcomes during the transition from adolescence to young adulthood in a cohort initiating intensive therapy after the Diabetes Control and Complications Trial.
Research design and methods: We conducted a prospective, descriptive analysis of data from a randomized intervention study with 117 adolescents (45 males and 72 females, mean age at entry = 14.4 ± 2.0 yr, mean diabetes duration at entry = 5.7 ± 3.7 yr) recruited from a large pediatric diabetes clinic. Data were collected for each subject over periods of up to 5 yr at 6-month intervals using measures of depressive symptoms, quality of life, and metabolic control, with chart review for prevalence of diabetes complications.
Results: Metabolic control worsens during adolescence but returns to early adolescent levels in young adulthood. The negative impact of diabetes on quality of life, disease-related worries, and life satisfaction did not change significantly with age. These results did not vary with treatment group or gender. Participants who showed high levels of depressive symptoms as adolescents were somewhat more likely to be depressed when older. Despite relatively long duration of diabetes, relatively few complications were observed in young adulthood.
Conclusions: These data suggest that youth who begin intensive treatment as adolescents generally have good metabolic and psychosocial outcomes as young adults. However, those who have high levels of depressive symptoms in adolescence tend to continue to have such symptoms in early adulthood.