Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls
Version of Record online: 22 NOV 2012
© 2012 John Wiley & Sons A/S
Volume 13, Issue 8, pages 587–596, December 2012
How to Cite
Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls., , , .
- Issue online: 22 NOV 2012
- Version of Record online: 22 NOV 2012
- Manuscript Accepted: 15 MAY 2012
- Manuscript Revised: 13 MAY 2012
- Manuscript Received: 23 NOV 2011
- Swedish Child Diabetes Foundation
- Swedish Research Council. Grant Number: NO 7509
- Local Diabetes Association
- University Hospital Grants
- physical exercise;
- type 1 diabetes
Physical activity is a critical component in the care of diabetes. Although it offers health benefits it presents challenges.
To investigate differences between adolescent boys and girls with type 1 diabetes and healthy controls in terms of maximal work capacity (VO2 max) and hormonal response to physical exercise of different intensities.
Twelve individuals (six boys and six girls; age 14–19 yr, pubertal stage 4–5) with type 1 diabetes (duration, 6.3 ± 4.4 yr; hemoglobin A1c, 63 ± 10 mmol/mol) were compared with 12 healthy controls matched for age, sex, pubertal stage, body mass index standard deviation score, and amount of regular physical activity.
During consecutive days, three different workloads; maximal, endurance, and interval, were performed on an Ergometer cycle. During the tests, levels of lactate, glucose, insulin, and regulatory hormones [glucagon, cortisol, growth hormone (GH), adrenaline, and noradrenaline] were measured in blood. Subcutaneous glucose was measured continuously.
VO2 max did not differ between the groups, diabetes 49.8 ± 9.9 vs. control 50.7 ± 12.0 mL/min/kg. Hormonal responses did not differ between the groups except for mean peak GH level during the interval test, diabetes 63.2 ± 27.0 vs. control 33.8 ± 20.9 mU/L, p < 0.05.
Physical capacity and hormonal regulation of blood glucose in connection with physical exercise of different intensities did not differ between adolescents with diabetes and healthy controls. Thus, adolescents with type 1 diabetes can participate in physical activity on the same terms as healthy peers.